Notes in C. Neoplastic proliferation

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Published 10/21/2024 {{c1::MYC}} is activated in germinal center B-cell lymphomas by translocations to the transcriptionally active Ig locus.
Published 10/21/2024 {{c1::Epstein-Barr virus (EBV)}} is associated with a subset of Burkitt lymphoma, Hodgkin lymphoma, and many B-cell lymphomas in immunodeficiency.
Published 10/21/2024 {{c1::H. pylori}} infection is linked to gastric B-cell lymphoma.
Published 10/21/2024 {{c1::Bloom syndrome}}, Fanconi anemia, and ataxia telangiectasia are inherited genetic factors that increase the risk of acute leukemia.
Published 10/21/2024 Leukemias are neoplasms that present with widespread involvement of the {{c1::bone marrow}} and (usually) the {{c1::peripheral blood}}.
Published 10/21/2024 Plasma cell neoplasms often arise in the {{c1::bone marrow}} and only infrequently involve the {{c1::lymph nodes}} or peripheral blood.
Published 10/21/2024 Lymphocytic leukemias cause signs and symptoms related to the suppression of normal {{c1::hematopoiesis}} by tumor cells in the {{c1::bone marrow}}.
Published 10/21/2024 Lymphoid neoplasms are often associated with immune abnormalities, and most resemble some recognizable stage of {{c1::B-cell}} or {{c1::T-cell}} diffe…
Published 10/21/2024 Lymphoma staging is most useful in guiding therapy for {{c1::Hodgkin lymphoma}} but is less useful for most forms of {{c1::NHL}}
Published 10/21/2024 Neoplastic B and T cells tend to recapitulate the behavior of their {{c1::normal}} counterparts and are often associated with {{c1::immune}} abnormali…
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