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Notes in
01 Drug Receptors
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Published
07/30/2024
{{c1::Pharmacodynamics}} is the field of pharmacology focused on studying the effects of drugs and their mechanisms of action
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07/30/2024
{{c1::Receptors}} are the specific component of an organism with which drugs interact to produce changes in the functions of the system.
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07/30/2024
Increasing dosage with the unavailability of the receptor will produce {{c1::no::increased/decreased/no}} response.
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The development of new drugs would most likely target {{c1::orphan receptors::specific nature of drug receptor}}
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07/30/2024
The ligands of {{c1::Orphan::Protein/Orphan/Acceptor}} Receptors are currently {{c2::unknown::known/unknown/nonexistent}}
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07/30/2024
{{c2::Acceptor/Inert Binding Sites::Protein/Orphan/Acceptor}} Receptors do not directly influence biochemical or physiological response; ins…
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Binding with {{c1::inert}} binding sites will result to no detectable change in function of the biologic system.
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Among the natures of drug receptors, the type that can be classified under inert binding sites are the {{c1::acceptors::proteins/orphan rece…
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Among the 4 classifications of receptors, the most common and best characterized type is the {{c1::regulatory protein}}
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Most "useful" therapeutic agents tend to utilize {{c1::regulatory::regulatory/enzyme/transport/structural}} proteins as its receptor.
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The majority of enzymes are {{c1::inhibited::activated/inhibited}} by the binding of a drug.
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The administration of {{c1::Methotrexate::(drug)}} would lead to the {{c2::inhibition::stimulation/inhibition}} of {{c3::dihydrofolate …
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Sodium-Potassium ATPase is an example of a {{c1::Primary active transport::transport/enzyme/regulatory/structural}} receptor protein.
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07/30/2024
Digitalis, a drug used for congestive heart failure, binds to the {{c1::Na+/K+ ATPase::(receptor)}}, which is a {{c2::transport protein…
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07/30/2024
Colchicine, an anti-inflammatory drug used in gout patients, utilizes {{c1::Tubulin::(receptor)}}, which is classified as a {{c2::structural…
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{{c1::Effectors}} are molecules that translate the drug-receptor activity into a change in cellular activity. The most common example is {{c2::Ad…
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Another term utilized for effector molecule in pharmacology is {{c1::translator}}
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{{c1::True::True/False}}Some receptors are also effectors
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{{c1::True::True/False}}A single molecule may incorporate both the drug binding site and the effector mechanism.
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{{c1::False::True/False}}A single molecule cannot incorporate both the drug binding site and the effector mechanism. It requires two different mo…
Published
07/30/2024
{{c1::Protein::Protein/Orphan/Acceptor}} Receptors comprise the majority of receptors in the human body.
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