Notes in Tissue Development

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Status	Last Update	Fields
Published	09/06/2023	What are the three categories used to classify the regenerative capacity of tissues?
Published	09/06/2023	How do labile tissue regenerate so quickly?
Published	09/06/2023	How do stable tissues regenerate?
Published	09/06/2023	How do permanent tissues heal?
Published	09/06/2023	Primary intention healing of skin
Published	09/06/2023	Secondary intention healing of skin
Published	09/06/2023	Tertiary intention healing of skin
Published	09/06/2023	The predicatable set of stages in wound healing are {{c1::hemostasis, inflammation, epithelialization, fibroplasia, and maturation}} (5 step…
Published	09/06/2023	{{c1::Hemostasis}} is the prevention of {{c2::further blood loss }} through coagulation and other intracellular pathways
Published	09/06/2023	Process of hemostasis
Published	09/06/2023	Damaged cells releases {{c1::chemokines and cytokines}} to recruit {{c2::immune cells, macrophages, and neutrophils}} and make nearby blood …
Published	09/06/2023	A {{c1::scab}} is the combination of the blood clot, dead macrophages, and cellular debris at site of injury.
Published	09/06/2023	Process of epithelialization
Published	09/06/2023	Process of fibroplasia
Published	09/06/2023	Steps of wound maturation
Published	09/06/2023	{{c1::Collagen cross linking}} occurs when bonds form between collagen bundles, enhancing the tensile strength of the wound.
Published	09/06/2023	{{c1::Collagen remodeling}} occurs when fibroblasts degrade old or misshapen collagen from the injury.
Published	09/06/2023	{{c1::Contraction}} occurs when {{c2::myofibroblasts}} produce contractile proteins within the cell
Published	09/06/2023	{{c1::Repigmentation}} occurs when {{c2::melanocytes}} begin to proliferate and restore the normal color to damaged skin.
Published	09/06/2023	Wound healing can be hindered by {{c1::decreased circulation}}, {{c1::infection}}, and {{c1::edema}}
Published	09/07/2023	Cells have two main methods of death: {{c1::apoptosis}} and {{c1::necrosis}}
Published	09/07/2023	{{c1::Ischemia}} is an inadequate blood supply to an organ or part of the body
Published	09/07/2023	Intrinsic mitochondrial pathway
Published	09/07/2023	Extrinsic/death receptor pathway of apoptosis
Published	09/07/2023	function of caspases
Published	09/07/2023	Oncosis
Published	09/07/2023	Explain how acute inflammation generally resolves:
Published	09/07/2023	Explain how chronic inflammation generally resolves:
Published	09/07/2023	Function of the paranasal sinuses
Published	09/07/2023	{{c1::Sympathetic nerves}} stimulate {{c2::beta 2 adrenergic receptors}} and {{c3::increase}} the diameter of the airways
Published	09/07/2023	{{c1::Parasympathetic}} nerves stimulate the {{c2::muscarinic}} receptors, causing a {{c3::decrease}} in the diameter of airways.
Published	09/07/2023	{{c2::Goblet cells}} secrete {{c1::mucus}} and help facilitate the {{c3::mucociliary escalator}}
Published	09/07/2023	{{c1::Club cells}} secrete {{c2::glycosaminoglycans}} to protect the bronchiolar epithelium
Published	09/07/2023	Hematocrit is the measure of {{c1::red blood cells by volume}} in blood
Published	09/07/2023	Red blood cells are {{c1::biconcave}} in shape to maximize {{c2::surface area}} for gas exchange
Published	09/07/2023	{{c1::Megakaryocytes}} produces {{c2::platelets}} in the bone marrow
Published	09/07/2023	The most abundant protein found in blood is {{c1::albumin.}}
Published	09/07/2023	General function of albumin in the bloodstream
Published	09/07/2023	Removal of {{c1::clotting factor proteins}} from {{c2::plasma}} results in {{c3::serum}}.
Published	09/07/2023	{{c1::Electrolytes}} maintain normal acid base physiology in the blood and help regulate blood osmolarity
Published	09/07/2023	{{c1::Fibrinogen}} helps platelets attach to one another to form the {{c2::platelet plug}}
Published	09/07/2023	{{c1::Erythropoietin}} stimulates the {{c2::production of erythrocytes}} in the bone marrow
Published	09/07/2023	Erythropoietin binds to receptors on {{c1::immature red blood cells (erythroclasts)}} resulting in maturation into {{c2::erythrocytes.}}
Published	09/07/2023	In the {{c1::presence of oxygen}}, {{c2::HIF-prolyl hydroxylase}} acts on the alpha subunit of {{c3::HIF1}} allowing it to be further {{c3::ubiquitina…
Published	09/07/2023	HIF1
Published	09/07/2023	When there is {{c1::decreased oxygen delivery}} to the tissues, the kidneys increase {{c2::erythropoietin }}production.
Published	09/07/2023	In {{c2::secondary hemostasis}}, the {{c1::platelet plug}} is reinforced by a protein mesh of {{c3::fibrin}}.
Published	09/07/2023	{{c1::Vascular spasm}} is the reflexive contraction of smooth muscle at the site of injury
Published	09/07/2023	Following endothelial injury, secretion of {{c1::nitric oxide and prostaglandins}} decreases, and {{c2::endothelin secretion}} increases instead to co…
Published	09/07/2023	Damaged endothelial cells release {{c1::Von Willebrand's factor}} which binds to {{c2::exposed collagen}}
Published	09/07/2023	Platelets use {{c1::GP1B}} (a surface protein) to bind to the {{c2::Von Willebrand factor protein}}
Published	09/07/2023	Activated platelets relase {{c1::ADP and thromboxane A2}} to activate unbound platelets creating a {{c2::positive feedback loop}}
Published	09/07/2023	{{c1::Prostaglandins and NO}} secreted by {{c2::undamaged}} endothelial cells prevents {{c3::widespread platelet activation}}
Published	09/07/2023	{{c1::GPIIB/IIIA}} is newly expressed on the surface of activated platelets after  ADP and thromboxane A2 bind.
Published	09/07/2023	{{c1::GPIIB/IIIA}} binds to {{c2::fibrinogen}} which brings two platelets together
Published	09/07/2023	During {{c1::secondary hemostasis,}} {{c2::fibrinogen}} gets cleaved into {{c3::fibrin}}, forming a mesh around the platelet plug for support.
Published	09/07/2023	When 2,3-DPG is bound to hemoglobin, it stabilizes the {{c1::T-state conformation}} and {{c2::decreases}} hemoglobin affinity for oxygen, leads to {{c…
Published	09/07/2023	A {{c1::white blood cell differential}} is a lab test that provides information about different types of WBCs in a patient's blood.
Published	09/07/2023	The Coulter principle of cell counting
Published	09/07/2023	{{c2::Type II pneumocytes}} have the ability to secrete {{c1::surfactants}}
Published	09/07/2023	The large airways are lined by two cell types: {{c1::ciliated columnar cells and goblet cells.}}
Published	09/07/2023	Walls of the conducting bronchioles are lined by {{c1::ciliated columnar cells}}, {{c1::goblet cells}}, and {{c1::club cells}} (three m…
Published	09/07/2023	Alveolar wall mainly consists of {{c1::thin epithelial cells}} (pneumocytes).
Published	09/07/2023	The bronchi has a layer of {{c1::smooth muscle}} between the {{c2::lamina propria}} and {{c2::submucosa}}, which is responsible for {{c3::broncho…
Published	09/07/2023	Five cell types in the conducting airway epithelium
Published	09/07/2023	In the {{c1::terminal bronchioles}}, the {{c2::pseuodstratified epithelium}} starts transitioning into {{c3::simple columnar cells}}
Published	09/07/2023	Components of the respiratory bronchioles
Published	09/07/2023	Components of the alveolar ducts
Published	09/07/2023	Purpose of the Pore of Kohn
Published	09/08/2023	Club (Clara) cells differentiating features:
Published	09/07/2023	Type 1 pneumocyte description
Published	09/07/2023	Type II pneumocyte description
Published	09/08/2023	651f5777bb3640f5aaa142478934bcc4-ao-5
Published	09/08/2023	98c6cef39c19493f81808e8427d4674b-oa-2
Status	Last Update	Fields