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Published	01/11/2024	2e4e7036ec3846ec9bece4f7f4d2dae1-oa-1
Published	01/09/2024	2e4e7036ec3846ec9bece4f7f4d2dae1-oa-2
Published	01/09/2024	2e4e7036ec3846ec9bece4f7f4d2dae1-oa-3
Published	01/09/2024	2e4e7036ec3846ec9bece4f7f4d2dae1-oa-4
Published	01/09/2024	{{c4::Cellulitis}}:Affects deep {{c1::dermis}} and {{c1::subcutaneous}} tissueSpreading inflammation pits80% caused by gram {{c2::positive}} organisms…
Published	01/09/2024	ac6f7173605240dca1c04b5a94d9aef4-oa-1
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Published	01/09/2024	ac6f7173605240dca1c04b5a94d9aef4-oa-4
Published	01/09/2024	Warts are primarily caused by {{c1::HPV (dsDNA virus)::pathogen}}
Published	01/11/2024	{{c1::Molluscum contagiosum}}:{{c2::Benign}} viral infection of skinSmooth surface with {{c4::umbilicated}} firm papulesMainly caused by {{c3::poxviru…
Published	01/09/2024	{{c4::Molluscum contagiosum}}:Spread via {{c1::skin-skin}} contact, {{c2::fomite}} exposure, and auto{{c3::inoculation}}
Published	01/09/2024	{{c1::HSV-1}}: cause of most cases of {{c2::orolabial}} herpes
Published	01/09/2024	{{c1::HSV-2}}: cause of most cases of {{c2::genital}} herpes
Published	01/09/2024	HSV:{{c1::Grouped}} vesicles on erythematous basePainful
Published	01/09/2024	Orolabial HSV triggers: {{c1::UV}} exposure, {{c2::surgical/dental}} procedures, URI
Published	01/09/2024	Example of {{c1::herpetic whitlow}}
Published	01/09/2024	Example of {{c1::Eczema Herpeticum}}
Published	01/09/2024	{{c1::Varicella-Zoster Virus (VZV)}}: causes {{c2::varicella (chickenpox)}} and {{c3::herpes zoster (shingles)}}Transmitted via {{c4::airbone droplets…
Published	01/09/2024	{{c2::Varicella}}:Mild fever, malaise, myalgiaPapules start on {{c1::scalp/face}} and spreadEvolves into vesicles with red halos (like a {{c3::dew dro…
Published	01/09/2024	{{c3::Herpes Zoster}}: also called {{c2::shingles}}{{c4::Grouped}} vesicles on erythematous baseDermatomal distribution that is {{c1::uni}}lateral
Published	01/09/2024	{{c1::Hutchinson's}} sign of Herpes Zoster: vesicles on {{c2::side/tip of nose}}Risk of ocular involvment when involving the {{c3::V1}} nerve
Published	01/09/2024	{{c1::Ramsay Hunt}} syndrome of Herpes Zoster: {{c2::geniculate ganglion}} of facial nerve{{c3::Ear}} pain, loss of tasteRisk of facial nerve {{c4::pa…
Published	01/09/2024	b27632cb65a74625a1503a9209538828-ao-1
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Published	01/09/2024	b27632cb65a74625a1503a9209538828-ao-3
Published	01/09/2024	b27632cb65a74625a1503a9209538828-ao-4
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Published	01/09/2024	b27632cb65a74625a1503a9209538828-ao-6
Published	01/11/2024	{{c2::Tinea capitis}}:Common in {{c1::school-aged children::demographic}}Spread via {{c3::direct contact}}Can cause symptoms like seborrhea, psoriasis…
Published	01/09/2024	{{c1::Tinea pedis}}: also known as {{c2::Athlete's foot}}Mainly occurs in {{c3::adults::demographics}}Shoes aid in colonization
Published	01/09/2024	Example of {{c1::Tinea Manum}}
Published	01/09/2024	{{c1::Tinea Unguium}}: also called {{c2::onychomycosis}}{{c3::Nail}} dystrophy that creates a reservoir of fungi
Published	01/09/2024	{{c1::KOH}} test: easiest/cheapest method to diagnose {{c2::fungal}} infection
Published	01/09/2024	Tinea {{c3::capitis}} and tinea {{c3::unguium}} requires {{c1::oral antifungals}}. Other types of dermatophytosis can use {{c2::topical creams}}
Published	01/09/2024	Example of {{c1::Tinea Versicolor}}
Published	01/09/2024	{{c1::Tinea Versicolor}}:Caused by {{c2::Malassezia}}, a lipophilic yeastFavors the back and chestTends to recur in {{c3::summer}} (due to sweat)Treat…
Published	01/09/2024	{{c3::Candida}}:Multiplies in {{c2::warm}} and {{c2::moist}} areasCauses bright red, {{c1::satellite}} pustulesCan identify using {{c4::KOH}} test
Published	01/09/2024	Treatment of candidiasis: {{c1::imidazoles}} and/or {{c2::topical steroids}}
Published	01/09/2024	{{c3::Scabies}}:Caused by ectoparasitic {{c6::mite}}Most common in {{c1::immunocompromised}} individuals or those in {{c2::congregated}} facilitiesPap…
Published	01/09/2024	Treatment for scabies:Topically can use 5% {{c1::permethrin}} creamOrally can use oral {{c2::ivermectin}}
Published	01/09/2024	{{c2::Benzyl alcohol}} lotion and dimethicone are common treatments for {{c1::lice}}
Published	01/09/2024	{{c1::Atopic dermatitis}}: also known as {{c2::Eczema}}Erythematous {{c4::scaly}} patchesCharacteristic distribution{{c3::Itching::Key sign}}
Published	01/09/2024	{{c2::Filaggrin}}: important protein required for {{c1::terminal keratinocyte}} differentiation
Published	01/09/2024	Loss of function Filaggrin mutation decreases natural moisturizing factor and increases risk of {{c1::atopic dermatitis (Eczema)}}
Published	01/09/2024	Immunology of atopic dermatitis:Acute: increased {{c1::Th2}} pro-inflammtory cytokinesChronic: shift to {{c2::Th1}} cytokine phenotype
Published	01/09/2024	First line treatment of atopic dermatitis: topical {{c1::corticosteroids}}
Published	01/09/2024	ff6c11ea187740ee9a4cbc65afe6639d-ao-1
Published	01/09/2024	ff6c11ea187740ee9a4cbc65afe6639d-ao-2
Published	01/09/2024	{{c1::Seborrheic Dermatitis}} pathophys:Proliferation of {{c2::stratum corneum}} resulting in thick scales/hyperkeratosisOveractive {{c3::oil gland}} …
Published	01/09/2024	First line treatment for Seborrheic Dermatitis: {{c1::oils}} with gentle brushing
Published	01/09/2024	Example of {{c1::Vitiligo}}
Published	01/09/2024	Example of {{c1::nevus depigmentosus}}
Published	01/09/2024	Vitiligo is reproducibly noted to occur in zones of frequent skin friction/trauma: {{c1::Koebner's}} phenomenon
Published	01/09/2024	Examples of {{c1::poliosis}}
Published	01/09/2024	{{c1::Oculocutaneous albinism}}: diffuse reduction of pigment in hair, skin, and eyes
Published	01/09/2024	9a3dfc994c7c418e8e2227ec46d4a525-oa-1
Published	01/09/2024	9a3dfc994c7c418e8e2227ec46d4a525-oa-2
Published	01/09/2024	9a3dfc994c7c418e8e2227ec46d4a525-oa-3
Published	01/09/2024	9a3dfc994c7c418e8e2227ec46d4a525-oa-4
Published	01/09/2024	Infantile hemangioma treatment: {{c1::Hemangeol (propanolol)}}
Published	01/09/2024	{{c1::Pyogenic granuloma}}: red, rapidly growing papule/nodule
Published	01/09/2024	Pyogenic granuloma treatment: {{c1::shave excision}}, pulsed dye {{c2::laser}}
Published	01/09/2024	Vascular malformations:Partially {{c2::blanching}} red patches{{c1::Clear-to-purple}} vesicles
Published	01/11/2024	{{c2::Impetigo}}:Most common in {{c1::children::demographic}}{{c3::Warm, humid}} weather predisposes{{c4::Golden-yellow::color}} crustsMainly caused b…
Published	01/11/2024	Impetigo treatment: {{c1::topical/systemic antibiotics}}
Published	01/11/2024	Bacterial Folliculitis:Infection of {{c1::hair follicle}}Commonly caused by {{c2::Staph aureus::pathogen}}
Published	01/11/2024	If initial antibiotics don't work with bacterial folliculitis, you should consider {{c1::gram-negative}} folliculitis
Published	01/11/2024	Pseudomonal folliculitis is mainly due to exposure to {{c1::improperly chlorinated hot tubs/pools}}
Published	01/11/2024	Abscess vs Furuncle vs Carbuncle:Abscess: happens in any cutaneous siteFuruncle: abscess of {{c1::hair follicle}} and surrounding tissueCarbuncle: col…
Published	01/11/2024	How to treat abscess, furuncles, and carbuncles:Main treatment is {{c1::incision}} and {{c1::drainage}}Systemic antibiotics can be used
Published	01/11/2024	{{c2::Erythrasma}}:Superficial infection within {{c3::stratum corneum}}Initially {{c4::red}} patches that fade to {{c4::brown}} over timeSharply delin…
Published	01/11/2024	Erythrasma treatment: topical {{c1::aluminum chloride}}, {{c2::-mycins (macrolides)::antibiotics}}
Published	01/11/2024	Main treatments of HSV/VZV:Antivirals (ends in -{{c1::clovir}})If resistant, treat with {{c2::Foscarnet}}
Published	01/11/2024	Example of {{c1::Tinea Corporis}}
Published	01/11/2024	Example of {{c1::Tinea Cruris}}
Published	01/11/2024	{{c3::Azoles}}: inhibits {{c1::ergosterol}} synthesis via targeting {{c2::lanosteral demethylase::enzyme}}
Published	01/11/2024	{{c3::Allylamines}}: inhibits {{c1::ergosterol}} synthesis via targeting {{c2::squalene epoxidase::enzyme}}
Published	01/11/2024	{{c2::Candins}} inhibit synthesis of {{c3::B-1,3-glucan}}, an important part of the fungal {{c1::cell wall}}
Published	01/11/2024	Most common presentation of psoriasis is {{c1::sharply demarcated}} erythematous scaly plaques
Published	01/11/2024	Psoriasis histology:Epidermis is {{c1::acanthotic (thickened)}}Focal {{c2::neutrophils}} and lymphocytesFoci of parakeratosis in epidermis with absenc…
Published	01/11/2024	Examples of {{c1::Psoriasis}}
Published	01/11/2024	General treatments for psoriasis include topical treatments like {{c1::corticosteroids}}, as well as {{c2::phototherapy}}
Published	01/11/2024	Systemic treatments for psoriasis include the chemotherapeutic drug {{c1::methotrexate}} or the retinoid {{c2::acitretin}}
Published	01/11/2024	Lichen Planus:Causes flat-topped papules/plaques on the skin with network of fine white lines on surface ({{c1::Wickham}} striae)
Published	01/11/2024	Examples of {{c1::Lichen planus}}
Published	01/11/2024	{{c2::Pityriasis Rosea}} progression:Starts with {{c3::Herald}} patch (solitary patch that appears first)Followed by round papules/plaques on trunk/ex…
Published	01/11/2024	Allergic contact dermatitis:{{c1::Localized}} to site of contactRepeat exposure to {{c2::previously sensitized}} individual
Published	01/11/2024	{{c1::Patch testing}} is the gold standard for diagnosing allergic contact dermatitis
Published	01/30/2024	{{c3::Stasis dermatitis::Skin condition}} is commonly seen with {{c1::chronic venous}} insufficiency such as in {{c2::venous hypertension}}
Published	01/11/2024	Key management of stasis dermatitis is {{c1::compression}} therapy
Published	01/11/2024	{{c1::Erythema Multiforme}} is an abrupt onset of {{c2::papular target}} lesions mainly occuring on {{c3::hands}} and {{c3::face}}. It is commonly pre…
Published	01/11/2024	{{c1::Acanthosis Nigricans}} is a velvety hyperpigmentation that mainly occurs on the {{c2::neck}} and {{c2::axilla}}. It is associated with {{c3::ins…
Published	01/11/2024	Example of {{c1::Keloid}}
Published	01/11/2024	{{c3::Keloid}}:Exuberant scar tissue with excessive proliferation of {{c1::collagen}}Treat cautiously because it has a high {{c2::recurrence rate}}
Published	01/11/2024	Cherry hemangioma:Common acquired {{c1::blood vessel}} lesionTreatment: {{c2::not really needed}}
Published	01/11/2024	{{c5::Xanthoma}}:Focal collection of lipid-laden {{c3::histiocytes}} in dermis{{c1::Yellow}} papules, plaques and nodules (due to presence of {{c2::fa…
Published	01/11/2024	Examples of {{c1::xanthoma}}
Published	01/11/2024	{{c4::Glomous tumor}}:Usually {{c1::painful}}, especially in response to temp/pressure{{c2::Blue-red}} colorUsually occurs in the {{c3::nailbed/palm}}
Published	01/11/2024	Example of {{c1::glomus tumor}}
Published	01/11/2024	{{c2::Lipoma}}:Soft, round, movable, non-tender subcutaneous nodule of fatBiopsy only if it {{c1::grows rapidly}}
Published	01/11/2024	{{c5::Epidermal inclusion cyst}}:Subcutaneous, skin colored nodule with central {{c1::punctum}}Sac of hair follicle epithelium filled with {{c2::lipid…
Published	01/11/2024	Examples of {{c1::lipoma}}
Published	01/11/2024	Examples of {{c1::epidermal inclusion cysts}}
Published	01/11/2024	{{c1::Acitinic Keratosis}}:{{c2::Precancerous}} epidermal neoplasm caused primarily by {{c3::UV light}}Treat with {{c4::cryotherapy}} or topical medic…
Published	01/11/2024	Example of {{c1::acitinic keratosis}}
Published	01/11/2024	5-fluorouracil: {{c1::pyrimidine}} analogue that binds and inhibits {{c2::thymidylate synthetase}}
Published	01/11/2024	Skin cancer's main cause is {{c1::UV radiation}}
Published	01/11/2024	{{c1::Basal cell carcinoma}}:Malignancy of epidermal basal cell {{c2::keratinocytes}}Mostly caused by {{c3::UV radiation}}
Published	01/11/2024	Most common skin cancer: {{c1::basal cell carcinoma}}
Published	01/11/2024	Examples of {{c1::superficial BCC}}
Published	01/11/2024	{{c3::Nodular}} BCC:Pearly/semitransluscent papule/noduleOften has central {{c2::depression}} and {{c1::telangiectasias (small visible blood vessels)}…
Published	01/11/2024	Examples of {{c1::nodular BCC}}
Published	01/11/2024	BCC histology:Basaloid cells budding off epidermis or in clusters in dermisPeripheral {{c1::palisading}}Stromal {{c2::retraction}} ({{c2::clefting}})
Published	01/11/2024	Examples of {{c1::basal cell carcinoma}}
Published	01/11/2024	{{c2::Squamous cell carcinoma}}:Malignancy of {{c1::keratinocytes}} in the process of differentiating into stratum corneumCaused by UV, X-rays, carcin…
Published	01/11/2024	Squamous cell carcinoma:{{c1::Ulcerative}} or {{c1::hyperkeratotic}} papules/nodules
Published	01/11/2024	Examples of {{c1::squamous cell carcinoma}}
Published	01/11/2024	{{c4::Keratoacanthoma}}: variant of SCCAppears very {{c2::rapidly}}, but can spontaneously {{c1::regress}}{{c3::Crateriform}} nodule with keratin core
Published	01/11/2024	Examples of {{c1::keratoacanthoma}}
Published	01/11/2024	SCC histology:Invasion of {{c2::dermis}} by atypical keratinocytesKeratin {{c1::pearls}}, squamous {{c1::eddies}}
Published	01/11/2024	Examples of {{c1::squamous cell carcinoma}}
Published	01/11/2024	BCC and SCC treatment:{{c1::Excision}} is preferredIf smaller, can consider {{c2::destruction (radiation)}}
Published	01/11/2024	{{c1::Mohs micrographic}} surgery is useful for lesions in {{c2::sensitive}} areas or for {{c2::big, aggressive}} tumors
Published	01/11/2024	Non-surgical options for BCC and SCC:BCC: {{c1::hedgehog}} inhibitors (vismodegib)SCC: {{c2::PD1}} inhibitors (cemiplimab) or {{c2::EGFR}} inhibitors …
Published	01/11/2024	{{c1::BRAF kinase}} mutations is a risk factor for {{c2::melanoma}}
Published	01/11/2024	Examples of {{c1::melanoma}}
Published	01/11/2024	Melanoma histology:Aggregates of atypical {{c1::melanocytes}}Usually stains positive for {{c2::S-100}} tumor marker
Published	01/11/2024	Example of {{c1::melanoma}}
Published	01/11/2024	Melanoma treatment:Main treatment is {{c2::surgical excision}}Immunotherapy: {{c1::PD1}} inhibitors (nivolumab) or {{c1::BRAF}} inhibitors (vemurafeni…
Published	01/11/2024	{{c3::Angiosarcoma}}:Rare {{c2::blood vessel}} malignancyAssociated with radiation or chronic {{c1::lymphedema}}Often appears as benign {{c4::bruise-l…
Published	01/11/2024	Examples of {{c1::angiosarcoma}}
Published	01/11/2024	{{c3::Kaposi's sarcoma}}:Malignant vascular tumor caused by {{c2::HHV8::pathogen}}{{c1::Purple::Color}} papules, plaques, macules, and nodules
Published	01/11/2024	Examples of {{c1::Kaposi's sarcoma}}
Published	01/11/2024	{{c1::Cutaneous T-cell}} lymphoma: also called mycosis fungoidesSlow, progressive proliferation of malignant epidermotrophic T-cellsGoes from {{c2::pa…
Published	01/11/2024	Examples of {{c1::cutaneous T-cell lymphoma}}
Published	01/11/2024	Example of {{c1::cutaneous T-cell lymphoma}}
Published	01/11/2024	{{c3::Merkel cell carcinoma}}:Caused by early {{c1::B cell}} lineageAsymptomatic, rapidly growing {{c2::nodule}} on head/neck
Published	01/11/2024	Examples of {{c1::Merkel cell carcinoma}}
Published	01/11/2024	{{c3::Seborrheic Keratosis}}:{{c2::Benign}} neoplasm of epidermal cellsMay be confused for {{c1::melanoma}}
Published	01/11/2024	{{c3::Seborrheic Keratosis}}:{{c1::Waxy}}, {{c2::"stuck-on"}} appearance with a verrucous, crumbly surface
Published	01/11/2024	Examples of {{c1::seborrheic keratosis}}
Published	01/11/2024	{{c2::Solar lentigo}}:Localized {{c3::melanocyte}} proliferation with brown, irregular maculesPrimarily occurs in {{c1::older individuals::demographic…
Published	01/11/2024	Solar lentigo treatment: {{c1::bleaching}} creams, lasers
Published	01/11/2024	Examples of {{c1::solar lentigo}}
Published	01/11/2024	8cdccf329b774294ac35bd73ce58ead6-ao-1
Published	01/11/2024	8cdccf329b774294ac35bd73ce58ead6-ao-2
Published	01/11/2024	{{c1::Dysplastic}} nevi:Irregular {{c2::pigmentation}} and {{c2::borders}}
Published	01/11/2024	50% of melanomas are associated with a {{c1::melanocytic nevus}}. Be suspicious of an "{{c2::ugly duckling}}" mole
Published	01/11/2024	{{c3::Dermatofibroma}}: dermal {{c4::fibrotic}} papule or small noduleCommonly seen in {{c1::young adults::demographic}} primarily in the {{c2::thighs…
Published	01/11/2024	Dermatofibroma: pinching results in central {{c1::dimpling}} ({{c1::dimpling}} sign)
Published	01/11/2024	Examples of {{c1::dermatofibroma}}
Published	01/30/2024	{{c1::Basal cell}} carcinomas are shiny while {{c1::squamous cell}} carcinomas are scaly
Published	01/11/2024	Examples of {{c1::pigmented BCC}}
Published	01/11/2024	Examples of {{c1::morpheaform/sclerosing BCC}}
Published	01/11/2024	Examples of {{c1::sqamous cell carcinoma in situ (Bowen's disease)}}
Published	01/30/2024	Acne is a disorder of {{c1::pilosebaceous}} unit
Published	01/30/2024	Acne is associated with {{c1::sebum}} production
Published	01/30/2024	Acne occurs due to formation of a {{c1::comedo}} from accumulation of {{c4::corneocytes}}. A bottleneck is formed due to a {{c2::hyperkeratotic}} plug…
Published	01/30/2024	Non-inflammatory acne: open and closed {{c1::comedones}}Inflammatory acne: {{c2::papules}}, {{c2::pustules}}, {{c2::nodules}}, {{c2::cysts}}Can eventu…
Published	01/30/2024	{{c1::Acne fulminans}}: most severe form of acne with significant scarring
Published	01/30/2024	Examples of {{c1::acne}}
Published	01/30/2024	{{c3::Acne}} treatments:{{c1::Retinoids}} (both topical and oral){{c2::Antibiotics}} (both topical and oral)
Published	01/30/2024	Rosacea:More common in {{c2::lighter}} skin tones{{c1::Middle age::Age}} onset
Published	01/30/2024	Rosacea symptoms:Facial {{c1::erythema}}{{c2::Papules}} and {{c2::pustules}}, but not comedones{{c3::Phymatous}} changes: sebaceous gland {{c4::hypert…
Published	01/30/2024	Examples of {{c1::rosacea}}
Published	01/30/2024	Rosacea treatment:Facial {{c4::skin care}}, sunscreen, moisturizerTopical {{c1::antibiotics}}, {{c2::ivermectin}}, and {{c3::selective a-adrenergic ag…
Published	01/30/2024	{{c4::Pilonidal cyst}}:Mainly occurs in upper gluteal cleft or {{c1::sacrococcygeal}} areaInflamed cystic swellingOccurs primary in {{c2::hairy males}…
Published	01/30/2024	Pilonidal cyst treatment: {{c1::surgery}}
Published	01/30/2024	Example of {{c1::pilonidal cyst}}
Published	01/30/2024	Erythema nodosum: most common form of {{c1::panniculitis}} (inflammation of {{c2::subcutaneous fat}})
Published	01/30/2024	{{c3::Erythema nodosum}} causes:{{c2::Streptococcal}} is most common infectionDrugs: {{c1::oral contraceptives}}, sulfonamides, penicillinSarcoidosis,…
Published	01/30/2024	Examples of {{c1::erythema nodosum}}
Published	01/30/2024	Pemphigus:Autoimmune {{c1::blistering}} disease{{c3::Intraepi}}dermal blisters (makes them {{c2::fragile}}){{c4::IgG}} autoantibodies against cell suf…
Published	01/30/2024	Example of {{c1::pemphigus}}
Published	01/30/2024	Pemphigus {{c2::vulgaris}} has {{c1::mucosal}} involvement and is more {{c3::severe}}, while pemphigus {{c2::foliaceus}} has {{c1::no mucosal}} involv…
Published	01/30/2024	Paraneoplastic pemphigus is associated with an underlying {{c1::neoplasm}}
Published	01/30/2024	Examples of {{c1::pemphigus vulgaris}}
Published	01/30/2024	Examples of {{c1::pemphigus foliaceus}}
Published	01/30/2024	{{c3::Pemphigus}} treatment:Systemic {{c2::corticosteroids}}Main corticosteroid-sparing agent: {{c1::rituximab}}
Published	01/30/2024	{{c2::Bullous pemphigoid}}: Autoimmune {{c1::subepi}}dermal blistering diseaseOnset occurs {{c3::after 60::age}}Autoantibodies against {{c4::hemidesmo…
Published	01/30/2024	Examples of {{c1::bullous pemphigoid}}
Published	01/30/2024	Examples of {{c1::bullous pemphigoid}}
Published	01/30/2024	Bullous pemphigoid causes:{{c1::Neurological}} disordersSystemic medications (classic example is {{c2::furosemide}})
Published	01/30/2024	Bullous pemphigoid treatment:Topical {{c1::corticosteroids}} for milder disease{{c2::Rituximab}} for extensive disease
Published	01/30/2024	{{c6::Dermatitis herpetiformis}}:Caused by {{c1::gluten}} sensitivity{{c2::Vesicles}} and {{c2::papules}} that are {{c3::pruritic}}{{c4::Subepi}}derma…
Published	01/30/2024	Example of {{c1::dermatitis herpetiformis}}
Published	01/30/2024	Example of {{c1::dermatitis herpetiformis}}
Published	01/30/2024	Dermatitis herpetiformis treatment:{{c2::Gluten}} restrictionCutaneous manifestations can respond to {{c1::dapsone}}
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