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Notes in
Chapter_03:_Blood_products
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carolina-beer-green-mirror-angel-island
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Published
07/07/2024
All blood products carry some risk of HIV and hepatitis transmission except {{c2::albumin}} and {{c1::serum globulins}}
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07/07/2024
{{c2::Low-birth weight}} infants, {{c3::bone marrow}} transplant, and {{c3::solid organ}} transplant patients should recieve {{c1::CMV}} neg…
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Females of childbearing age should receive {{c1::Rh-negative}} blood
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Stored blood has a {{c1::high}}er affinity for oxygen due to {{c2::de}}creased concentration of {{c3::2,3-BPG}}
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Type and {{c1::screen}} determines the blood type
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Type and {{c1::cross}} determines whether the patient's blood reacts with a sample taken from the physical bag in blood bank
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On average, one six-pack of platelets increases the platelet count by {{c1::50,000}}
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On average, one unit of packed RBCs should increase the H{{c2::gb}} by {{c1::1}} and the H{{c2::ct}} by {{c1::3-5}}
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Acute hemolysis will present with a {{c3::hapto}}globin level < {{c2::50}}, {{c3::free hemo}}globin level > {{c2::5}}, and increased {{c1::…
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ABO incompatability acute hemolysis is treated with {{c4::fluids}}, {{c3::diuretics}}, {{c2::bicarb}}, and {{c1::pressors}}
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Anesthetized patients with ABO incompatibility hemolysis present with {{c1::diffuse bleeding}}
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Delayed hemolysis from transfusions presents with {{c2::mild jaundice}} and is treated with {{c1::observation}}
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Blood products that are NOT immunoreactive can still cause hemolysis if they are {{c1::squeezed rapidly}}
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The most common type of transfusion reaction is {{c1::febrile non-hemolytic}}
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{{c3::Febrile non-hemolytic transfusion}} reaction is caused by {{c2::recipient::recipient or donor}} {{c1::antibody}} reacting against the …
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The treatment for febrile non-hemolytic transfusion reaction is {{c1::discontinue the transfusion}}, rule out {{c2::acute hemolytic reaction}}, a…
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In febrile non-hemolytic transfusion reaction, bothersome or high fever is treated with {{c1::tylenol}}
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Severe {{c2::chills/rigors}} in a febrile non-hemolytic transfusion reaction are treated with {{c1::meperidine}}
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{{c3::Urticaria}} after blood transfusion is usually caused by reaction of {{c2::recipient::donor or recipient}} {{c1::antibodies}} to the {{c2::…
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07/07/2024
A genetic cause of urticaria after blood transfusion is {{c1::IgA deficiency}}
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07/07/2024
Blood transfusion urticaria is treated with {{c1::diphenhydramine}}
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Blood transfusion {{c3::anaphylaxis}} is usually caused by {{c2::donor::recipient or donor}} {{c1::IgA}} reacting with {{c2::recipient::recipient…
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07/07/2024
Transfusion anaphylaxis is treated with {{c1::epinephrine}}, {{c2::fluids}}, {{c3::pressors}}, steroids, and antihistamines
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07/07/2024
{{c1::TRALI}} is caused by {{c3::donor::recipient or donor}} {{c2::antibodies}} reacting to {{c3::recipient::recipient or donor}} {{c2::WBCs}},&n…
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{{c1::Both TACO and TRALI::TACO or TRALI}} occurs {{c3::less}} than {{c2::6}} hours after transfusion
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The risk of {{c1::TACO::TRALI or TACO}} correlates to the number of units transfused
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TACO is caused by {{c1::volume overload of the circulatory system}}
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TACO is diagnosed with at least {{c7::3}} of the following after a transfusion: - {{c1::Acute respiratory distress::symptom}} - {{c2::CXR wi…
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Multiple transfusions can cause hyp{{c1::o}}{{c2::calc}}emia because it gets bound by the {{c3::sodium citrate}} in the donor blood
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Massive transfusion can cause a dilutional {{c2::anemia}} and {{c1::thrombocytopenia}}
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Massive transfusion {{c1::de}}creases blood coagulability
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07/07/2024
The most common bacterial contaminant in blood products is {{c1::gram negative rods (usually E. coli)}}
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07/07/2024
The most commonly contaminated blood product is {{c1::platelets}} because {{c2::they are not refrigerated}}
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07/07/2024
{{c1::Chagas disease::parasite}} can be transmitted via blood transfusions
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