Notes in Week 4

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Published 09/19/2023 {{c1::Chest pain}} is the most common reason for ECG in children
Published 09/19/2023 6 major categories of heart issues{{c1::coronary}}: ischemia --> acute MI{{c2::muscle}}: squeeze --> blood pressure{{c3::rhythm}}: palpitations …
Published 09/19/2023 {{c1::Angioplasty}} is the process of using a balloon to remove a blood clot
Published 09/19/2023 {{c1::Cardiac Output}} = {{c2::Heart Rate}} * {{c3::Stroke Volume}}
Published 09/19/2023 {{c1::Mean Arterial Pressure}} - {{c2::Central Venous Pressure}} = {{c3::Cardiac Output}} * {{c4::Systemic Vascular Resistance}}
Published 09/19/2023 {{c1::ΔP}} = {{c2::Flow (Q)}} * {{c3::Resistance (R)}}
Published 09/19/2023 The blood pressure equation is most analogous to {{c1::Ohm's law}}
Published 09/19/2023 Arteries have {{c1::higher}} pressure and {{c1::low}} compliance (volume)
Published 09/19/2023 Veins have {{c1::lower}} pressure and {{c1::high}} compliance (volume)
Published 09/19/2023 The three layers of the vessels are{{c1::Intima}}: endothelial{{c2::Media}}: smooth muscle{{c3::Adventitia}}: connective tissue, vaso vasorum
Published 09/19/2023 {{c1::Stroke Volume}} = {{c2::Left ventricular end diastolic volume (LVEDV)}} - {{c3::Left ventricular end systolic volume (LVESV)}}
Published 09/19/2023 {{c1::Ejection Fraction}} = {{c2::Stroke Volume}}/{{c3::LVEDV}}
Published 09/19/2023 {{c1::Endothelial}} factors lead to {{c2::vasoconstriction}} of {{c3::smooth muscle}}
Published 09/19/2023 Veins might require {{c1::manual pressure}} to perform {{c2::hemostasis}}
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Published 09/19/2023 The neurotransmitter released by the {{c2::preganglionic neuron}} of both the sympathetic and parasympathetic nervous system is {{c1::acetylcholi…
Published 09/19/2023 Most postganglionic neurons of the sympathetic nervous system release {{c1::catecholamines}} (Eg. {{c2::adrenaline}} and {{c2::noradren…
Published 09/19/2023 A few postganglionic neurons of the sympathetic nervous system release {{c1::acetylcholine}}, which bind to {{c2::muscarinic receptors}}
Published 09/19/2023 alpha-1 receptors affect:{{c1::walls}} of blood vessels{{c2::urinary}} retention{{c3::mydriasis}}{{c4::ejaculation}}
Published 09/19/2023 alpha-2 receptor effect:{{c1::decrease}} effect of sympathetic nervous system
Published 09/19/2023 Beta-1 receptors are responsible for:Increased {{c1::heart rate}} and {{c1::contractility}}Release of {{c2::renin}}
Published 09/19/2023 Beta-2 receptors are responsible for:Secretion of {{c1::aqueous humor}}More {{c2::glucose}}Release of {{c3::glucagon}}{{c4::Bronchodila…
Published 09/19/2023 Postganglionic parasympathetic neurons release {{c1::acetylcholine}} which binds to {{c2::muscarinic receptors}}
Published 09/19/2023 {{c1::Nicotinic::nicotinic/muscarinic}} receptors are {{c2::ligand-gated ion channels}} while {{c1::muscarinic::nicotinic/muscarinic}} recep…
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Published 09/20/2023 Sympathetic nervous system agonists include:{{c1::Direct}} agonists: {{c2::alpha}} and {{c3::beta}} agonists (can be {{c4::non-selectiv…
Published 09/20/2023 Sympathetic Nervous System Antagonists:{{c1::Presynaptic}} adrenergic antagonist: {{c3::Central}} and {{c3::peripheral}}{{c1::Postsynaptic}} adre…
Published 09/19/2023 Parasympathetic Agonists:{{c1::Direct}} cholinomimetic: mimics {{c2::acetylcholine}}{{c1::Indirect}} cholinomimetic: {{c3::anticholinesteras…
Published 09/19/2023 Parasympathetic Antagonists:{{c1::Muscarinic}} antagonist: inhibits effect of {{c2::acetylcholine}}
Published 09/20/2023 Low {{c1::blood vessel resistance}} leads to less {{c2::perfusion}} (less time for O2 exchange)
Published 09/19/2023 The types of shock are:{{c1::hypovolemic}}{{c2::cardiogenic}}{{c3::obstructive}}{{c4::distributive}}
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Published 09/19/2023 Distributive resistance includes {{c1::septic}} and {{c1::anaphylactic}} shock
Published 09/19/2023 {{c1::MVO2}} is the measure of {{c2::leftover oxygen}}
Published 09/19/2023 During the adhesion step, von willebrand's factor binds to the {{c1::Gp1b}} receptor on platelets
Published 09/19/2023 During the activation step, {{c1::ADP}} and {{c1::TXA2}} is released which activates {{c2::platelets}} in the periphery and leads to gr…
Published 09/19/2023 The extrinsic pathway of secondary hemostasis:Cleavage of {{c1::III}} --> combines with cleaved {{c2::VII}} --> cleaves {{c3::X}}…
Published 09/19/2023 Common pathway of secondary hemostasis:Cleavage of {{c1::X}} and {{c1::V}} --> cleavage of {{c2::II}} --> cleavage of {{c3::…
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Published 09/20/2023 Factor {{c1::IIa}} (thrombin) activates platelets and the factors {{c2::V}}, {{c2::VIII}}, and {{c2::XIII}}
Published 09/19/2023 Factors {{c1::Xa}} and {{c1::Va}} combine to form the {{c2::prothrombinase}} complex, which cleaves factor {{c3::II}} to its active for…
Published 09/20/2023 When excess thrombin binds to {{c3::thrombomodulin}}, it complexes with proteins {{c1::C}} and {{c1::S}}, inhibiting complexes {{c2::V}…
Published 09/20/2023 Antithrombin binds to {{c1::thrombin}} and {{c1::X}} and inhibits factors {{c2::II}}, {{c2::IX}}, {{c2::X}}, {{c2::XI}}, and&…
Published 09/19/2023 Clot retraction:The platelet {{c1::lamellipodia}} contract and brinds the edges of wound closerHappens by activation of integrin {{c2::aIIbB…
Published 09/20/2023 Fibrinolysis occurs when {{c1::plasminogen}} is converted to {{c1::plasmin}} via the {{c2::tissue plasminogen activator (tPA)}}
Published 09/19/2023 Heparin mechanism of action: potentiation of {{c1::antithrombin III}}
Published 09/19/2023 {{c2::Warfarin}} MOA: inhibits {{c1::vitamin K epoxide reductase}}
Published 09/19/2023 Rivaroxaban, apixaban, edoxaban MOA: inhibits factor {{c1::Xa}}
Published 09/19/2023 Dabigatran and bivalirudin MOA: direct {{c1::thrombin (factor IIa)}} inhibitor
Published 09/20/2023 Another word for {{c1::adrenergic agonists}} is {{c2::"pressors"}}
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Published 09/20/2023 {{c1::Distributive}} shock is characterized by {{c2::decreased}} systemic vascular reflex
Published 09/20/2023 {{c1::Septic}} shock is a large {{c2::inflammatory}} response that leads to vasodilation and capillary leak.Characterized by {{c3::hypo}}ten…
Published 09/20/2023 {{c1::Anaphylactic}} shock is a large {{c2::histamine}} release that leads to vasodilation and capillary leak.Characterized by {{c3::hypo}}t…
Published 09/20/2023 {{c1::Neurogenic}} shock is a loss of {{c2::sympathetic tone}} due to damaged {{c4::autonomic}} pathways in the spinal cord. Characterized b…
Published 09/20/2023 3 functions of nephron:{{c1::Excreting}} waste{{c2::Reclaiming}} filtered fluid/solutes{{c3::Fine-tuning}} the filtrate
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Published 09/20/2023 The glomerular filtration barrier selectively filters molecules based on:{{c1::Size}}{{c2::Charge}}{{c3::Transcapillary pressure}}
Published 09/20/2023 {{c1::Negatively}} charged molecules don't filter well bc the filtration barrier is {{c1::negatively}} charged
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Published 09/20/2023 The {{c1::Na/K ATPase}} in the PCT generates an {{c2::electrochemical}} gradient for solute transport
Published 09/20/2023 Answer: {{c1::Increase}}
Published 09/20/2023 Answer: {{c1::Yes}}
Published 09/20/2023 The {{c1::descending}} loop of Henle primarily is responsible for reabsorption of {{c2::water}}
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Published 09/27/2023 {{c1::Loop diuretics}} reduce {{c2::sodium}} reabsorption, which leads to elimination of {{c3::water}}. Useful in cases of {{c4::fluid …
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Published 09/20/2023 {{c1::Thiazides}} inhibit the {{c2::NaCl cotransporter}}
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Published 09/20/2023 {{c1::Aldosterone}} binds to {{c2::mineralocorticoid}} receptors, which increase {{c3::Na+}} reabsorption. This leads to greater {{c4::…
Published 09/20/2023 {{c1::Hyper}}aldosteronism is associated with {{c2::hypo}}kalemia
Published 09/24/2023 A rise in {{c2::plasma osmolality}} triggers {{c1::ADH}} release. This acts on its receptor to phosphorylate {{c3::aquaporin-2}} and lead to&nbsp…
Published 09/20/2023 Answer: {{c1::B}}
Published 09/20/2023 Answer: {{c1::Polyuria}}
Published 09/20/2023 Steps of fetal heart development{{c1::Primary heart field}} --> {{c2::paired endocardial heart tubes form}} --> {{c3::body folding}} -…
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Published 09/20/2023 The heart normally loops to the {{c1::right (dextro)}}. This is also known as a "{{c2::D-loop}}"
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Published 09/20/2023 With an L-loop, the {{c1::LV}} is on the {{c2::right side}} of the circulation
Published 09/20/2023 The {{c1::endocardial cushions}} end up forming the {{c2::tricuspid and mitral valves}}, which help completing {{c3::septation}}
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Published 09/20/2023 Abnormal blood flow between left and right heart structures is known as a {{c1::shunt}}
Published 09/20/2023 In an atrial septal defect, the blood sometimes flows from the {{c1::left}} atrium to the {{c1::right}} atrium
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Published 09/20/2023 Physiological Events After Birth:Drive to breathe with cord interruption{{c1::Decreased}} pulmonary vascular resistance{{c2::Increased}} pulmonary blo…
Published 09/20/2023 The atrial septum is closed by these 2 structures:{{c1::septum primum}} and {{c1::septum secundum}}
Published 09/20/2023 The {{c1::interventricular}} septum is closed by these 2 structures: {{c2::muscular}} and {{c2::membranous ventricular septum}}
Published 09/20/2023 These structures appear within the {{c1::atrioventricular canal}} and are responsible for development of the {{c2::mitral}} and {{c2::tricuspid valves…
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