Notes in Common Lab Tests

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Published 09/15/2023 {{c1::sensitivity}} is calculated as the number of positive results you would get if you tested 100 patients known to have the disease = true {{c…
Published 09/13/2023 {{c1::Negative Predictive Value (NPV)}} = True negatives / True negatives + False negatives{{c3::Positive Predictive Value (PPV)}} = True positives / …
Published 09/13/2023 *If the prevalence of the disease increases, a negative result is more likely to be a FN than a TN, so NPV {{c2::decreases::increases/decreases}}*If t…
Published 09/11/2023 {{c1::positive predictive value (PPV)}} is probability that people with a positive test result truly have the outcome{{c2::negative predictive value (…
Published 09/13/2023 PPV increases with an increase in {{c1::prevalence}}{{c2::NPV}} doesn't really change much with changes in {{c1::prevalence}}at low disease preva…
Published 09/11/2023 if prevalence is low, PPV increases when the {{c1::specificity::specificity/sensitivty}} of the test increases
Published 09/13/2023 ancillary testing facilitates developing a {{c1::differential}} diagnosis → {{c1::refined}} diagnoses 
Published 09/13/2023 {{c1::60-70::range}}% of medical decision making is based on results of testing
Published 09/13/2023 Role of testing after diagnosis- prognostic: predict how disease will behave- predictive: predict which therapy may work, subset of prognostic- monito…
Published 09/13/2023 reference ranges for tests- aka. “reference intervals” or “normal ranges” - established by testing a population of individuals without {{c1::disease}}…
Published 09/13/2023 {{c3::screening}} tests: tests that detect disease in patients without {{c1::symptoms}}→ blood or urine tests→ radiology→ diagnostic procedu…
Published 09/13/2023 You should always know what the {{c1::purpose}} of a test is when you order it and what you will do with the {{c1::results}}.
Published 09/13/2023 {{c1::what}} the test is and {{c1::how}} the test is being used determines whether test is screening, diagnostic, prognostic, or therapy guiding 
Published 09/13/2023 laboratory stewardship→ only order studies that will change your {{c1::management}}*avoids undue costs to patient and health system→ factor in {{c2::p…
Published 09/13/2023 Risks of Unnecessary Testing- if lab tests are ordered without sufficient {{c1::indication}}, then monetary and personnel resources are wasted- tests …
Published 09/13/2023 {{c1::coefficient of variation (CV)}} indicates variability of test results= standard deviation (SD) divided by the mean and multiplied by 100-&n…
Published 09/13/2023 {{c1::Precision}} describes how reproducible the test is under the same conditions*you can be {{c1::precise}} but not accurate by making same error co…
Published 09/13/2023 {{c1::Basic metabolic}} panel: Sodium, Potassium, Chloride, Carbon dioxide [bicarbonate], Glucose, Calcium, Creatinine, Urea nitrogen {{c4::Compr…
Published 09/13/2023 {{c1::Therapeutic drug monitoring (TDM)}} is utilized to monitor and adjust drug doses based on measured plasma concentrations- ideal range …
Published 09/15/2023 {{c1::screening}} tests are used to assess the disease status of a large population of people with a low probability of having the disease*y…
Published 09/15/2023 Annual check-ups typically include laboratory analyses of...→ major electrolytes→ glucose→ measures of {{c2::kidney}} function→ measures of {{c2::live…
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