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Case 1: Anemias and Hemoglobinopathies
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Published
12/13/2023
This picture shows {{c1::basophilic stippling::RBC abnormality}}, which is indicative of {{c2::lead poisoning}} or {{c2::thalassemia}}
Published
12/13/2023
What hematologic abnormality is shown in the image below?
Published
12/13/2023
Lead (Pb) poisoning leads to inhibition of the enzymes {{c1::δ-aminolevulinic acid dehydratase}} and {{c2::ferrochelatase}} (heme synthesis)
Published
12/13/2023
{{c1::Anemia}} is defined as a reduction in circulating red blood cell (RBC) mass
Published
12/13/2023
What measurement is used to classify anemia as microcytic, normocytic, or macrocytic? {{c1::Mean corpuscular volume (MCV)}}
Published
12/13/2023
{{c2::Micro}}cytic {{c2::sideroblastic}} anemia may be caused by {{c1::lead}} poisoning
Published
12/13/2023
{{c2::α}}-thalassemia is usually due to gene {{c1::deletions}}
Published
12/14/2023
{{c3::β}}-thalassemia is most commonly seen in individuals of {{c2::Mediterranean}} descent
Published
12/13/2023
Sickle cell anemia occurs due to a point mutation that substitutes {{c1::glutamic acid}} (hydrophilic) with {{c1::valine}} (hydrophobic)
Published
12/13/2023
The sickle cell (HbS) allele is carried by {{c1::8 - 10}}% of African Americans
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