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04 Gram Negative Bacteria
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Published
06/01/2024
What color colonies do lactose-fermenting enteric bacteria yield on MacConkey agar?{{c1::Pink}}
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06/01/2024
{{c1::Neisseria meningitidis::Which species of Neisseria}} has a polysaccharide capsule, which inhibits {{c2::phagocytosis}}
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06/01/2024
{{c1::Neonatal Conjunctivitis}} is an early ({{c3::2}}-{{c3::5}} days) ocular infection seen in neonates due to {{c2::Neisseria gonorrhoeae}} infectio…
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06/01/2024
{{c1::Pseudomonas aeruginosa}} is a gram-negative nosocomial bacterial infection that has respiratory therapy equipment as a risk factor
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06/01/2024
{{c1::Klebsiella pneumoniae::bug}} is a cause of pneumonia that most commonly affects the elderly, alcoholics, and diabetics (due to aspiration)
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06/01/2024
{{c2::Klebsiella pneumoniae}} infection is characterized by a thick mucoid capsule that results in gelatinous, '{{c1::currant jelly}}' sputum
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06/01/2024
{{c1::Pseudomonas aeruginosa}} is a common cause of pneumonia in {{c2::cystic fibrosis}} patients
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06/01/2024
Ammonium magnesium phosphate kidney stones are caused by {{c1::urease}} positive organisms
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06/01/2024
The most common cause of meningitis in teenagers is {{c1::Neisseria meningitidis}} infection
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06/01/2024
Neisseria {{c1::gonorrhoeae}} does not have a polysaccharide capsule
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06/01/2024
What kind of discharge is seen with Gonorrhea? {{c1::Creamy, white, purulent discharge}}
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06/01/2024
Pseudomonas aeruginosa produces {{c1::pyocyanin}}, which generates reactive oxygen species (ROS) to kill competing microbes
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06/01/2024
IgA protease is a virulence factor used by Neisseria that allows bacteria to colonize and adhere to {{c1::mucous membranes}}
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06/01/2024
Neisseria meningitidis/gonorrhoeae are gram {{c1::negative}} {{c1::diplococci::specific}}
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06/01/2024
Moraxella catarrhalis are gram {{c1::negative}} {{c1::diplococci}}
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06/01/2024
Which bacteria produces Blue-green pigments? Due to?{{c1::Pseudomonas aeruginosa; Pyocyanin + Pyoverdin}}
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06/01/2024
{{c1::Pseudomonas::which gram negative rod}} is {{c2::β}}-hemolytic
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06/01/2024
{{c2::Bacteroides fragilis}} is a(n) {{c1::obligate anaerobe::obligate aerobe or anaerobe}} that is typically found in the gut and causes abdominal ab…
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06/01/2024
{{c1::Bacteroides fragilis}} is an anaerobe that can enter abdominal abscesses and is resistant to many antibiotics
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06/01/2024
{{c1::Meningococcemia}} results from an immune reaction to the endotoxin of {{c2::Neisseria meningitidis}}
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06/01/2024
Gram Negative Algorithm:Diplococci {{c1::with::with or without}} maltose metabolism - {{c2::Neisseria meningitidis}}
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06/01/2024
Gram Negative Algorithm:Diplococci {{c1::without::with or without}} maltose metabolism - {{c2::Neisseria gonorrhoeae}}, {{c3::Moraxella}}
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06/01/2024
Gram {{c1::Negative}} Algorithm:{{c1::Coccobacilli}} includes {{c2::H. influenzae}}, {{c2::Pasteurella}}, {{c2::Brucella}}, {{c2::Bordetella pertussis…
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06/01/2024
Gram Negative Algorithm:Bacilli who are fast lactose fermenters include {{c1::Klebsiella}}, {{c1::E. coli}}, {{c1::Enterobacter}}
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06/01/2024
Gram Negative Algorithm:Bacilli who are slow lactose fermenters include {{c1::Citrobacter}}, {{c1::Serratia}}
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06/01/2024
Gram Negative Algorithm:Bacilli who are not lactose fermenters and are Oxidase {{c1::Positive}} - {{c2::Pseudomonas}}
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06/01/2024
Gram Negative Algorithm:Bacilli who are not lactose fermenters and are Oxidase Negative, H2S production on TSI agar {{c1::negative}} - {{c2:…
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06/01/2024
Gram Negative Algorithm:Bacilli who are not lactose fermenters and are Oxidase Negative, H2S production on TSI agar {{c1::positive}} - {{c2::salmonell…
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06/01/2024
Gram Negative Algorithm:Comma-shaped rod, grows at 42°C - {{c1::Campylobacter jejuni}}
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06/01/2024
Gram Negative Algorithm:Comma-shaped rod, grows on alkaline media - {{c1::Vibrio cholerae}}
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06/01/2024
Neisseria spp. contains {{c1::lipooligosaccharides (LOS)}} with strong endotoxin activity
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06/01/2024
Lipooligosaccharide of {{c1::Neisseria}} spp. causes a massive inflammatory response
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06/01/2024
Lipooligosaccharide of Neisseria {{c2::meningitidis}} stimulates {{c1::in}}-creased vascular permeability, resulting in {{c1::thrombocytopenia::platel…
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06/01/2024
Capillary leakage seen in Neisseria {{c1::meningitidis}} infection can result in hypovolemia and {{c2::shock}}
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06/01/2024
The shock and resulting vasoconstriction from Neisseria {{c1::meningitidis}} results in adrenal hemorrhage and ultimately {{c2::Waterhouse-Friderichse…
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06/01/2024
What type of bacteria (gram stain, shape) is Pseudomonas?{{c1::Gram negative rod}}
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06/01/2024
Pseudomonas is known to thrive in {{c1::aquatic}} environments
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06/01/2024
What is the oxidase expression of Pseudomonas aeruginosa?{{c1::Positive}}
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06/01/2024
Pseudomonas aeruginosa is {{c1::catalase}} positive, thus patients with chronic granulomatous disease are susceptible to infection
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06/01/2024
What color pigment is associated with Pseudomonas aeruginosa?{{c1::Blue-green}}
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06/01/2024
Which bacteria is associated with a fruity, grape-like odor?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
What is the oxygen dependency of Pseudomonas aeruginosa?{{c1::Obligate aerobe}}
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06/01/2024
Which gram-negative obligate aerobe often causes nosocomial pneumonia?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
Which gram-negative bacteria is associated with pneumonia in cystic fibrosis patients?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
Pseudomonas causes pneumonia and respiratory failure in {{c1::cystic fibrosis}} patients
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06/01/2024
Which gram-negative bacteria is associated with Diabetic Osteomyelitis?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
What feature of Pseudomonas is anti-phagocytic?{{c1::Bacterial capsule}}
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06/01/2024
Which gram-negative bacteria is associated with wound and burn infections?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
{{c1::Ecthyma Gangrenosum}} is a cutaneous disorder caused by Pseudomonas spp. that is described as rapidly progressive, necrotic cutaneous lesions
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06/01/2024
Black necrotic skin lesions seen in {{c2::Pseudomonas}} patients are indicative of {{c1::ecthyma gangrenosum}}
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06/01/2024
Which gram-negative bacteria is associated with Otitis Externa (swimmer's ear)?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
Which exotoxin from Pseudomonas aeruginosa functions to inactivate EF-2 via ADP-Ribosylation?{{c1::Exotoxin A}}
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06/01/2024
Which gram-negative rod produces an exotoxin that ADP-ribosylates EF-2?{{c1::Pseudomonas aeruginosa}}
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06/01/2024
Exotoxin A causes {{c1::ADP-ribosylation}} of {{c2::EF-2 (elongation factor-2)}}, thus inhibiting protein synthesis
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06/01/2024
Which protein found in Pseudomonas aeruginosa functions to generate ROS that kill competing microbes?{{c1::Pyocyanin}}
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06/01/2024
What is the gram stain of Yersinia?{{c1::gram negative}}
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06/01/2024
What is the shape of Yersinia?{{c1::Coccobacillus}}
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06/01/2024
Yersinia pestis is {{c1::encapsulated}}, protecting the bacteria from phagocytosis
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06/01/2024
What is the cause of Bubonic Plague?{{c1::Yersinia pestis}}
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06/01/2024
How is Bubonic Plague (Yersinia pestis) transmitted?{{c1::Fleas}}
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06/01/2024
What animals are the reservoir for Yersinia pestis?{{c1::Rats; Prairie Dogs::2}}
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06/01/2024
Yersinia {{c2::pestis (plague)}} first spreads to the {{c1::lymph nodes}}, forming characteristic {{c1::buboes}}
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06/01/2024
Yersinia pestis (plague) often escapes the lymph nodes to produce {{c1::septicemia}} and widespread {{c2::necrosis}} of the organs
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06/01/2024
The {{c1::YOPS (Yersinia assoc. outer proteins)}} are secreted via a(n) {{c2::type III}} secretion system in Yersinia {{c3::spp.}}
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06/01/2024
Yersinia spp. secretes {{c1::YOPS}}, which cause macrophage/neutrophil dysfunction by inhibiting phagocytosis and cytokine production
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06/01/2024
The three major causes of nosocomial infections are {{c1::Klebsiella}}, {{c2::Enterobacter}}, and {{c3::Serratia}}
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06/01/2024
Klebsiella, Enterobacter, and Serratia commonly cause nosocomial {{c1::pneumonia}} and {{c1::UTIs}}
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06/01/2024
{{c2::Klebsiella}}, Enterobacter, and Serratia are all {{c1::lactose}} fermenters
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06/01/2024
Klebsiella, Enterobacter, and Serratia stain {{c1::pink}} on {{c2::MacConkey}} agar
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06/01/2024
Is Enterobacter motile?{{c1::Yes}}
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06/01/2024
Klebsiella can be remembered by its "three A's"; {{c1::alcoholics}}, {{c2::aspiration}} and {{c3::abscesses}}
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06/01/2024
Does Klebsiella have a capsule?{{c1::Yes}}
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06/01/2024
Patients with Klebsiella pneumoniae will cough up a(n) {{c1::pink, currant jelly}} sputum
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06/01/2024
Which of the common gram-negative nosocomial infections (Klebsiella, Serratia, Enterobacter) is urease-positive?{{c1::Klebsiella}}
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06/01/2024
What is the oxygen dependency of Klebsiella?{{c1::Facultative anaerobe}}
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06/01/2024
Is Salmonella spp. motile?{{c1::Yes}}
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06/01/2024
Salmonella spp. produces {{c2::hydrogen sulfide (H2S)}}, which appears as {{c1::black}} colonies on Hektoen enteric agar
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06/01/2024
Does Salmonella have a capsule?{{c1::Yes}}
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06/01/2024
Does Enterobacter have a capsule?{{c1::No}}
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06/01/2024
The reservoir for Salmonella {{c1::enteritidis}} is chicken
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06/01/2024
Chronic carriers of Salmonella {{c2::typhi}} carry the infection in their {{c1::gallbladder::organ}}
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06/01/2024
Which strain of Salmonella causes typhoid fever?{{c1::Salmonella typhi}}
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06/01/2024
Salmonella {{c2::typhi}} can present with abdominal pain with '{{c1::rose}} spots' cutaneously
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06/01/2024
Salmonella {{c2::typhi}} can cause constipation or '{{c1::pea soup}}' diarrhea
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06/01/2024
A type {{c1::III}} secretion system detects eukaryotic cells and secretes a protein to help with infectivity
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06/01/2024
Salmonella spp. contains a(n) {{c1::type III}} secretion system that acts as a virulence factor
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06/01/2024
Humans are the only reservoir for Salmonella {{c1::typhi}}
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06/01/2024
Is Shigella motile?{{c1::No}}
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06/01/2024
Shigella is acid-{{c1::stable::stable or labile}}
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06/01/2024
Shigella spp. uses host cell {{c1::actin filaments}} to spread from cell to cell
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06/01/2024
Shigella causes {{c1::bloody::watery or bloody}} diarrhea
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06/01/2024
Shigella causes a(n) {{c1::inflammatory}} diarrhea, with the presence of {{c2::blood}} and {{c2::leukocytes}}
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06/01/2024
Shigella {{c2::dysenteriae}} can produce a shiga toxin that leads to {{c1::hemolytic-uremic}} syndrome
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06/01/2024
Hemolytic uremic syndrome (HUS) from Shigella dysenteriae results when shiga toxin damages the {{c1::glomerulus}}, activating {{c1::platelets}}
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06/01/2024
Damage to the glomerulus in Shigella-induced HUS results in platelet aggregation, {{c1::decreasing}} the platelet count when {{c1::microthombi}} form
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06/01/2024
The microthrombi of hemolytic uremic syndrome (HUS) cause {{c1::red blood}} cell lysis
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06/01/2024
Shiga toxin binds to the {{c1::60s subunit of ribosomes}}, inhibiting {{c2::protein}} synthesis
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06/01/2024
Shigella secretes effector proteins via a(n) {{c1::type III}} secretion system
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06/01/2024
Does E. coli ferment lactose?{{c1::Yes}}
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06/01/2024
Does Shigella ferment lactose?{{c1::No}}
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06/01/2024
Does Salmonella ferment lactose?{{c1::No}}
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06/01/2024
E. coli will stain {{c1::pink}} on MacConkey agar
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06/01/2024
Does Shigella have a capsule?{{c1::no}}
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06/01/2024
Does E. coli have a capsule?{{c1::Yes}}
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06/01/2024
Which gram negative enteric bacteria is catalase positive?{{c1::E. coli}}
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06/01/2024
{{c2::Enterohemorrhagic}} E. coli is transmitted by eating {{c1::undercooked beef}}
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06/01/2024
Which form of E. coli presents with dysentery (bloody, mucousy diarrhea)?{{c1::Enterohemorrhagic E. coli (EHEC)}}
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06/01/2024
Which bacteria produces Shiga-like toxin (verotoxin)?{{c1::Enterohemorrhagic E. coli (EHEC)}}
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06/01/2024
The shiga-like toxin (SLT) of Enterohemorrhagic E. coli kills {{c1::enterocytes::cell type}}
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06/01/2024
{{c2::Enterohemorrhagic}} E. coli can result in glomerular damage and thus {{c1::hemolytic uremic syndrome (HUS)}}
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06/01/2024
Campylobacter jejuni grows best at {{c1::42°C::temperature}}
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06/01/2024
Campylobacter jejuni is {{c1::microaerophilic}}, meaning it grows best at lower O2 than atmosphere
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06/01/2024
The reservoir of Campylobacter jejuni is {{c1::poultry}}, cattle, and dogs
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06/01/2024
{{c3::Campylobacter jejuni}} is a curved bacteria that presents with {{c1::inflammatory}} diarrhea that is initially {{c2::watery}} and {{c2::ill…
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06/01/2024
What is the shape and stain of Campylobacter jejuni?{{c1::Gram negative curved rod}}
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06/01/2024
{{c2::Campylobacter jejuni}}, Vibrio cholerae and Helicobacter pylori are all curved rods that are {{c1::oxidase}} positive
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06/01/2024
Which curved gram negative rod is invasive and can thus cause bacteremia?{{c1::Campylobacter jejuni}}
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06/01/2024
{{c1::Campylobacteri jejuni}} is a curved bacteria that can cause {{c2::reactive arthritis}}, a spondyloarthropathy
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06/01/2024
{{c2::Campylobacter jejuni}} is a curved bacteria that can precede {{c1::Guillain-Barré syndrome}}, characterized by a(n) {{c3::ascending::ascend…
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06/01/2024
Treatment for Campylobacter jejuni infection includes erythromycin or {{c1::ciprofloxacin}}
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06/01/2024
Which gram-negative enteric bacteria causes rice water stools?{{c1::Vibrio cholerae}}
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06/01/2024
Vibrio cholerae causes profuse {{c1::watery}} diarrhea with visible flakes of {{c2::mucous}} and {{c2::epithelial}} cells
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06/01/2024
What is the route of transmission of Vibrio cholerae?{{c1::Fecal-oral}}
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06/01/2024
{{c1::Vibrio cholerae}} is a curved bacteria that uses {{c2::fimbriae}} to attach to the intestinal mucosa
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06/01/2024
Vibrio cholerae produces {{c4::cholera}} toxin, which {{c3::ADP-ribosylates}} and {{c2::activates}} {{c1::Gs}} resulting in a(n) {{c2::increase}} in {…
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06/01/2024
An increase in cAMP from cholera toxin opens the CFTR channel, {{c2::increasing}} {{c1::Cl-}} ion secretion into the intestinal lumen
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06/01/2024
Increased Cl- secretion from CFTR due to cholera toxin results in decreased {{c1::Na+}} absorption, thus {{c1::H2O}} diffuses into the intestinal lume…
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06/01/2024
Vibrio cholerae grows on {{c1::alkaline}} media, as it prefers {{c1::basic}} environments
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06/01/2024
{{c1::Vibrio cholerae}} is a bacteria that grows flat, {{c2::yellow}} colonies on {{c3::TCBS}} agar
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06/01/2024
Vibrio cholerae also produces {{c1::mucinase}} to digest the protective mucous coat around intestinal cells
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06/01/2024
Klebsiella can result in {{c1::abscess}} formation in the lung
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06/01/2024
Salmonella enteritidis produces an inflammatory diarrhea, with {{c1::leukocytes}} present in stool
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06/01/2024
What RBC morphology is present in hemolytic uremic syndrome (HUS)?{{c1::Schistocytes (helmet cells)}}
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06/01/2024
Does Enterobacter ferment lactose? {{c1::Yes}}
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06/01/2024
Does Serratia ferment lactose? {{c1::Yes}}
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06/01/2024
What is the gram stain of Haemophilus influenzae?{{c1::Gram negative}}
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06/01/2024
What is the shape of Haemophilus influenzae?{{c1::Coccobacillus}}
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06/01/2024
What agar is used to grow Haemophilus influenzae?{{c1::Chocolate agar}}
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06/01/2024
Factors {{c1::V (NAD+)}} and {{c1::X (hematin)}} are added to chocolate agar to grow Haemophilus influenzae
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06/01/2024
What is the primary method of transmission of Haemophilus influenzae?{{c1::Aerosol}}
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06/01/2024
Haemophilus influenzae classically causes {{c1::epiglottitis}}, which can be described as '{{c2::cherry-red}}' on gross appearance
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06/01/2024
Haemophilus influenzae is a common cause of {{c1::otitis media::ear pathology}} in children
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06/01/2024
Meningitis is only caused by {{c2::Haemophilus influenzae}} when the bacteria is in its {{c1::type B capsular}} form
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06/01/2024
Haemophilus influenzae infection consequences can be remembered by the mnemonic hAEMOPhilus:A{{c5::rthritis (septic)}}E{{c1::piglottitis (cherry red a…
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06/01/2024
What strain of Haemophilus influenzae is a vaccine available for?{{c1::Type B (meningitis causing)}}
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06/01/2024
Epiglottitis with a '{{c1::thumb-print}}' sign on imaging is classic for {{c2::Haemophilus influenzae}} infection
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06/01/2024
Haemophilus influenzae is able to colonize the {{c2::upper respiratory}} tract due to {{c1::IgA protease::virulence factor}}
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06/01/2024
What is the gram stain of Brucella?{{c1::Gram negative}}
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06/01/2024
What is the shape of Brucella?{{c1::Coccobacillus}}
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06/01/2024
What are the reservoirs of the Brucella spp. strains?{{c1::Farm animals (cows, pigs, goats, sheep)}}
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06/01/2024
Direct transmission of Brucella spp. results from contact with {{c1::farm animals (cows, pigs, goats, sheep are the reservoirs)}}
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06/01/2024
Indirect transmission of Brucella spp. results from ingestion of {{c1::unpasteurized dairy products (milk, cheese)}}
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06/01/2024
Brucellosis due to Brucella spp. presents with {{c1::undulant fever}}, anorexia, and fatigue
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06/01/2024
Which enteric gram negative coccobacillus has a bipolar (safety-pin) staining pattern?{{c1::Yersinia spp.}}
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06/01/2024
Which type of necrosis is associated with bacterial (e.g. Klebsiella) lung abscesses?{{c1::Liquefactive}}
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06/01/2024
Which cause of sterile urethritis shows up on staining as gram (-) diplococci?{{c1::N. gonorrhoeae}}
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06/01/2024
In addition to ingesting undercooked poultry, interacting with {{c1::household pets}} can predipose to Campylobacter
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06/01/2024
What is the treatment for Campylobacter gastroenteritis?{{c1::Supportive care (e.g. rehydration)}}
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06/01/2024
What is the oxygen dependency of Moraxella catarrhalis?{{c1::obligate aerobe}}
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06/01/2024
Moraxella catarrhalis is associated with causing {{c1::COPD}} exacerbations, {{c2::otitis media}} in children, and {{c3::sinusitis}}
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06/01/2024
Bacteroides fragilis is part of the normal {{c1::colonic}} flora
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06/01/2024
Cholera toxin causes diarrhea by {{c1::activating::activating/inhibiting}} {{c1::CFTR::target}}
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06/01/2024
Cholera toxin acts via {{c1::Gs}}-type receptor, so the second messenger is {{c1::cAMP}}
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06/01/2024
What is the oxidase expression of Enterobacterales?{{c1::Negative}}
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06/01/2024
What color pigment is associated with Serratia marcescens?{{c1::Red}}
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06/01/2024
Does enterohemorrhagic E. coli (EHEC) typically present with fever?{{c1::No}}
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06/01/2024
What is the natural reservoir of enterohemorrhagic E. coli (EHEC)?{{c1::GI tract of cattle}}
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06/01/2024
If patient has recurrent Salmonella bacteremia, you should suspect that they might have underlying {{c1::AIDS}}
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06/01/2024
A subset of Shiga toxin-producing E. coli (STEC) that also has the LEE pathogenicity island is called {{c1::enterohemorrhagic (EHEC)}} E. coli
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06/01/2024
EHEC and other forms of STEC are equally likely to produce {{c1::HUS::sx}}, but EHEC is more likely to produce {{c1::dysentery::sx}}
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06/01/2024
Yersinia pestis usually spreads from fleas to people, but when it does spread person-to-person, what is its route of transmission?{{c1::Droplet}}
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06/01/2024
What is the most serious presentation of Yersinia pestis infection?{{c1::Pneumonic}}
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06/01/2024
What is the most common presentation of Yersinia pestis infection?{{c1::Bubonic}}
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06/01/2024
This sputum Gram stain shows {{c1::Moraxella catarrhalis}} infection
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Last Update
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