Notes in Case 1: Tuberculosis

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Published	06/16/2024	{{c2::Rifampin::Antibacterial}} works by binding to bacterial {{c1::DNA-dependent RNA polymerase}}, inhibiting RNA synthesis
Published	06/16/2024	Rifampin use is associated with {{c1::hepato}}toxicity
Published	06/16/2024	If you're treating a patient with tuberculosis, should you wear a simple facemask or N95 respirator?{{c1::N95 respirator}}
Published	06/16/2024	Latent tuberculosis remains in 4 organs:{{c1::posterior apical lungs}}{{c2::subependymal brain}}{{c3::renal cortex}}{{c4::vertebral bodies}}
Published	06/16/2024	If XR abd/pelvis shows beading of ureters and blunting of calyces and you suspect reactivated tuberculosis, you could order {…
Published	06/16/2024	PPD skin test screens for TB {{c1::infection}}, not {{c1::disease}}
Published	06/16/2024	If CXR shows Ranke complex and you suspect reactivated tuberculosis, you could order {{c1::first-morning sputum culture x3}} to co…
Published	06/16/2024	Although the carbol fuchsin stain is classically used to identify acid-fast bacteria, {{c1::auramine-rhodamine}} is now used more frequently beca…
Published	06/16/2024	Patient with latent TB can take TNF inhibitor if and only if they {{c1::start INH + pyridoxine first}}
Published	06/16/2024	Bacterial meningitis progresses {{c1::rapidly::speed}}, while TB/fungal meningitis progresses {{c1::slowly::speed}}
Published	06/16/2024	A(n) {{c2::Ghon focus}} is a(n) {{c1::caseating granuloma::specific}} located near the pleura in the middle or lower lobes of the lung (tuberculosis i…
Published	06/16/2024	Active Mycobacterium tuberculosis infection is treated with RIPE therapy:{{c1::Rifampin::R}}{{c1::Isoniazid::I}}{{c1::Pyrazinamide::P}}{{c1::Ethambuto…
Published	06/16/2024	Isoniazid is administered with {{c1::pyridoxine (vitamin B6)}} in patients at risk for peripheral neuropathy as well as those who are pregnant, breast…
Published	06/16/2024	A(n) {{c2::Ranke}} complex is a Ghon complex that has undergone progressive fibrosis and subsequent {{c1::calcification}}
Published	06/16/2024	Isoniazid (INH) is a prodrug that is activated by {{c1::KatG (a catalase-peroxidase)}}, which is produced by Mycobacterium tuberculosis
Published	06/16/2024	Isoniazid hepatotoxicity results in an asymptomatic rise in {{c1::aminotransferases (AST, ALT)}} on liver function tests
Published	06/16/2024	Which of the RIPE drugs is bacteriostatic?{{c1::Ethambutol}}
Published	06/16/2024	Pyrazinamide is an antibiotic only used to treat {{c1::Mycobacterium tuberculosis}}
Published	06/16/2024	What is the next step in management for a patient being treated with RIPE therapy for TB for the past month that develops mild elevations in AST/ALT? …
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