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Notes in
g. Embryology: Neurulation
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Published
07/28/2024
The {{c1::notochord}} initiates the process of neural plate folding via secretion of {{c2::Shh}} which causes differential expression of {{c…
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07/28/2024
The green cells seen on the border of the neural plate during neural tube folding will become what structure after completion of the neural tube?
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How are the lower sacral and coccygeal regions of the neural tube formed?
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Failure for the anterior neuropore to close results in {{c1::anencephaly}}
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Failure of the posterior neuropore to close results in {{c1::spina bifida}}
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{{c1::spina bifida occulta}} is a defect of the transverse process which form vertebral arches in closing that is covered by skin and does not involve…
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{{c1::Spina bifida aperta}} is a defect where the meninges or meninges and neural tissue protrude through the vertebral arches
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The form of spina bifida aperta that occurs when only the meninges protrude through the vertebral arches is called a {{c1::meningoecele}}
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The form of spina bifida aperta that occurs when both the meninges and neural tissue protrude through the vertebral arches is called a {{c1::myel…
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The junction between primary and secondary neurulation is common site for {{c1::spina bifida}} to be observed
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The vertebral column lengthens {{c1::faster}} than the spinal chord
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A {{c1::tethered cord}} can occur when a piece of the spinal chord is stuck to the spine, which can produce {{c2::hydrocephalus}} which occu…
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{{c3::Arnold-Chiari Malformations}} are caused by a {{c1::tethered cord}} causing herniation of the cerebellum and medulla and obstruction of the…
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Neurons migrate from the neural tube by traveling {{c1::radially}} along glial fibers and in an {{c2::inside-out}} fashion starting in the e…
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{{c1::Primary microencephaly}} is caused by the failure of {{c2::cell migration}} in the brain, resulting in a {{c1::small}} brain and head circu…
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Dorsal-ventral patterning of the CNS is established by secreted signaling molecules particularly {{c1::Shh}} from the {{c2::notochord}}
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Shh concentration are observed to be higher near the {{c1::ventral}} side of the embryo
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Bmp Wnt tend to be higher near the {{c1::dorsal}} side of the embryo
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The {{c1::neural crest}} is a transient population of stem cells and restricted progenitors that migrate extensively and give rise to many divers…
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The {{c1::cranial}} neural crest gives rise to bones, cartilage, nerves and connective tissue of the head
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Cleft lips/palates are caused by defects in the {{c1::cranial neural crest}}
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The {{c1::cardiac}} neural crest gives rise to the smooth muscle of the arteries of the aortic arch and the outflow tract
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07/28/2024
Aganglionic megacolon is caused by failure in the development of the {{c1::vagal}} neural crests
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The {{c1::trunk}} neural crest gives rise to the sympathatic and parasympathetic nervous systems, melanocytes, and chromaffin cells
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{{c1::Neuroblastomas}} are the most common extra-cranial solid cancer in children and the most common tumor in infants, they arise within the {{c…
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07/28/2024
{{c1::Neurofibromatosis}} is caused by a mutation in the NF-1 gene which causes the over proliferation of {{c2::neural crest cells}} which drives…
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Neuroblastomas, neurofibromatosis, and Waardenburg syndrome are examples of {{c1::neurocristopathies}} which are neural crest defects
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CNS is sensitive to developing teratogens as a result of toxic exposure, death, or regulation {{c1::throughout}} development whereas other organ syste…
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The three steps in the formation of the primitive nervous system include {{c1::induction, neurulation, and patterning}}
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Describe formation of neural plate
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07/28/2024
Defects of neural tube closure defects include?
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07/28/2024
Neural crest cells form {{c1::many different}} cell types in both the {{c1::mesoderm and ectoderm}}
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