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G11 - Integument
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Functions of the skin include:{{c1::Protection}} from mechanical, chemical, and biological insult{{c1::Moisutre}} control{{c1::Thermo}}regulation{{c1:…
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The {{c1::keratinocyte}} is the principal cell of the epidermis. Other relevant cells are {{c1::melanocytes}}, {{c1::langerhans cells (dendritic …
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Thick skin is {{c1::hairless::hairy/hairless}} and contains a stratum {{c1::lucidum}}. It can be found lining the {{c1::sole of the foot or the palm}}…
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Epidermis is adhered to the underlying dermis via a specialized basement membrane and the intercalation of {{c1::epidermal (rete) ridges}} and {{c1::d…
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hypodermis - other name and contents
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Layers of the epidermis (superficial to deep):{{c1::stratum corneumstratum lucidum (only present in thick skin)stratum granulosumstratum spinosumstrat…
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what are keratinocytes
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describe the stratum basale
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The human epidermis renews itself roughly every {{c1::15-30 days}}.
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describe the stratum spinosum
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structure of cytokeratins from smallest to largest
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Keratin aggregates (organized by {{c1::fillagrin}} proteins) are assembled and crosslinked within {{c1::keratohyalin}} granules of the stratum {{c1::g…
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Lamellar granules are {{c1::golgi}}-derived, {{c1::lipid}}-laden granules of the stratum {{c1::granulosum}} of epithelium
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describe the stratum granulosum
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describe the stratum lucidum
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describe the stratum corneum
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Melanocytes originate from the {{c1::neural crest::embrology}}.
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Melanocytes can be found within the {{c1::stratum basale}} of epithelial tissues. They primarily produce {{c1::melanin}} which is stored in {{c1::mela…
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Darker skinned individuals have {{c1::normal}} amounts of melanocyte
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In addition to melanin, {{c1::carotene}} plays a role in developing skin tone. It has a {{c1::yellow}} pigment and can be found in {{c1::skin and adip…
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Langerhans cells can be found intercalated with keratinocytes of the stratum {{c1::spinosum}}
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how do melanosomes orient
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Merkel cells are modified {{c1::keratinocytes}} that detect {{c1::light touch}}. They are located in the stratum {{c1::basale}} are are linked to neig…
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The dermis can be subdivided into the {{c1::papillary}} dermis and the {{c1::reticular}} dermis
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The characteristic wrinkling of aging is primarily caused by the degeneration and underproduction of {{c1::dermal collagen and elastin}}
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Meissner's corpuscles are touch receptors located in the {{c1::papillary}} dermis that detect {{c1::light}} touch and {{c1::low}} frequency vibrations…
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Pacinian corpuscles detect {{c1::deep pressure}} and {{c1::high}} frequency vibrations
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what are ruffini corpuscles
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{{c1::Krause end bulbs}} are mechanoreceptors found in the lining of the oropharynx and eye conjunctiva
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Sebaceous glands secrete {{c1::sebum}} via {{c1::holocrine}} secretion in {{c1::thin}} skin. {{c1::Sebum}} functions as an {{c1::antioxidant}}, {{c1::…
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Sebum functions as an {{c1::antibacterial}}, a {{c1::lubricant}}, and an {{c1::antioxidant}}
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Eccrine sweat glands utilize {{c1::merocrine}} secretion. Apocrine sweat glands utilize {{c1::merocrine}} secretion
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parts of the body that contain sweat glands
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Eccrine sweat glands morphologically form {{c1::simple coiled-tubular glands}} that begin in the {{c1::reticular dermis::tissue layer}} and have ducts…
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Sweat gland secretions can be modulated via {{c1::sympathetic::parasympatethic/sympathetic}} innervations of {{c1::myoepithelial}} cells
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Eccrine sweat glands primarily function in aiding {{c1::thermoregulation}}
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Apocrine sweat glands resemble eccrine sweat glands but have {{c1::dilated lumens}}. They are localized to the {{c1::groin and axilla}} with their sec…
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Hair is found exclusively in {{c1::thin}} skin
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hair growth is strongly influenced by
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where does hair form in the skin?
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what is the terminal dilation of the hair follicle and what is here
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what cells are in direct contact with the dermal papilla of the hair bulb
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what are the layers of hair
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what is the epithelial root sheath
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structure of nails
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The proximal portion of the nail is called the nail {{c1::root}} and is covered by a fold of skin whose stratum corneum extends to form the {{c1::cuti…
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The nail is adhered to the skin by an epidermal plate called the nail {{c1::bed}} which is composed of layers from the strata {{c1::basale and spinosu…
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Nail division occurs within the nail {{c1::matrix}} underlying the {{c1::epo}}nychium
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The distal end of the nail bed is referred to as the {{c1::hyponchium}} and is the site where the nail becomes free from the nail bed
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{{c1::thick skin with eccrine sweat glands::tissue type and glands present}}
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{{c1::Eccrine sweat glands}} are the only glands found in thick skin.
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{{c1::stratum spinosum}}
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{{c1::melanosomes in the straum spinosum}}
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{{c1::langerhans cells in the stratum spinosum::cell type and tissue layer}}
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{{c1::merkel cells}}
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{{c1::merkel cell::what is this cell? hint, it is located in epithelial tissue}}
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{{c1::meissners corpuscle in papillary dermis}}
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{{c1::pacinian corpuscle in hypodermis}}
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{{c1::eccrine sweat gland duct in thick skin::structure and tissue}}
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{{c1::apocrine sweat glands::S}}
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{{c1::peripheral nerves in the dermis}}
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Langerhans cells are of {{c1::hematopoietic (monocyte)}} origin
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what are hair follicles in terms of histology
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