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OG9.2 Amenorrhoea
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Published
10/04/2024
{{c1::Primary Amenorrhoea}}: {{c2::absence of onset of menses by age 13 in absence of development of secondary sexual characteristics}} OR {{c2::by ag…
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{{c1::Secondary Amenorrhea}}: {{c2::cessation of previously regular menstruation for 3 months or more}}OR{{c2::cessation of previously irregular …
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First step to investigating primary amenorrhea → {{c1::pregnancy test }}
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The most common cause of primary amenorrhea is {{c1::gonadal dysgenesis (Turner syndrome)}}
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The second most common cause of primary amenorrhea is {{c1::mullerian agenesis (MRKH syndrome)}}
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The third most common cause of primary amenorrhea is {{c1::constitutional/hypogonadotrophic hypogonadism}}
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The fourth most common cause of primary amenorrhea is {{c1::PCOS}}
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The most common broad cause of secondary amenorrhea is {{c1::ovarian (PCOS)}}
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The second most common broad cause of secondary amenorrhea is {{c1::hypothalamic/hypogonadotrophic hypogonadism}}
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The third most common broad cause of secondary amenorrhea is {{c1::uterine}}
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Post-pill amenorrhea needs to be investigated if it has been {{c1::6 months}} since discontinuing OCPs
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Post-pill amenorrhea needs to be investigated if it has been {{c1::12 months}} since the last injection of depo-provera
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{{c1::4}} menstrual cycles a year is sufficient to protect the endometrium
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Kallman syndrome = {{c1::abnormal GnRH neuron development::pathophysiology}} presents as:primary amenorrhea with {{c1::no 2˚ sex characteristics}}{{c1…
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MRKH syndrome = {{c1::vaginal aplasia with other paramesonephric duct/Mullerian duct abnormalities}}Type 1: variable underdevelopment of {{c1::vagina}…
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broad causes of primary amenorrhea with absent 2˚ sex characteristics{{c1::hypogonadotrophic hypogonadism}}: constitutional, anorexia, exercise, Kallm…
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broad causes of primary amenorrhea with normal 2˚ sex characteristics{{c1::Mullerian agenesis/MRKH syndrome}}{{c1::androgen insensitivity syndrome}}{{…
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broad causes of secondary amenorrhea{{c1::physiologic}}: pregnancy, lactation, menopause, RXs{{c1::hypogonadotrophic hypogonadism}}: stress, anorexia,…
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