Notes in Hruban Ch 1 - 18

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Published	09/27/2024	What are the 3 fundamental issues?
Published	09/27/2024	What are the 5 basic steps of grossing?
Published	09/27/2024	What is the pro of fixation before dissection? Cons?
Published	09/27/2024	What are the 3 goals of grossing?
Published	09/27/2024	Attempts to maximize info that can be obtained from a given diagnosis
Published	09/27/2024	In general, most sections of a tumor should be obtained from _____________
Published	09/27/2024	When sampling a margin, which cut is usually preferred?
Published	09/27/2024	What is the advantage of a perpendicular section?
Published	09/27/2024	What is a pro of a shave section?
Published	09/27/2024	LNs larger than ____mm should be serially sectioned in 2 - 3 intervals
Published	09/27/2024	A comprehensive statement that integrates macroscopic and microscopic findings
Published	09/27/2024	What is central to histologic preparation?
Published	09/27/2024	What are the 4 groups of fixatives based on the MOA?
Published	09/27/2024	Fixative agent like formaldehyde that acts by cross-linking proteins
Published	09/27/2024	Fixative agent like osmium tetroxide and potassium permanganate; possibly cross-link
Published	09/27/2024	Fixative that are all denaturing agents
Published	09/27/2024	Fixative agents that act by forming insoluble metallic precipitates
Published	09/27/2024	Formalin tends to remove glycogen and is therefore not suitable for ___________
Published	09/27/2024	What is the fixation rate of 10% NBF?
Published	09/27/2024	Which fixative is one of the slowest for which tissues should be cut into 1mm cubes and immediately placed in the refrigerated fixative?
Published	09/27/2024	This fixative is rarely used do to its disadvantages of: slow penetration causing excessive hardening, shrinkage and cell distortion, dissolves fats
Published	09/27/2024	Fixative of choice for testicular bx?
Published	09/27/2024	Tissue w/ hollow lumina should be opened and solid tissue partially sectioned at ________mm intervals
Published	09/27/2024	Tissue submitted for processing should NOT be greater than ___mm
Published	09/27/2024	Tissue w/ adipose tissue should NOT be greater than ___mm
Published	09/27/2024	How much space should be b/w the tissue and all cassette edges?
Published	09/27/2024	Employ an unlabeled Ab to a specific tissue Ag followed by treatment in 1+ steps w/ an enzyme-labeled Ab
Published	09/27/2024	What are 3 things that can improve IHC results?
Published	09/27/2024	In IHC, what does overfixation cause?
Published	09/27/2024	Acid decal must be removed so it does NOT ________________
Published	09/27/2024	What are the 3 methods for intraoperative consult?
Published	09/27/2024	What fixative is preferred for molecular genetic analytics?
Published	09/27/2024	What is the focus for molecular genetic analysis?
Published	09/27/2024	What is the most versatile and easy to use system for photography in the gross room?
Published	09/27/2024	If tumor is visualized grossly, what staining is sufficient for LNs
Published	09/27/2024	What structures are included in the supraglottis?
Published	09/27/2024	What structures are included in the glottis?
Published	09/27/2024	What is the region of the subglottis?
Published	09/27/2024	What are the mucosal landmarks of the larynx?
Published	09/27/2024	Triangular space anterior to the base of the epiglottis
Published	09/27/2024	Ill-defined area composed of loose CT b/w thyroid cartilage and 2 membranes that form the structural base for the vocal cords
Published	09/27/2024	Anterior dense ligamentous attachment of true vocal cords to thyroid cartilage
Published	09/27/2024	Which direction does the epiglottis close?
Published	09/27/2024	What is inked in a larynx specimen?
Published	09/27/2024	What MARGINS are sampled and how in a larynx specimen (3)?
Published	09/27/2024	Voice preserving procedure in which only half of the larynx (thyroid cartilage, true & false vocal cords, ventricle) is removed
Published	09/27/2024	Procedure performed for tumors of the supraglottic larynx - supraglottis removed w/ horizontal incision through ventricles
Published	09/27/2024	What is unique of the parotid glands?
Published	09/27/2024	Orientation and spread of the maxilla:Inferior
Published	09/27/2024	Orientation and spread of the maxilla:Superior
Published	09/27/2024	Orientation and spread of the maxilla:Medial
Published	09/27/2024	Orientation and spread of the maxilla:Anterior/lateral
Published	09/27/2024	Orientation and spread of the maxilla:Posterior
Published	09/27/2024	What are the margins in a maxillectomy?
Published	09/27/2024	Does the esophagus have a serosa?
Published	09/27/2024	Esophageal tumors:At GEJ, classified as ______________ if epicenter is in esophagus
Published	09/27/2024	Esophageal tumors:If epicenter is in stomach, classified as _______________
Published	09/27/2024	Esophageal tumors:If epicenter is at junction of tube esophagus and sac stomach, classified as ________
Published	09/27/2024	What are the 2 margins of an esophageal specimen?
Published	09/27/2024	What are the TOTAL sections submitted in an esophageal specimen?
Published	09/27/2024	What are the 4 anatomical regions of the stomach?
Published	09/27/2024	Which region of the stomach displays prominent rugal folds?
Published	09/27/2024	Which region of the stomach has comparatively flat mucosa?
Published	09/27/2024	Does the stomach have an adventitia or serosa?
Published	09/27/2024	In a gastrectomy, what should be measured fresh?
Published	09/27/2024	In a gastrectomy, if the tumor involves ___% of the esophagus, it's classified esophageal
Published	09/27/2024	For a gastrectomy, what are the additional sections submitted for tumor?
Published	09/27/2024	For a gastrectomy, what are the additional sections submitted for peptic ulcer dx?
Published	09/27/2024	For a gastrectomy, what are the standard sections?
Published	09/27/2024	For non-neoplastic intestinal dx, how should the specimen be placed in the cassette?
Published	09/27/2024	For a resection for inflam bowel dx, how should the sm int be opened?
Published	09/27/2024	For a resection for inflam bowel dx, how should the lg int be opened?
Published	09/27/2024	What are the standard sections for non-neoplastic intestinal dx?
Published	09/27/2024	What is the major objective in dissecting a simple appendectomy?
Published	09/27/2024	The inflammatory process in an appendix converts the glistening, smooth, than serosa into a surface that is ____, __________ and ________________
Published	09/27/2024	If storage dx is suspected in a liver bx, what fixative should a sm portion be placed in and for what test?
Published	09/27/2024	For a partial hepatectomy, what serves as the surgical resection margin?
Published	09/27/2024	How is the liver sectioned, according to resection margin?
Published	09/27/2024	What is the aim of liver transplants?
Published	09/27/2024	What is the orientation the porta hepatis (bile duct, artery, vein)?
Published	09/27/2024	Where does the dissection begin on a liver?
Published	09/27/2024	What sections in a liver resection are taken as a shave?
Published	09/27/2024	After taking the vessels, in a liver resection, what is located, probed and searched for?
Published	09/27/2024	What is included in the perpendicular section at the hilum of a liver resection?
Published	09/27/2024	How many sections are taken from the lobes of the liver?
Published	09/27/2024	_______________ forms a conduit where bile produced by hepatocytes is transmitted and concentrated in the _____________ and excreted into the ________…
Published	09/27/2024	Bile secreted into _________ drain into the _________________ bile ducts which join to form larger __________ unto L & R _________ emerging from the l…
Published	09/27/2024	L & R hepatic ducts join to form the _________, then joined by the ___________ of the gallbladder to form the __________________________
Published	09/27/2024	The distal ___________ joins w/ the __________________ w/in the head of the pancreas and empties into the duodenum via the ________________
Published	09/27/2024	What is the smooth side of the gallbladder lined by?
Published	09/27/2024	What is the surgical margin of the gallbladder?
Published	09/27/2024	Do NOT open gallbladder along ________; could dislodge stones
Published	09/27/2024	If a neoplasm is present in the gallbladder (exophytic lsn) what should be inked? Why?
Published	09/27/2024	What are most commonly encountered as a part of pancreaticoduodenectomy, partial or total hepatectomies?
Published	09/27/2024	What is inked in a local or segmental biliary resection?
Published	09/27/2024	Carcinoma of bile ducts can infiltrate diffusely into the bile duct wall and mimic a ____________________________
Published	09/27/2024	Where are choledochal cysts inked?
Published	09/27/2024	How are choledochal cysts opened?
Published	09/27/2024	____% of choledochal cysts in adults harbor carcinoma; the risk of carcinoma developing in adults ____________ w/ age
Published	09/27/2024	What are the sections taken for a choledochal cyst?
Published	09/27/2024	Procedure for whipple specimen
Published	09/27/2024	What are the 4 structural components in a whipple?
Published	09/27/2024	What is the orientation of the duodenum in a whipple?
Published	09/27/2024	Pancreatic groove enveloping superior mesenteric artery and vein
Published	09/27/2024	What is inked in a whipple?
Published	09/27/2024	In a whipple, how is the duodenum opened?
Published	09/27/2024	What are the shave sections in a whipple?
Published	09/27/2024	What are the perpendicular sections in a whipple?
Published	09/27/2024	If the gallbladder is present in a whipple specimen, how is it opened?
Published	09/27/2024	What is inked in a distal pancreatectomy?
Published	09/27/2024	If a cystic tumor is present in a pancreatectomy, when would it be entirely submitted?
Published	09/27/2024	Do mucinous cystic neoplasms or intraductal papillary mucinous neoplasms involve the duct system?
Published	09/27/2024	Formed by the confluence of pancreatic and distal CBDs as they pass through the wall of the duodenum
Published	09/27/2024	What structures are submitted in an ampullectomy?
Published	09/27/2024	What is inked in an ampullectomy?
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