Notes in 04 Inflammatory Skin Disorders II

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Published	01/12/2024	The dermatitis herpetiformis that arises with celiac disease is due to {{c1::IgA}} deposition at the tips of the dermal papillae
Published	01/12/2024	Coccidioidomycosis can also cause {{c1::erythema nodosum}}, characterized by painful red nodules, typically on the shins
Published	01/12/2024	{{c1::Acne}} (pictured below) varies clinically but typically presents with pustules, papules, comedones, cysts, or scarring
Published	01/12/2024	In acne, keratin blocks the outflow tract of the sebaceous gland causes inflammation and comedo wall rupture, causing {{c1::comedones}}
Published	01/12/2024	Acne is most often on the {{c1::face}} and {{c1::upper trunk}} because these areas have well-developed sebaceous glands
Published	01/12/2024	{{c1::Acne fulminans}} is the most severe form of acne and comes with significant scarring
Published	01/12/2024	What condition is shown below?{{c1::Acne}}
Published	01/12/2024	{{c1::Inflammatory::inflammatory vs. non-inflammatory}} acne presents with papules, pustules, nodules, and/or cysts
Published	01/12/2024	What condition is this?{{c1::Acne}}
Published	01/12/2024	First line treatment of acne is {{c1::topical retinoids}}, but if these aren't strong enough, you can give {{c1::oral retinoids (i.e. acutan…
Published	01/12/2024	Antibiotics can be given to treat acne as they {{c1::decrease}} inflammation
Published	01/12/2024	{{c1::Rosacea}} is a skin condition defined by facial erythema, telangiectasis, flushing, papules, pustules, but no comedones
Published	01/12/2024	What skin condition is this?{{c1::Ocular rosacea}}
Published	01/12/2024	Some environmental triggers of {{c1::rosacea::skin condition}} include heat, alcohol, spicy foods, UV light. As such, the main treatment is to {{c2::a…
Published	01/12/2024	These patients come into your clinic because they are concerned about their skin condition, but they say that their face doesn't itch or bother them. …
Published	01/12/2024	Topical medications, like antibiotics and selective alpha-adrenergic agonists, are used to treat rosacea, but if these don't work, we move to {{c1::sy…
Published	01/12/2024	Pilonidal cysts typically occur in the 2nd decade of life in {{c1::hirsute (hairy) males}}
Published	01/12/2024	Erythema nodosum is also associated with various drugs such as {{c1::OCPs}}, sulfonamides, and penicillin
Published	01/12/2024	Erythema nodosum is {{c1::bi}}lateral, tender and affects the {{c1::pretibial}} areas
Published	01/12/2024	Erythema nodosum is associated with {{c1::sarcoidosis}} and {{c1::inflammatory bowel}} disease among other systemic disorders and infections
Published	01/12/2024	Pemphigus is characterized by intra-{{c1::epidermal}} blisters which are fragile
Published	01/12/2024	This immunofluorescence of the epidermis shows what conditions?{{c1::Pemphigus}}
Published	01/12/2024	Pemphigus {{c1::vulgaris}} shows painful mucosal involvement in almost all patientsPemphigus {{c1::foliaceus}} does not show mucosal involvement
Published	01/12/2024	{{c1::Paraneoplastic}} pemphigus shows intractable stomatitis (lots of pain and inflammation around the mouth)  and is associated with under…
Published	01/12/2024	What type of pemphigus is this?{{c1::Pemphigus foliaceus}}
Published	01/12/2024	To treat pemphigus give {{c1::systemic corticosteroids}}, but you can't keep them on this forever, so many physicians now give {{c2::rituximab}}
Published	01/12/2024	{{c1::Bullous pemphigoid}} is the most common autoimmune sub-epidermal blistering disease and presents with tense blisters
Published	01/12/2024	Bullous pemphigoid presents with tense blisters because the autoantibodies target {{c1::dermal-epidermal}} cohesion
Published	01/12/2024	Bullous pemphigoid is significantly associated with {{c1::neurological}} disorders and can be caused by {{c2::systemic}} medications (classically diur…
Published	01/12/2024	c2fb67535084462da64af7e30dcc0700-oa-1
Published	01/12/2024	To treat bullous pemphigoid that is localized/mild -> give {{c1::topical corticosteroids}} or {{c1::antibiotics}} (tetracycline) To treat bull…
Published	01/12/2024	Dermatitis herpetiformis has a compliex pathogenesis but involves {{c1::TG2}} and {{c1::TG3}}
Published	01/12/2024	Dermatitis herpetiformis responds to {{c1::gluten restriction::diet change}}
Published	01/12/2024	Dermatitis herpetiformis presents with vesicles and papules that are intensely {{c1::pruritic}} and typically on the extensor surfaces
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