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Notes in
16 Neuromuscular Blockers Reversal Agents
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Published
12/13/2023
{{c2::Echothiophate}} and {{c1::organophosphates}} non-competitively inhibit acetylcholinesterase via {{c3::phosphorylation}}.
Published
12/13/2023
The primary mechanism of edrophonium is {{c1::pre}}synaptic.
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12/13/2023
Neostigmine undergoes {{c1::50}}% renal and {{c1::50}}% liver metabolism/elimination.
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12/13/2023
Edrophonium undergoes {{c1::75}}% renal and {{c1::25}}% liver metabolism/elimination.
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12/13/2023
Pyridostigmine undergoes {{c1::75}}% renal and {{c1::25}}% liver metabolism/elimination.
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12/13/2023
The dose of pyridostigmine for reversal of neuromuscular blockade is {{c1::0.1}} - {{c1::0.3}} mg/kg.
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12/13/2023
The onset of pyridostigmine for reversal of neuromuscular blockade is {{c1::10}} - {{c1::20}} min.
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12/13/2023
The duration of pyridostigmine for reversal of neuromuscular blockade is {{c1::60}}-{{c1::120}} min.
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12/13/2023
The anticholinergic of choice for pyridostigmine is {{c1::glycopyrrolate}}.
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12/13/2023
The dose of cholinesterase inhibitors should be {{c1::unchanged}} in renal failure.
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12/13/2023
Mixing cholinesterase inhibitors produces {{c1::additive}} effects.
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12/13/2023
Neostigmine has a faster reversal time in {{c1::pediatric}} patients.
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12/13/2023
What cholinesterase inhibitor can be used to reduce the incidence of postoperative shivering?{{c1::Physostigmine}}
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12/13/2023
What cholinesterase inhibitor can be used for intrathecal analgesia?{{c1::Neostigmine}}
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12/13/2023
Anticholinergic drugs {{c1::do not affect}} the heart rate in patients with a heart transplant.
Published
12/13/2023
The side effects of {{c1::acetylcholinesterase inhibitors}} can be remembered with the mnemonic "DUMBBELLS":D: {{c2::Diarrhea}}U: {{c3::Urination}}M: …
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