Notes in Female Genitalia

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Published	08/28/2024	The vulva is the external female genitalia and includes the hair-bearing skin (_________) and mucosa (_______). Disorders of the vulva most freque…
Published	08/28/2024	What are some of the most common causes of vulvitis? How does it present/manifest? Complications?
Published	08/28/2024	What is an important complication of vulvitis?
Published	08/28/2024	Define Lichen Sclerosus:
Published	08/28/2024	Histology of Lichen Sclerosus:
Published	08/28/2024	Gross Lichen Sclerosus:
Published	08/28/2024	Which age group is Lichen Sclerosus most common in?
Published	08/28/2024	Pathogenesis of Lichen Sclerosus:
Published	08/28/2024	What do a small minority of individuals with symptomatic Lichen Sclerosus develop?
Published	08/28/2024	Define Lichen Simplex Chronicus:
Published	08/28/2024	What is important to think about when comparing Lichen Sclerosus and Lichen Simplex Chronicus?
Published	08/28/2024	Histologic differences between Lichen Sclerosus and Lichen Simplex Chronicus?
Published	08/28/2024	What are some common causes of Lichen Simplex Chronicus?
Published	08/28/2024	Lichen Simplex Chronicus connection to cancer?
Published	08/28/2024	________ is the name given to any warty lesion of the vulva.
Published	08/28/2024	What are the two distinctive forms of most condylomas?
Published	08/28/2024	Gross appearance of Condyloma (acuminata) on vulva:
Published	08/28/2024	What is condylomata acuminata associated with?
Published	08/28/2024	more than 90% of condylomata acuminata are positive for HPV subtypes ________
Published	08/28/2024	Epidemiology of Carcinoma of the Vulva:
Published	08/28/2024	Carcinoma of the vulva represents about ___% of all female genital tract cancers, occurring mostly in women older than age ___. Approximately ___% of …
Published	08/28/2024	What are the two distinct forms of vulvar squamous cell carcinomas and how do they differ pathogenetically?
Published	08/28/2024	What is the less common form of carcinoma of the vulva (squamous cell)?
Published	08/28/2024	Morphology of Vulvar Carcinoma?
Published	08/28/2024	Clinical features/Progression of Vulvar Carcinoma? Spread? Survival?
Published	08/28/2024	Define Extramammary Paget Disease:
Published	08/28/2024	Extramammary Paget Disease related to cancer? Arise from?
Published	08/28/2024	Clinical manifestation of Paget Disease? Progressuion and prognosis?
Published	08/28/2024	Who gets HPV-related vulvar squamous cell carcinoma?
Published	08/28/2024	Who gets NON HPV vulvar squamous cell carcinoma?
Published	08/28/2024	What is the vulva? What is it lined by?
Published	08/28/2024	What is a Bartholin cyst?
Published	08/28/2024	What female parts are commonly affected by HPV?
Published	08/28/2024	Overview of Pathoma HPV:
Published	08/28/2024	What is the difference between nipple pagets and extramammary paget disease?
Published	08/28/2024	How do we differentiate vulvar extramammary paget disease from vulvar melanoma? HIGH YEILD
Published	08/28/2024	Is vaginal disease common? How is it commonly affected?
Published	08/28/2024	Define Vaginitis: common agents? Presentations seen?
Published	08/28/2024	Define Squamous Cell Carcinoma of the Vagina:
Published	08/28/2024	Define Clear Cell Adenocarcinoma of the Vagina:  Association from the 1970s? Precursor lesion?
Published	08/28/2024	Define Sarcoma botryoides (embryonal rhabdomyosarcoma):
Published	08/28/2024	How is the vaginal canal lining developed? What can go wrong?
Published	08/28/2024	Define Adenosis: Complication? Etiology?
Published	08/28/2024	Which age group is Sarcoma botryoides (embryonal rhabdomyosarcoma) present in? How does it present?
Published	08/28/2024	What is the Rhabdomyoblast?
Published	08/28/2024	Regional lymph node spread seen in vaginal carcinoma?
Published	08/28/2024	Define Cervicitis:
Published	08/28/2024	Most tumors of the cervix are of _____ origin and are caused by oncogenic strains of ___.
Published	08/28/2024	How does the cervix develop?
Published	08/28/2024	HPV, the causative agent of cervical neoplasia, has a tropism for the immature squamous cells of the _________
Published	08/28/2024	What is the precursor lesion of most invasive cervical carcinomas? How does this precursor develop? Risk factors of precursor lesion?
Published	08/28/2024	What are the common risk factors for Cervical Carcinoma?
Published	08/28/2024	How does HPV cause Invasive cervical carcinomas on a molecular level?
Published	08/28/2024	Describe Squamous Intraepithelial Lesion (SIL, Cervical Intraepithelial Lesion) role in invasive cervical carcinoma?  Progression?
Published	08/28/2024	At what age does SIL arise and when does invasive carcinoma of the cervix occur?
Published	08/28/2024	What is the Papanicolaou (Pap) test/smear used for? How is it used?
Published	08/28/2024	Describe the HPV vaccine:
Published	08/28/2024	Morphology/Histology of SIL (CIN) seen in progression to invasive cervical carcinoma? Morphology of Pap Smear?
Published	08/28/2024	Clinical presentation and treatment of different types of SIL (cervical carcinoma precursor)?
Published	08/28/2024	Describe Invasive Carcinoma of the Cervix? Common types of carcinoma? Association? Age? Risk Factors? Morphology? Clinical Features?
Published	08/28/2024	Describe Endocervical Polyp:
Published	08/28/2024	Cervical Neoplasia Summary/HighYield: Discuss HPV and other risk factors? Molecular function of HPV? Screening?
Published	08/28/2024	Pathoma HPV facts:
Published	08/28/2024	Difference between carcinoma and dysplasia?
Published	08/28/2024	Limiations of Pap smear?
Published	08/28/2024	What is the uterus made up of?
Published	08/28/2024	Which cell infilitrate is seen in acute vs chronic endometritis inflammations classically? Clincial Symptoms? Causes?
Published	08/28/2024	Describe Endometritis: Causes? Presentation? Morpholgy?
Published	08/28/2024	Clinical presentation of Endometritis:
Published	08/28/2024	Define Adenomyosis:
Published	08/28/2024	Define Endometriosis: Where does it occur? How common? Presentation?
Published	08/28/2024	What are the 4 hypotheses of Endometriosis pathology?
Published	08/28/2024	Describe the difference of normal endometric tissue vs endometriotic tissue seen in endometriosis?
Published	08/28/2024	Morphology of Endometriosis:
Published	08/28/2024	Clinical Presentation/Features of Endometriosis:
Published	08/28/2024	Describe Abnormal Uterine Bleeding: Causes? Dysfunctional uterine bleeding? Age?
Published	08/28/2024	Describe Dysfunctional Uterine Bleeding:
Published	08/28/2024	The most common proliferative lesions of the uterine corpus are endometrial hyperplasia, endometrial carcinomas, endometrial polyps, and smooth mu…
Published	08/28/2024	Describe Endometrial Hyperplasia: Pathogenesis? Causes? atypia? Complication?
Published	08/28/2024	An excess of estrogen relative to progestin, if sufficiently prolonged or marked, can induce exaggerated endometrial proliferation (hyperplasia), …
Published	08/28/2024	Causes of Endometrial Hyperplasia?
Published	08/28/2024	Describe the two different categories of Endometrial Hyperplasia? Histologically
Published	08/28/2024	In the United States and many other Western countries, __________ is the most frequent cancer occurring in the female genital tract.   …
Published	08/28/2024	Describe Endometrial Carcinoma: Prevelance? Age? Groups? Morphology?
Published	08/28/2024	Pathogenesis of Endometrial Carcinoma: 2 types?
Published	08/28/2024	Morphology of Endometrial Carcinoma: Endometrioid Carcinoma vs Serous Carcinoma?
Published	08/28/2024	Clinical Features of Endometrial Carcinoma:
Published	08/28/2024	Describe Endometrial Polyps:
Published	08/28/2024	Describe Leiomyoma (Fibroids):
Published	08/28/2024	Describe Leiomyosarcoma:
Published	08/28/2024	Describe Asherman Syndrome:
Published	08/28/2024	Describe Anovulatory Cycle:
Published	08/28/2024	Where are common sites of Endometriosis:
Published	08/28/2024	What is a complication of endometriosis (especially in the ovary)? Compication of Endometriosis in Fallopian tube?
Published	08/28/2024	Endometrial Hyperplasia is the Hyperplasia of Endometrial glands ____ to stroma
Published	08/28/2024	In which tumors is Psammoma body formation seen?
Published	08/28/2024	Key distinguishing factor between Leiomyoma and Leiomyosarcoma?
Published	08/28/2024	The most common disorder of the fallopian tubes is inflammation (______), almost invariably occurring as a component of pelvic inflammatory diseas…
Published	08/28/2024	Define Salpingitis:
Published	08/28/2024	Describe Adenocarcinomas of the Fallopian Tube:
Published	08/28/2024	Describe Follicle and Luteal Cysts (Ovary):
Published	08/28/2024	Describe Polycystic Ovarian Syndrome (PCOD):
Published	08/28/2024	Describe the basic principles of the OVARY:
Published	08/28/2024	What diseases are associated with Polycystic Ovarian Syndrome (PCOD)?
Published	08/28/2024	In the United States it is estimated that there will be over 20,000 ovarian cancer cases diagnosed in 2016 leading to over 14,000 deaths, making o…
Published	08/28/2024	Describe Surface Epitehlial Tumors of the Ovary:
Published	08/28/2024	Describe Serous Tumors of the Ovary:
Published	08/28/2024	Describe Mucinous Tumors of the Ovary:
Published	08/28/2024	Describe Endometrioid Tumors of the ovary:
Published	08/28/2024	Describe Brenner Tumors of the ovary:
Published	08/28/2024	Robbins: Many other types of tumors of germ cell and sex cord–stromal origin also arise in the ovary, but only the teratomas of germ cell origin are s…
Published	08/28/2024	Describe the 3 types of Teratomas of the Ovary:
Published	08/28/2024	Clinical features of Ovarian Neoplasms:
Published	08/28/2024	Describe Sex Cord-Stromal tumors of the ovary:
Published	08/28/2024	Describe Germ Cell Tumors of the ovary:
Published	08/28/2024	Ovary is composed of three cell types: ________, __________, _________
Published	08/28/2024	Describe Dysgerminoma of the ovary:
Published	08/28/2024	Describe Endodermal Sinus Tumor of Ovary:
Published	08/28/2024	Describe Choriocarcinoma of the Ovary:
Published	08/28/2024	Describe Embryonal Carcinoma of the Ovary:
Published	08/28/2024	Describe Granulosa-Theca cell tumor of the Ovary:
Published	08/28/2024	Describe Sertoli-Leydig cell tumor of the Ovary:
Published	08/28/2024	Describe Fibroma tumor of the Ovary:
Published	08/28/2024	Describe Metastasis to the Ovary:
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