Notes in Rickets

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Published	10/08/2024	Rickets is caused by a deficiency in {{c1::vitamin D}} or {{c1::calcium}}.
Published	10/08/2024	Vitamin D is a hormone created from {{c1::cholesterol}} by the skin in response to {{c1::UV radiation }}
Published	10/08/2024	Vitamin D is essential in {{c1::calcium}} and {{c1::phosphate}} absorption from the intestines and kidneys.  Vitamin D is also responsible f…
Published	10/08/2024	Other investigation for rickets include: • Low Serum {{c1:: calcium}} • Low Serum {{c1::phosphate}} • High Serum {{c1::alkaline phosphatas…
Published	10/08/2024	{{c1::Breastfed}} babies are at higher risk of vitamin D deficiency compared with {{c1::formula fed}} babies
Published	10/08/2024	Children with vitamin D deficiency can be treated with vitamin D ({{c1::cholecalciferol}}).
Published	10/08/2024	in Hypophosphatemic Rickets Treatment consists of {{c1::Burosumab::anti-FGF-23 agent}}
Published	10/08/2024	Invesitgations for Rickets:Serum {{c1::25-hydroxyvitamin D}}. Less than 25nmol/L can lead to RicketsLow Serum {{c1::Ca2+}}Imaging: {{c1::Xray}} is req…
Published	10/08/2024	Bone deformities that can occur in rickets include:{{c1::Bowing}} of the legs{{c1::Knock}} knees{{c1::Rachitic rosary}}: ends of the ribs expand at th…
Published	10/08/2024	Symptoms of Rickets:• Lethargy• Bone {{c1::pain & deformity}}• Swollen {{c1::wrists}}• Poor growth• {{c1::Dental}} problems• Muscle weakness• Path…
Published	10/08/2024	Inadequate vitamin D leads to a lack of {{c1::calcium}} and {{c1::phosphate}} in the blood. This results in defective bone {{c1::mineralisation}}…
Published	10/08/2024	Patients with malabsorption disorders (e.g. IBD/Coeliac) are {{c1::more::more/less}} likely to have vitamin D deficiency.
Published	10/08/2024	Rickets can also be due to {{c1::hereditary hypophosphataemic rickets}} - which is where the body is resistant to Vit DThe most common form is X-…
Published	10/08/2024	Vitamin D rich Foods: {{c1::oily fish }}{{c1::eggs}}Calcium: {{c1::dairy}} & some green veggies Nutritional supplements
Published	10/08/2024	Rickets is a condition affecting children where there is defective {{c1::bone mineralisation}} leading to inadequate bone formation and therefore…
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