Notes in 12 Unusual Pathogens

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Status	Last Update	Fields
Published	07/30/2024	{{c1::Legionella pneumophila::Bacteria}} uses {{c2::protein}} instead of carbohydrates for energy
Published	07/30/2024	Legionella pneumophila is {{c1::a::ana/a}}erobic
Published	07/30/2024	Legionella pneumophila Slide Morphology: {{c1::gram (-), intracellular bacilli (but it stains poorly)}}
Published	07/30/2024	Legionella pneumophila Location: {{c1::Ubiquitous, warm & moist environment; prefers aquatic habitat}}
Published	07/30/2024	{{c1::Legionella pneumophila::Bacteria}} can multiply in free-living amoebas
Published	07/30/2024	Legionella pneumophila MOT: {{c1::Inhalation from environmental sources. NO PERSON-TO-PERSON transmission}}
Published	07/30/2024	{{c1::Metalloprotease}} - Virulence factor of Legionella pneumophila w/ hemolytic and cytotoxic activity
Published	07/30/2024	{{c1::Mip Protein}} - Virulence factor of Legionella pneumophila for macrophage invasion and promotes adherence and its phagocytosis
Published	07/30/2024	Legionella pneumophila Important Associated Diseases: {{c1::Legionnaire's Disease, Pontiac Fever::2}}
Published	07/30/2024	Legionnaire's Disease Clinical Findings:{{c1::Febrile illness of short durationSevere rapidly progressive illness (fever, chills, malaise, dry cough, …
Published	07/30/2024	Pontiac Fever Clinical Findings:{{c1::Fever, chills, myalgia, malaise, headacheDizziness, photophobia, neck stiffness and confusionLess prominent resp…
Published	07/30/2024	[QC] Self-limiting1. Legionnaire's Disease2. Pontiac Fever{{c1::B}}
Published	07/30/2024	Legionnaire's disease most affects px w/ {{c1::compromised immune systems::demographic}}
Published	07/30/2024	Why is Legionella pneumophila hard to gram stain?{{c1::Branched-chain cellular fatty acids on the cell wall}}
Published	07/30/2024	What do you use as a stains for Legionella pneumophila?Gram Counterstain: {{c1::0.1% basic fuchsin}}Silver Stain: {{c1::Silver stain}}
Published	07/30/2024	Legionella pneumophila Media: {{c1::Buffered charcoal yeast extract (BCYE) agar (with L-cysteine, α-ketoglutarate, iron at pH 6.9)}}
Published	07/30/2024	Legionella pneumophila Incubation Temperature: {{c1::35-37}} °C
Published	07/30/2024	Legionella pneumophila grows in {{c1::14 days::time frame}}
Published	07/30/2024	Legionella pneumophila Colony Morphology: {{c1::round or flat with entire edges; colorless to iridescent pink or blue; translucent or speckled}}
Published	07/30/2024	Legionella pneumophila Important Biochemical Tests:Oxidase ({{c1::+}})Catalase ({{c1::+}}){{c1::Hydrolyzes hippurateProduces gelatinase and beta-…
Published	07/30/2024	Legionella pneumophila Diagnosis:{{c1::Urine antigen test for serogroup 1 for early course of infectionPCR - Mip & 16SrRNA genes}}
Published	07/30/2024	Legionella pneumophila DOC: {{c1::Macrolides, Quinolones, Tetracyclines::3 classes}}
Published	07/30/2024	Best prevention of Legionella infection is {{c1::water treatment}}
Published	07/30/2024	Bartonella elizabethae, B. vinsonii subsp. berkhofii, B. vinsonii subsp. arupensis, B. koehlerae, B. alsatica Important Associated Diseases:…
Published	07/30/2024	Bartonella Slide Morphology: {{c1::Gram (-), Facultative intracellular bacilli}}
Published	07/30/2024	Bartonella Stain: {{c1::Warthin-Starry Silver Impregnation Stain}}
Published	07/30/2024	Bartonella bacilliformis Epidemiology: {{c1::American Andes, Peru, Columbia, Ecuador}}
Published	07/30/2024	Bartonella bacilliformis Vector: {{c1::Lutzomyia sandflies}}
Published	07/30/2024	{{c1::Deformin}} - Virulence factor of {{c2::Bartonella bacilliformis}} that causes indentation on RBC membranes
Published	07/30/2024	Bartonella bacilliformis Important Associated Diseases: {{c1::Initial: Oroya Fever, Chronic: Verruga Peruana (Carrison's Disease)::2}}
Published	07/30/2024	Oroya Fever Clinical Findings:{{c1::Acute Hemolytic Bacteremia → Anemia → HepatosplenomegalyHemorrhage into the lymph nodesInvades endothelial cell an…
Published	07/30/2024	Verruga Peruana (Carrison's Disease) Clinical Findings:{{c1::Vascular nodular skin lesions appearing in successive cropsGranulomasChronic vasoprolifer…
Published	07/30/2024	Bartonella bacilliformis Diagnosis: {{c1::Stained blood smears and blood culture}}
Published	07/30/2024	Verruga Peruana (Carrison's Disease) occurs {{c1::2-8 weeks}} after Oroya fever and lasts for {{c1::1 year}}
Published	07/30/2024	Bartonella bacilliformis Media: {{c1::Semisolid nutrient agar with 10% rabbit serum and 0.5 hemoglobin}}
Published	07/30/2024	Bartonella bacilliformis DOC: {{c1::Ciprofloxacin, doxycycline, macrolides, TMP-SMX x 10 days. Chloramphenicol x 14 days}}
Published	07/30/2024	Aside from antibiotics, what other ancillary treatments do you give in px with Bartonella bacilliformis?{{c1::Blood transfusion}}
Published	07/30/2024	Bartonella henselae Important Associated Diseases: {{c1::Cat scratch disease}}
Published	07/30/2024	{{c2::Cat scratch disease}} Clinical Findings:{{c1::Low grade fever and lymphadenopathy (1-3 weeks after contact with cat - scratch, lick, bite)Primar…
Published	07/30/2024	Cat scratch disease lasts for {{c1::a short time because it's benign and self-limiting}}
Published	07/30/2024	Bartonella henselae Diagnosis:{{c1::Biopsy of capllary walls near follifular hyperplasia or microabscesses w/ small pleomorphic g (-) rods}}
Published	07/30/2024	Bartonella henselae usually affects px with {{c1::competent immune systems}}
Published	07/30/2024	Bartonella henselae DOC: {{c1::Just analgesics}}
Published	07/30/2024	Bartonella quintana Important Associated Diseases: {{c1::Trench/Quintan Fever, Bacillary Angiomatosis::2}}
Published	07/30/2024	Bartonella quintana Vector: {{c1::Human body louse}}
Published	07/30/2024	Trench Fever Clinical Findings:{{c1::Fever, headache, malaise, restlessness and shin painOrganisms are released in the blood 3-5 days with each episod…
Published	07/30/2024	Bartonella quintana Media: {{c1::BAP, CAP under 5% CO2}}
Published	07/30/2024	Bartonella quintana microcolonies appear after {{c1::21}} days of incubation at {{c1::37}} C
Published	07/30/2024	Bartonella quintana DOC: {{c1::Antibiotics in general will kill it}}
Published	07/30/2024	Bacillary Angiomatosis Etiology: {{c1::Bartonella quintana, Bartonella henselae::2}}
Published	07/30/2024	Bacillary Angiomatosis Clinical Findings:{{c1::Vascular proliferative diseaseLymph nodesEnlarged red (cranberry-like) papule surrounded by scale and e…
Published	07/30/2024	Bacillary Angiomatosis Histopathologic Findings:{{c1::Well- circumscribed lesions with lobular capillary proliferation and round, open vessels with cu…
Published	07/30/2024	Bacillary Angiomatosis is usually seen in px w/ {{c1::HIV/AIDS or the immunocompromised}}
Published	07/30/2024	Bacillary Angiomatosis DOC: {{c1::Erythromycin}}
Published	07/30/2024	Streptobacillus moniliformis is {{c1::a::ana/a}}erobic
Published	07/30/2024	Streptobacillus moniliformis is gram ({{c1::-}})
Published	07/30/2024	Streptobacillus moniliformis Media: {{c1::Agar SPECIFICALLY w/ serum protein, egg yolk, or starch at 37 C}}
Published	07/30/2024	Streptobacillus moniliformis Important Associated Diseases: {{c1::Rat Bite Fever, Haverhill Fever}}
Published	07/30/2024	Haverhill Fever MOT: {{c1::Ingestion of contaminated milk}}
Published	07/30/2024	Haverhill Fever Clinical Findings:{{c1::PolyarthritisBlotchy and Petechial Rashes::2}}
Published	07/30/2024	Rat Bite Fever Clinical Findings:{{c1::PolyarthritisBlotchy and Petechial RashesSeptic Fever, bacteremia, endocarditis, abscesses::3}}
Published	07/30/2024	Rat Bite Fever Diagnosis:{{c1::blood, joint fluid, pus for culture; mouse inoculation, serum agglutination test}}
Published	07/30/2024	Streptobacillus moniliformis DOC: {{c1::Penicillin, 3rd Generation Cephalosporins, Fluoroquinolones}}
Published	07/30/2024	Trophyrema whipplei is gram ({{c1::+}})
Published	07/30/2024	Trophyrema whipplei usually affects px w/ {{c1::age 50 y/o and male and history of soil and animal exposure}}
Published	07/30/2024	Trophyrema whipplei Location in Humans: {{c1::SI and mesenteric LNs}}
Published	07/30/2024	{{c2::Trophyrema whipplei}} Infection Clinical Findings:{{c1::Arthritis, Arthralgia → diarrhea, abdominal pain, weight loss, migratory polyarthra…
Published	07/30/2024	Trophyrema whipplei Media: {{c1::eukaryotic cells (human fibroblasts, deactivated peripheral blood monocytes)}}
Published	07/30/2024	Trophyrema whipplei Diagnosis:{{c1::Stool, saliva, dental plaque, gastric juiceIntestinal tissue biopsy: PAS-positive vacuoles and bacilli inside macr…
Published	07/30/2024	Trophyrema whipplei DOC: {{c1::TMP-SXT, macrolides, aminoglycosides, tetracycline, and penicillin}}
Published	07/30/2024	{{c1::Tetracycline}} use in Trophyrema whipplei infection is associated w/ serious relapses
Published	07/30/2024	Aside from antibiotics, what other ancillary treatments do you give in px with Trophyrema whipplei?{{c1::Colchicine}}
Status	Last Update	Fields