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Enzyme Catalysis
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Last Update
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Published
09/07/2023
What are the two key features of enzymes in general?
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09/07/2023
Enzymatic rate of reaction depends on what?
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If concentration of substrate (S) is infinitely high, what is the enzymatic rate of reaction?
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Vmax and Kcat are used to describe the ___ of the enzyme.
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What is Km?
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Km describes the ___ of the enzyme to the substrate, and ___ Km values suggest tighter binding.
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Enzymatic rate enhancements are explained by the enzymes' ability to ______
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What is activation energy?
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The ____ the free energy of the transition state relative to the energy of the substrate, the ___ the reaction.
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How do enzymes lower activation energy barriers?
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True or false: enzymes alter the free energy of the substrate and products
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09/07/2023
OMP decarbozylase catalyzes OMP to UMP for what metabolic purpose?
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09/07/2023
OMP decarboxylase uses which enzyme-substrate interaction to stabilize the transition state of OMP?
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09/07/2023
True or false: The interactions between enzymes and substrates are mediated by many transient covalent bonds, which are also used to drive catalysis a…
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09/07/2023
What is the induced fit model?
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09/07/2023
If substrates can be bound to enzymes with weak interactions like hydrogen bonds, how is the overall interaction strong?
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09/07/2023
How does OMP decarboxylase exemplify the close relationship between substrate recognition and catalytic rate enhancement?
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09/07/2023
What are the 4 classes of enzyme inhibitors?
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09/07/2023
How is the potency of inhibitors quantified?
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09/07/2023
Describe competitive inhibitors
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How do competitive inhibitors affect Km and Vmax
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Describe mixed inhibition
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What is noncompetitive inhibition?
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How does noncompetitive inhibition affect Vmax and Km?
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How does mixed inhibition affect Km and Vmax?
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09/07/2023
What is uncompetitive inhibition?
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How does uncompetitive inhibition affect Vmax and Km?
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09/07/2023
How do mechanism based inhibitors work?
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09/07/2023
What kind of inhibitor is DIPF and what does it inhibit?
Published
09/07/2023
Mechanism based inhibition refers to ___ inhibitors.
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