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Notes in
01_Hypersensitivity
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Published
02/10/2024
{{c1::Hypersensitivity}} involves an {{c2::over-response to harmless antigens that result in harm to the body}}
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02/10/2024
Type {{c1::I}} Hypersensitivity Reaction involves {{c2::the classical allergy mediated by inappropriate amounts of IgE produced in reaction to harmles…
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02/10/2024
{{c1::Allergens}} are {{c2::antigens that produce allergic reactions (e.g. peanuts, pollen, house dust mite, B-lactam for penicillin)}}
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02/10/2024
Atopic Conditions due to IgE Mediated Allergy {{c1::Food or drug allergy}} {{c1::Asthma}} {{c1::Allergic rhinitis}} {{c1::Hayfever}} {{c1::Eczema}} {{…
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02/10/2024
{{c1::Sensitisation}} in Hypersensitivity is the term used to describe {{c2::the initial event that lead to the specific IgE being developed for that …
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02/10/2024
Symptoms of Allergy {{c1::Itch}} {{c1::Flushing}} {{c1::Rash}} {{c1::Angioedema}} {{c1::Wheeze}}{{c1::Rhinitis}}
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02/10/2024
Describe the Allergic Response {{c1::On re-exposure to the allergen, it binds to the IgE and causes mast cell degranulation, releasing cytokines inclu…
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02/10/2024
Type {{c1::II}} Hypersensitivity Reaction involves the {{c2::production of IgG and IgM antibodies that bind to antigen cells or tissues leading to dam…
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02/10/2024
Examples of Type {{c2::II}} Hypersensitivity Reaction{{c1::Blood Transfusion Reaction}}{{c1::Haemolytic Disease of the Newborn}}{{c1::Goodpasture’s Sy…
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02/10/2024
Type {{c1::III}} Hypersensitivity Reaction involves the {{c2::production of IgG antibody-antigen complexes being deposited in tissues, where they acti…
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02/10/2024
Examples of Type {{c2::III}} Hypersensitivity Reaction{{c1::Rheumatoid Arthritis}}{{c1::Farmers Lung}}
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02/10/2024
Type {{c1::IV}} Hypersensitivity Reaction involves {{c2::a delayed reaction (24-72 hrs) caused by T helper cells travelling to the site of antigens, r…
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02/10/2024
Examples of Type {{c2::IV}} Hypersensitivity Reaction{{c1::Rheumatoid Arthritis}}{{c1::Poison Ivy}}{{c1::Contact dermatitis (Nickel and Gold)}}{{c1::M…
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02/10/2024
Investigation of Type I Hypersensitivity Reaction is via {{c1::Skin-prick testing}}
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02/10/2024
Investigation of Type IV Hypersensitivity Reaction is via {{c1::Patch test for contact dermatitis}}
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02/10/2024
Treatment of Type {{c2::I}} Hypersensitivity Reaction{{c1::Prevention and Desensitisation (Allergen Immunotherapy)}}{{c1::B2-adrenergic agon…
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02/10/2024
Treatment of Type {{c2::IV}} Hypersensitivity Reaction {{c1::Prevention by avoiding antigens}} {{c1::Anti-inflammatory drugs NSAID Corticosteroids TN…
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