Notes in 02_Motor Neurone Disease

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Published	02/10/2024	{{c1::Motor neurone disease}} is a {{c2::progressive, ultimately fatal condition where the motor neurones stop functioning with no sensory involvement…
Published	02/10/2024	Presentation of {{c2::Motor Neurone Disease (MND)}} {{c1::Weakness (usually distal to proximal progression)}} {{c1::UMN signs (e.g. hyperreflexia, spa…
Published	02/10/2024	Presentation of {{c2::Upper}} Motor Neurone Disease {{c1::Increased muscle tone (Spasticity)}} {{c1::Hyperreflexia}} {{c1::Positive Babinski’s Si…
Published	02/10/2024	Presentation of {{c2::Lower}} Motor Neurone Disease {{c1::Flaccidity}} {{c1::Hyporeflexia}} {{c1::Muscle wasting/atrophy}} {{c1::Fasciculations (…
Published	02/10/2024	Diagnosis of Motor Neurone Disease (MND) {{c1::Clinical Symptoms (UMN + LMN Signs) without any sensory signs}} {{c1::Nerve conduction studies and Elec…
Published	02/10/2024	{{c1::Nerve conduction studies}} and {{c1::Electromyography}} are diagnostic tests of Motor Neurone Disease showing denervation
Published	02/10/2024	First-line Management of Motor Neurone Disease is {{c1::Riluzole (Glutamate antagonist)}} which prolongs life expectancy by months
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