Notes in Year 01 Semester 03

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Published	12/13/2023	5 functions of bones
Published	12/13/2023	Shaft and end of bones are called
Published	12/13/2023	Medullary canal contains mostly
Published	12/13/2023	Red marrow which is … is located mostly in the …
Published	12/13/2023	Epiphysis plate is
Published	12/13/2023	Epiphyseal line
Published	12/13/2023	Bone is made of 2/3 … and 1/3 …
Published	12/13/2023	What gives bones it’s hardness
Published	12/13/2023	{{c1::Calcium phosphate}} which reacts with {{c2::calcium hydroxide}} to form {{c3::hydroxyapatite}}
Published	12/13/2023	What gives bones their flexibility
Published	12/13/2023	Collagen requires… to be produced
Published	12/13/2023	Calcium is regulated by what other system
Published	12/13/2023	What hormone causes an increase in blood calcium levels
Published	12/13/2023	PTH does what?
Published	12/13/2023	Calcitrol
Published	12/13/2023	Calcitonin does what
Published	12/13/2023	If can’t make activated Vit D you get bones that are
Published	12/13/2023	More positive charge exists in the …cellular fluid
Published	12/13/2023	More negative charges exist in the … cellular fluid
Published	12/13/2023	Where do charges exist in the cellular spaces
Published	12/13/2023	Whats membrane potential/voltage
Published	12/13/2023	Depolarization in AP is what movement
Published	12/13/2023	Repolarization is what in AP
Published	12/13/2023	A nerve is
Published	12/13/2023	Neuromuscular junction is composed of
Published	12/13/2023	What is the synaptic cleft
Published	12/13/2023	What is subneural cleft
Published	12/13/2023	Where are nAChr found in NMJ?
Published	12/13/2023	nAch are (NMJ context)
Published	12/13/2023	In NMJ where are the voltage gated ion channels
Published	12/13/2023	In the NMJ where are large quantities of AChE found?
Published	12/13/2023	what covers the diaphysis, the epiphysis of long bones?
Published	12/13/2023	loss of estrogen post menopausally result in what changes to calcium
Published	12/13/2023	calcitonin is secreted from where
Published	12/13/2023	what are steps of calcitriol synthesis
Published	12/13/2023	What causes paralysis by affecting motor end plate?
Published	12/13/2023	How does Succ work
Published	12/13/2023	how does Nondepolarizing meds work
Published	12/13/2023	after action potential at NMJ or End plate
Published	12/13/2023	T tubules run along side what structure of the Myofiber
Published	12/13/2023	SR is storage for
Published	12/13/2023	AP causes what in Myofiber
Published	12/13/2023	Ratio of T tubules to SR
Published	12/13/2023	AP along T tubule causes what to change
Published	12/13/2023	voltage change from AP in t tubles causes what - Skeletal muscle
Published	12/13/2023	L type calcium channels are also called
Published	12/13/2023	how do DHP channels (Ltype channels) work - skeletal muscle
Published	12/13/2023	L type calcium channels are mechanical bonded to what channel
Published	12/13/2023	what is the coupuling of DHP/Ltype Ca channels in skeletal muscle called
Published	12/13/2023	Ca allows for muscle contraction how
Published	12/13/2023	how is calcium removed from the interstital space after release by SR
Published	12/13/2023	what do you need for muscle relaxation
Published	12/13/2023	Fasciculation
Published	12/13/2023	paralysis
Published	12/13/2023	paresis
Published	12/13/2023	spasticity vs flaccidity
Published	12/13/2023	Malignant Hyperthermia happens more in
Published	12/13/2023	What causes/triggers Malignant Hyperthermia - drug
Published	12/13/2023	what is physiological basis for MH
Published	12/13/2023	What is the sequence of events for MH
Published	12/13/2023	you see a surge of {{c1::CO2}} in MH because of a increase in ATP usage and thus and increase in {{c1::Cellular Respiration}}
Published	12/13/2023	the surge in CO2 from MH causes a {{c1::respiratory acidosis }}
Published	12/13/2023	HM starts out as {{c1::aerobic}} respiration but changes to {{c1::anaerobic}} respiration because of the usage of {{c2::lots of ATP}} this causes a …
Published	12/13/2023	what physical signs do you see with MH?{{c1::masseter rigidity -> general rigidityhyperthermiamyoglobinuria - cola colored urine }}
Published	12/13/2023	eventually if not treated MH leads to  depletion of {{c1::ATP}} leading to {{c2::cell death}} causing {{c1::cell lysis}} and release of {{c2::K…
Published	12/13/2023	why does rhabdomyolysis lead to cola colored urine?
Published	12/13/2023	what drug do you give to MH and what does it do
Published	12/13/2023	Dantrolene is excellent because
Published	12/13/2023	contusion
Published	12/13/2023	hematoma
Published	12/13/2023	laceration
Published	12/13/2023	strain
Published	12/13/2023	sprain
Published	12/13/2023	dislocation
Published	12/13/2023	subluxation
Published	12/13/2023	fracture
Published	12/13/2023	Arthro/Articul-
Published	12/13/2023	articulations
Published	12/13/2023	what is purpose of articulations of bones
Published	12/13/2023	3 categories of joints
Published	12/13/2023	synarthrosis
Published	12/13/2023	amphiarthrosis
Published	12/13/2023	Diarthrosis
Published	12/13/2023	synovial joints all have {{c1::articular capsule}} lined by {{c1::synovial membrane}} and filled with {{c1::synovial fluid}}. where bones articulate t…
Published	12/13/2023	articular cartilage
Published	12/13/2023	synovial membrane
Published	12/13/2023	synovial fluid is made of
Published	12/13/2023	extra anatomy that are found in some (not all) synovial joints
Published	12/13/2023	meniscus
Published	12/13/2023	bursa
Published	12/13/2023	intracapsular ligaments
Published	12/13/2023	tendon connects
Published	12/13/2023	ligament attaches
Published	12/13/2023	grades of sprains are based on
Published	12/13/2023	compartment syndrom is a complication of ...
Published	12/13/2023	what are signs of presentation of compartment syndrom
Published	12/13/2023	thromboembolism from fracture often from fx of
Published	12/13/2023	the thromobus see from limb fracture is
Published	12/13/2023	fat embolism etiology is thought to be from
Published	12/13/2023	what are signs and symptoms of fat embolism
Published	12/13/2023	osteomyelitis two origination stories
Published	12/13/2023	continguous spread osteomyelitis
Published	12/13/2023	hematogenous osteomyelitis
Published	12/13/2023	what is osteonecrosis
Published	12/13/2023	one of the most common cause of osteonecrosis
Published	12/13/2023	osteopenia
Published	12/13/2023	osteoporosis
Published	12/13/2023	osteopetrosis
Published	12/13/2023	dysminerlization
Published	12/13/2023	Osteomalacia and Rickets
Published	12/13/2023	what is example of dysmineralization metabolic bone disease
Published	12/13/2023	paget disease
Published	12/13/2023	activity tolerance
Published	12/13/2023	intolerance
Published	12/13/2023	fatigue
Published	12/13/2023	acute physical fatigue
Published	12/13/2023	chronic fatigue
Published	12/13/2023	rheumatology
Published	12/13/2023	rheumatism
Published	12/13/2023	Arthritis
Published	12/13/2023	what are the 4 categories of rheumatisim
Published	12/13/2023	Systemic autoimmune rheumatic diseases connective tissues is every where so systemic means {{c1::diffuse inflammation}} lesions and {{c1::degenerative…
Published	12/13/2023	Systemic lupus erythematosus {{c1::85}}% female etiology make {{c1::antinuclear}} antibodies - {{c1::Bcell}} dysfunction against {{c1::own DNA}} s…
Published	12/13/2023	Rheumatoid arthritis {{c1::exemplar}} systemic rheumatic disease more common in Females 3:1 {{c1::1-2}}% of pop etiology combo of {{c1::genetic}} a…
Published	12/13/2023	osteoarthritis syndrome {{c1::degenerative}} joint disease joint {{c1::inflammation}} caused by {{c1::mechanical}} stress bone and cartilage break …
Published	12/13/2023	crystal induced arthropathies {{c1::gout}} classic example {{c1::precipitation}} of crystals from inability to breakdown
Published	12/13/2023	seronegative {{c1::spondyloarthropathies}} {{c1::systemic}} immune disorders no {{c1::RF}} however tend to specifically effect {{c1::spine}}
Published	12/13/2023	pharmacokinetics
Published	12/13/2023	pharmacodynamics
Published	12/13/2023	total body water is {{c1::42L}} {{c1::2/3}} intra ~{{c1::28L}} {{c1::1/3}} extra cellular ~ {{c1::14}} L {{c1::3/4}} interstitial ~ {{c1::10.5}}L …
Published	12/13/2023	oncotic pressure
Published	12/13/2023	starling equation says ... is equal to ... and ...
Published	12/13/2023	lipid / water partition coefficient
Published	12/13/2023	the magnitiue of drug recetor complex response is dependent upon
Published	12/13/2023	receptors exist in what forms
Published	12/13/2023	upregulation of receptors
Published	12/13/2023	down regulation of receptors
Published	12/13/2023	Receptor proteins can be
Published	12/13/2023	do all drugs effect receptor proteins
Published	12/13/2023	if drug binds to receptor and causes action what are the two effects that can happen
Published	12/13/2023	what effects can drugs have on receptor proteins
Published	12/13/2023	proteins and effects {{c1::antagonistic}} where there is no effect because the receptor is blocked from being active “{{c1::neutral}}” on graph {{…
Published	12/13/2023	when talking about binding of receptor to drug what kind of bond is it? {{c1::reversible}} weak and easily broken van der walls {{c1::hydrogen}} io…
Published	12/13/2023	4 basic receptor types
Published	12/13/2023	4c264dbdcbad4befa2a4a4a0b57893f6-oa-1
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Published	12/13/2023	4c264dbdcbad4befa2a4a4a0b57893f6-oa-5
Published	12/13/2023	4c264dbdcbad4befa2a4a4a0b57893f6-oa-6
Published	12/13/2023	4c264dbdcbad4befa2a4a4a0b57893f6-oa-7
Published	12/13/2023	4c264dbdcbad4befa2a4a4a0b57893f6-oa-8
Published	12/13/2023	4c264dbdcbad4befa2a4a4a0b57893f6-oa-9
Published	12/13/2023	pharmacokinetics encompasses what four stages
Published	12/13/2023	what overarching term tells us about the concentration of a drug in plasma or at site of effect?
Published	12/13/2023	drugs that are eliminated as a certain percentage over time are following what model of elimination
Published	12/13/2023	first order elimination is dependent upon what
Published	12/13/2023	if a certain amount of drug is cleared after a unit time this drug follow what model for elimination and why
Published	12/13/2023	what are examples of zero order drugs
Published	12/13/2023	a model that looks at all the different components of the body and how their volumes and spaces effect pharmacokinetics is the
Published	12/13/2023	if you give a bolus theoretically into the one compartment model what do you see
Published	12/13/2023	what is infusion goal in regards to the compartment models and what happens if you overshoot or under shoot that goal
Published	12/13/2023	describe the movement of a drug in the multicompartment model and why it's more realistic
Published	12/13/2023	hellow
Status	Last Update	Fields