Notes in CEP VII (Drugs)

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Published	11/11/2024	In endocrinology, a {{c2::receptor}} is a biomolecule that {{c1::hormones}} bind to for biological effects.
Published	11/11/2024	In pharmacology, drug interactions with receptors are more complex because a drug may have {{c1::multiple targets}}, not just {{c1::one}}.
Published	11/11/2024	The noradrenaline transporter is blocked by {{c1::cocaine}} and serves as a {{c1::drug receptor}}.
Published	11/11/2024	Drugs that {{c2::have multiple targets}} are often referred to as {{c1::"Dirty"}} drugs.
Published	11/11/2024	{{c1::Aspirin}} inhibits both COX1 and COX2 enzymes and is an example of a "{{c2::dirty drug.}}"
Published	11/11/2024	{{c2::Steroid hormones}} act by binding to intracellular {{c1::nuclear}} receptors, but can also activate {{c3::membrane-bound GPCRs}}.
Published	11/11/2024	Receptors are named based on the {{c1::hormone or transmitter}} they interact with, as well as its {{c1::inhibitor}}, such as nicotinic acetylcholine …
Published	11/11/2024	The {{c1::patch-clamp}} technique is a {{c2::single-molecule}} method used to measure {{c2::current and quantify receptor response}}.
Published	11/11/2024	GPCRs interact with various G-protein subunits, with {{c1::Gs}} proteins being {{c2::stimulatory}} and {{c1::GI}} proteins being {{c2::inhib…
Published	11/11/2024	There are 4 kinds of receptor Super-Families: {{c1::Integral ion channels}}, {{c1::Tyrosine kinases}}, {{c1::Steroid receptors}} and {{c1::G-protein c…
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