Notes in 03SignalTransduction

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Published 07/30/2024 {{c1::Juxtacrine or Contact-dependent signaling}} - stimulation of neighboring cells or one cell and the matrix of another cell
Published 07/30/2024 4 types of chemicals which act as ligands:{{c1::AminesPeptides and proteinsSteroidsOther small molecules}}
Published 07/30/2024 2 classes of nuclear/intracellular receptors:{{c1::Receptors for steroid hormonesReceptors for thyroid hormones, retinoic acid, and vitamin D}}
Published 07/30/2024 Cytoplasmic receptors are frequently complexed to {{c1::Heat-shock proteins::chaperone proteins}}
Published 07/30/2024 {{c1::Nuclear}} receptors hace transactivation domains
Published 07/30/2024 Classes of Catalytic Receptors{{c1::Receptor Tyrosine Kinases, Receptors serine/threonin kinases}} - Phosphorylate tyrosine residues on themselves and…
Published 07/30/2024 G protein receptor polypeptide chains span the plasmalemma {{c1::7}} times
Published 07/30/2024 GPCR subunit that binds and hydrolyzes GTP: {{c1::Alpha}}
Published 07/30/2024 GPCR subunit that anchors the GPCR complex to the membrane: {{c1::Alpha and Gamma}}
Published 07/30/2024 The G protein is in an active state when it is bound to G{{c1::T}}P
Published 07/30/2024 {{c1::Ras}} - GTPase that relays membrane signal to the nucleus
Published 07/30/2024 {{c1::Rho}} - GTPase that rearrangement of actin cytoskeleton
Published 07/30/2024 {{c1::Rab and Arf}} - GTPase that regulates vesicle trafficking
Published 07/30/2024 {{c1::Ran}} - GTPase that regulates nucleocytoplasmic transporting
Published 07/30/2024 {{c1::Cleavage-Activated}} Receptors - Transmembrane proteins which undergo regulated intramembranous proteolysis
Published 07/30/2024 In the arachidonic acid pathway, the alpha subunit activates {{c1::phospholipase A2}}
Published 07/30/2024 Arachidonic acid is the substrate for 3 pathways:{{c1::Cyclooxygenase pathwayLipoxygenase pathwayEpoxygenase pathway}}
Published 07/30/2024 The Cyclooxygenase pathway produces{{c1::ThromboxanesProstaglandinsProstacyclins}}
Published 07/30/2024 The 5-Lipoxygenase pathway produces{{c1::HETE (5-Hydroxyeicosatetraenoic acid)Leukotrienes}}
Published 07/30/2024 The Epoxygenase pathway produces{{c1::Eicosanoidsother HETEs and cis-epoxyeicosatrienoic acid (EETs)}}
Published 07/30/2024 The {{c1::Rho}} monomeric G protein regulates actin cytoskeletal organization, cell cycle progression, and gene expression
Published 07/30/2024 The {{c1::Rab and Arf}} monomeric G protein regulates intravesicular transport and trafficking of proteins between organelles in secretory and endocyt…
Published 07/30/2024 The {{c1::Ran}} monomeric G protein regulates nucleocytoplasmic transport of RNA and proteins
Published 07/30/2024 The {{c1::Ras}} monomeric G protein cell division, proliferation, and death
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