Notes in 03 Hemostasis & Thrombosis

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Published 07/30/2024 Events of Primary Hemostasis:{{c1::VasoconstrictionPlatelet ActivationPlatelet Plug Formation::3}}
Published 07/30/2024 Fibrin formation occurs during {{c1::seconda}}ry hemostasis
Published 07/30/2024 Fibrinolysis occurs during {{c1::tertia}}ry hemostasis
Published 07/30/2024 [VR]1. PG{{c1::I2}}2. Platelet activation and aggregation{{c2::B}}
Published 07/30/2024 {{c1::Heparan sulfate}} activates {{c2::antithrombin III}}, which directly inhibits {{c3::thrombin and activated factor X::2}}
Published 07/30/2024 Resting Platelet Shape: DiscoidActivated Platelet Shape: {{c1::Pseudopod extensions}}
Published 07/30/2024 Platelets are activated when they encounter {{c1::collagen}}
Published 07/30/2024 Alpha Granules Content:{{c1::Adhesion moleculesCoagulation proteinsFibrinolytic proteins::3}}
Published 07/30/2024 Dense Granules Content:{{c1::NucleotidesCa::2}}
Published 07/30/2024 GP {{c1::Ib/IX/V complex}} binds to vWF on collagen
Published 07/30/2024 GP {{c1::Ia/IIA (integrin a2B1) and VI}} binds to collagen
Published 07/30/2024 GP {{c1::IIB/IIIA (integrin a2B3)}} binds to free fibrinogen and vWF
Published 07/30/2024 Platelet {{c2::Ca}} causes the release of {{c1::TXA2}} which attracts platelets for aggregation and the exposure of GP {{c1::IIa/IIIa}}
Published 07/30/2024 Most of the coagulation factors come from the liver, except:Factor {{c1::3}} from {{c2::Damaged tissue and activated platelets}}Factor {{c1::4}} from …
Published 07/30/2024 In secondary hemostasis, there is no factor {{c1::VI}}
Published 07/30/2024 Mnemonic for Vitamin K Dependent Factors: {{c1::1972 + C}}
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