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Notes in
BIO 1A - Lecture 4 1/31
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Phospholipids are the most abundant lipid in the {{c1::plasma membrane}}.
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Phospholipids are {{c1::amphipathic}}, with hydrophilic and hydrophobic regions.
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What does the fluid mosaic model describe?
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In the phospholipid bilayer, hydrophilic heads face {{c1::water}}.
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{{c1::image-occlusion:rect:left=.0844:top=.1621:width=.2386:height=.2082:oi=1}}{{c2::image-occlusion:rect:left=.0763:top=.4863:width=.2695:height=.249…
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Phospholipids in the plasma membrane move laterally {{c1::frequently}} but flip-flop {{c2::rarely}}.
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What type of hydrocarbon tails make the membrane fluid?
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What type of hydrocarbon tails make the membrane viscous?
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Cholesterol in the cell membrane helps maintain fluidity by preventing {{c1::tight packing}} of phospholipids.
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What kind of movement and membrane condition does this image depict?
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Where are peripheral proteins located?
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Integral proteins penetrate the {{c1::hydrophobic core}} of the membrane.
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What are integral proteins that span the membrane called?
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The hydrophobic regions of integral proteins consist of {{c1::nonpolar amino acids}} coiled into {{c2::alpha helices}}.Back:
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How do transmembrane proteins differ from other integral proteins?
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The six major functions of membrane proteins are transport, enzymatic activity, {{c1::signal transduction}}, cell-cell recognition, intercellular join…
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Which membrane protein function involves passing substances across the membrane?
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What is the role of membrane proteins in signal transduction?
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How do membrane proteins assist in cell-cell recognition?
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Intercellular joining occurs when membrane proteins form {{c1::junctions}} between adjacent cells.
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Why do membranes have distinct inside and outside faces?
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The asymmetrical distribution of membrane components is established in the {{c1::ER}} and {{c2::Golgi apparatus}}.
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What determines the sidedness of a membrane?
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Membranes have distinct faces because of the {{c1::asymmetrical distribution}} of components.
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The {{c1::ER}} and {{c2::Golgi apparatus}} determine the asymmetrical distribution of membrane components.
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What is the role of vesicles in membrane sidedness?
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The plasma membrane has a {{c1::cytoplasmic}} face and an {{c2::extracellular}} face.
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What property of plasma membranes allows them to regulate molecular traffic?
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Hydrophobic molecules, such as {{c1::hydrocarbons}}, can pass through the membrane {{c2::rapidly}}.
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The plasma membrane controls exchange of materials between the cell and its surroundings, a process called {{c1::selective permeability}}.
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How do polar molecules like sugars move through the plasma membrane?
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What is passive transport?
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What happens at dynamic equilibrium in diffusion?
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Diffusion is the tendency for molecules to {{c1::spread out evenly}} into available space.
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While individual molecules move randomly, a population of molecules shows net movement in {{c1::one direction}} during diffusion.
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What is osmosis?
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What drives the movement of water during osmosis?
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Water diffuses from a region of {{c1::lower solute concentration}} to a region of {{c2::higher solute concentration}}.
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What is tonicity?
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In an {{c1::isotonic}} solution, the solute concentration is the same as inside the cell, so there is {{c2::no net water movement}}.
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In a {{c1::hypotonic}} solution, the solute concentration is lower than inside the cell, so the cell {{c2::gains water}}.
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What happens to a cell in a hypertonic solution?
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Compare isotonic, hypertonic, and hypotonic solutions in terms of water movement.
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What is the role of transport proteins in the membrane?
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What are aquaporins?
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{{c1::Channel proteins}} have a hydrophilic channel that certain molecules or ions can use as a tunnel.
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Aquaporins are transport proteins that help water move across the membrane {{c1::rapidly}}.
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{{c1::Channel proteins}} provide corridors for specific molecules or ions to cross the membrane.
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Ion channels are {{c1::gated}} and open or close in response to a {{c2::stimulus}}.
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What is facilitated diffusion?
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What is the function of aquaporins?
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How does facilitated diffusion differ from simple diffusion?
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What distinguishes active transport from facilitated diffusion?
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What type of proteins perform active transport?
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Why is facilitated diffusion considered passive?
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Active transport requires energy, usually in the form of {{c1::ATP}}.
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In active transport, solutes move {{c1::against}} their concentration gradient, unlike facilitated diffusion, where solutes move {{c2::down}} their gr…
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Voltage is created by differences in the distribution of {{c1::positive and negative ions}}.
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An {{c1::electrogenic pump}} is a transport protein that generates voltage across a membrane.
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The {{c1::proton pump}} is the main electrogenic pump of plants, fungi, and bacteria.
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What is membrane potential?
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What are the two forces that drive ion diffusion across a membrane?
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What is the major electrogenic pump in animal cells?
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What does the electrochemical gradient consist of?
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How do large molecules, like proteins, cross the membrane?
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What happens during exocytosis?
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Compare exocytosis and endocytosis.
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Bulk transport, such as exocytosis and endocytosis, requires {{c1::energy}}.
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In endocytosis, the cell takes in macromolecules by forming {{c1::vesicles}} from the plasma membrane.
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