Notes in Chapter_34:_Spleen

To Subscribe, use this Key

Status	Last Update	Fields
Published	07/07/2024	The splenic vein is {{c1::pos}}terior and {{c1::inf}}erior to the splenic artery
Published	07/07/2024	The {{c1::spleen}} is the largest producer of Ig{{c2::M}} in the body
Published	07/07/2024	The spleen is 85% {{c1::red}} pulp
Published	07/07/2024	The red pulp of the spleen has a(n) {{c1::filter}} function
Published	07/07/2024	The white pulp of the spleen has a(n) {{c1::immunologic}} function
Published	07/07/2024	The red pulp of the spleen removes abnormalities in RBC membranes, a process known as {{c1::pitting}}
Published	07/07/2024	Howell-Jolly bodies are remnants of {{c1::nuclei}} in RBCs
Published	07/07/2024	Heinz bodies are remnants of {{c1::hemoglobin}} in RBCs
Published	07/07/2024	The red pulp of the spleen removes less deformable RBCs, a process known as {{c1::culling}}
Published	07/07/2024	An opsonin produced in the spleen that facilitates phagocytosis is {{c1::tuftsin}}
Published	07/07/2024	A protein produced in the spleen that activates the alternate complement pathway is {{c1::properdin}}
Published	07/07/2024	20% of people have an accessory spleen, which is most commonly found at the {{c1::splenic hilum}}
Published	07/07/2024	Splenectomy is more likely to be performed in {{c1::idiopathic}} thrombocytopenic purpura
Published	07/07/2024	Idiopathic thrombocytopenic purpura (ITP) is caused by anti-{{c1::platelet}} antibodies (IgG)
Published	07/07/2024	If ITP fails to respond to steroids, the next best treatment is {{c1::IVIG (gammaglobulin)}}
Published	07/07/2024	ITP in children usually resolves so {{c1::splenectomy}} should be avoided
Published	07/07/2024	After the splenic artery is ligated, the patient should be given {{c1::platelets}}
Published	07/07/2024	Thrombotic thrombocytopenic purpura (TTP) is caused by a loss of platelet inhibition, typically via inactivation of {{c1::ADAMTS13}}
Published	07/07/2024	The primary treatment for TTP is {{c1::plasmapheresis}}
Published	07/07/2024	Death from TTP is most commonly due to {{c2::intracerebral hemorrhage}} or {{c1::acute renal failure}}
Published	07/07/2024	The most common organism that causes post-splenectomy sepsis syndrome (PSSS) is {{c1::Streptococcus pneumoniae}}
Published	07/07/2024	Post-splenectomy sepsis syndrome (PSSS) occurs most in patients with splenectomy due to {{c2::hemolytic disorders}} or {{c1::malignancy}}
Published	07/07/2024	Splenectomy in children is typically deferred until age {{c2::5}} to allow for full {{c1::immunization}}
Published	07/07/2024	Vaccines to encapsulated organisms are typically given {{c1::14}} days {{c2::before::before or after}} {{c3::elective}} splenectomy
Published	07/07/2024	Vaccines to encapsulated organisms are typically given {{c1::14}} days {{c2::after::before or after}} {{c3::emergent}} s…
Published	07/07/2024	Definition of hypersplenism{{c1:::)}}
Published	07/07/2024	The most common congenital hemolytic anemia requiring splenectomy is {{c1::hereditary spherocytosis}}
Published	07/07/2024	The treatment for hereditary spherocytosis is splenectomy and {{c1::cholecystectomy}}
Published	07/07/2024	A disease with a similar pathology to hereditary spherocytosis but is less common is {{c1::hereditary elliptocytosis}}
Published	07/07/2024	The most common congenital hemolytic anemia NOT involving a membrane protein defect that requires splenectomy is {{c1::pyruvate kinase defic…
Published	07/07/2024	Is splenectomy typically required for G6PD deficiency?{{c1::No}}
Published	07/07/2024	Warm-antibody type immune hemolytic anemia is {{c1::more}} common than cold-antibody type
Published	07/07/2024	Is splenectomy indicated for sickle cell disease?{{c1::No}}
Published	07/07/2024	Is splenectomy indicated for beta thalassemia major?{{c1::Yes (if splenomegaly)}}
Published	07/07/2024	Most patients with beta thalassemia major die in their teens secondary to {{c1::hemosiderosis}}
Published	07/07/2024	1 area or 2 contiguous areas on the same side of the diaphragm is Hodgkin's disease stage {{c1::1}}
Published	07/07/2024	2 non-contiguous areas on the same side of the diaphragm is Hodgkin's disease stage {{c1::2}}
Published	07/07/2024	Disease involving both sides of the diaphgram is Hodgkin's disease stage {{c1::3}}
Published	07/07/2024	Disease with liver, bone, lung, or any non-lymphoid tissue involvement is Hodgkin's disease stage {{c1::4}}
Published	07/07/2024	The workup for lymphoma involves:1) {{c1::core needle}} biopsy of lymph node2) {{c2::bone marrow}} biopsy3) {{c3::gallium MRI/PET scan}} of liver and …
Published	07/07/2024	The most common cause of chylous ascites is {{c1::lymphoma}}
Published	07/07/2024	Does Hodgkin's or non-Hodgkin's lymphoma have a better prognosis?{{c1::Hodgkin's}}
Published	07/07/2024	Does hairy cell leukemia require splenectomy?{{c1::Rarely}}
Published	07/07/2024	Spleen tissue breaking off the main organ and implanting at another site is known as {{c1::splenosis}}
Published	07/07/2024	The most common spleen tumor is {{c1::hemangioma}}
Published	07/07/2024	The most common malignant spleen tumor is {{c1::non-Hodgkin's lymphoma}}
Published	07/07/2024	The most common cause of splenomegaly is {{c1::non-Hodgkin's lymphoma}}
Published	07/07/2024	The most common malignant non-blood cell splenic tumor is {{c1::angiosarcoma}}
Published	07/07/2024	Splenic cysts are treated with surgery if they are symptomatic or greater than {{c1::10}} cm in size
Published	07/07/2024	Sarcoidosis of the spleen causes anemia and thrombocytopenia and is treated with {{c1::splenectomy}} if symptomatic
Published	07/07/2024	The treatment for Felty's syndrome is {{c1::methotrexate}}
Published	07/07/2024	Splenic abscesses are most commonly caused by Streptococcus species and are treated with {{c1::splenectomy}}
Published	07/07/2024	Echinococcus usually causes cysts in the liver, but can also cause cysts in the {{c1::spleen}}
Published	07/07/2024	Dermoid cysts of the spleen are treated with {{c1::splenectomy}}
Published	07/07/2024	Pancreatitis occurs {{c1::before}} splenic vein/artery thrombosis(before or after)
Published	07/07/2024	Post-splenectomy changes:RBCs: {{c1::increase}}WBCs: {{c1::increase}}Platelets: {{c1::increase}}(increase or decrease)
Published	07/07/2024	The treatment for platelets greater than 1,000,000 after splenectomy is {{c1::aspirin}}
Published	07/07/2024	Indications for surgical treatment of splenic artery aneurysm is when it is larger than {{c1::2}} cm in diameter
Published	07/07/2024	Abnormal basophilic granules of iron found within RBCs are known as {{c1::Pappenheimer bodies}}
Published	07/07/2024	{{c2::Splenic vein thrombosis}} without fundal variceal bleeding is treating with {{c1::heparin}}
Published	07/07/2024	Overwhelming Post Splenectomy Infections (OPSI) are more common in patients with underlying {{c1::hematologic}} diseases
Status	Last Update	Fields