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Notes in
31 Coagulation
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Published
12/13/2023
Classic hemophilia presents with a {{c1::normal}} PT and bleeding time and a {{c1::prolonged}} aPTT.
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12/13/2023
{{c2::Prothrombin time (PT)}} measures the {{c1::extrinsic}} and common pathways of coagulation
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12/13/2023
The extrinsic pathway of coagulation consists of factors {{c1::III and VII}}.
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12/13/2023
The intrinsic pathway of coagulation consists of factors {{c1::XII, XI, IX, and VIII}}.
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12/13/2023
{{c2::DDAVP (desmopressin)::drug}} increases the production of {{c1::von Willebrand's factor::factor}}
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12/13/2023
A normal adult value for PT is {{c1::10-14 seconds}}
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12/13/2023
A normal adult value for INR is {{c1::1.0}}
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12/13/2023
A normal adult value for APTT is {{c1::25-32 seconds}}
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12/13/2023
The production of {{c1::thrombin}} in the coagulation cascade will result in a positive feedback loop and accelerate coagulation.
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12/13/2023
The common pathway of coagulation consists of factors {{c1::X, V, II, I, and XIII}}.
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12/13/2023
What procoagulant factors are synthesized in the blood vessel endothelium?{{c1::Factor VIII, von willebrand factor::2}}
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12/13/2023
Heparin is primarily synthesized by {{c2::mast cells}} in the {{c1::lungs}}.
Published
12/13/2023
Protein C and S and {{c1::anti}}coagulants.
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