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Notes in
NAS VII (Neuromuscular junction)
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Published
11/11/2024
The {{c1::NMJ}} is a {{c2::specialised synapse}} between {{c2::a motor neurone's axon}} and {{c2::muscle cell}} and is also known as an {{c2…
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The synaptic cleft has a high concentration of {{c1::Acetylcholinesterase}}/{{c1::AChE}} which {{c2::breaks down the neurotransmitter after it has ini…
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The muscle fibre’s plasma membrane is highly infolded, the infolds are called {{c1::postjunctional folds}}. These folds {{c1::increase the surface are…
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There is a {{c1::high concentration of nicotinic Acetylcholine receptors}} on the top of those infolds.
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Acetylcholine binds to {{c1::ionotropic nicotinic receptor}} on the plasma membrane of the muscle cell, causing {{c1::the ion channels}} to …
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In the NMJ, More {{c1::sodium}} leaves than {{c1::potassium}} enter as the initial potential is closer to E{{c1::K+}} than E{{c1::Na+}} and …
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An increase in muscle force is achieved by {{c1::temporal summation}} at the NMJ, which {{c1::means an increased frequency of motor neurone neurotrans…
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