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Malaria: Lifecycle & Epidemiology
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Published
01/06/2024
What are the different species of Plasmodium that cause malaria in humans?
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Mosquito stagesFemale mosquito feeds on {{c1::uninfected}} human{{c1::Gametes}} from blood fuse in mosquito stomach -> form {{c1::oo…
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{{c1::Plasmodium falciparum}} is the most widespread and the major cause of severe cases of malaria. It is predominantly found in sub-Saharan Afr…
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{{c1::Plasmodium vivax}} and {{c1::Plasmodium ovale}} can form {{c2::hypnozoites}} which are dormant forms of the parasite that reside …
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{{c1::Plasmodium malariae}} has a longer life cycle in the human bloodstream and chronic infections can persist for many years
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{{c1::Plasmodium knowlesi}} can infect humans through a bite from infected mosquitoes that have previously bitten infected macaque monkeys. …
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Describe the different fever patterns caused by plasmodium species Tertian malaria = fever that spikes every 48 hours (fever on the 1st day → ski…
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{{c1::Malaria}} is a potentially life-threatening infectious disease caused by Plasmodium parasites.
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Malaria is transmitted to humans from the vector: the {{c1::female Anopheles mosquito}}.
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Malaria has an incubation period of {{c1::7-30}} days
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Malaria manifests with non-specific symptoms like {{c1::fever}}, {{c1::nausea}}, and {{c1::vomiting}}.
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Describe the mosquito life cycle and mosquito breeding sites.
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Describe the life cycle of Plasmodium spp. in the mosquito and human carrying malaria.
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The gold standard test for detecting and identifying malaria = {{c1::stained blood smears}} → using thick + thin blood smears AND {{c2:…
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Thick versus thin blood smear
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Describe the developmental stages of plasmodium in red blood cells.
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Malaria relapse is an emergence of {{c1::new}} parasitemia from {{c1::hypnozoites}} that have been {{c1::dormant}} in th…
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Malaria recrudescence is a {{c1::recurrence}} of malaria illness caused by {{c1::persistence of blood forms in small numbers between at…
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The majority of malaria cases are in {{c1:location:Sub Saharan Africa}} in children under the age of {{c1::5}}.
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