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Notes in
02. Drug Absorption
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Published
10/21/2024
Driving force for {{c1::Passive Diffusion}} of a drug include:→ {{c1::Concentration gradient }} across a membrane separating two body compartments→ Mo…
Published
10/21/2024
{{c1:: Passive Diffusion}}● Does not involve a {{c1::carrier}}● {{c1::Not saturable}}● Shows {{c1::low}} structural specificity● Vast majority of drug…
Published
10/21/2024
{{c1::Facilitated Diffusion}}● Requires {{c1::drug transporter}}● Involves {{c1::carrier}} proteins that facilitate the passage of large molecules→ Ca…
Published
10/21/2024
This pertains to the pH at which a drug is 50% protonated and 50% non-protonated
Published
10/21/2024
The {{c1::smaller}} the value of pKa, the {{c1::stronger}} the acid
Published
10/21/2024
Give the characteristics of weak bases:Ionization: {{c1::Ionized}} Polarity when protonated: {{c1::More polar when protonated}} Solubility when proton…
Published
10/21/2024
Give the characteristics of weak acids:Ionization: {{c1::Non-ionized}} Polarity when protonated: {{c1::Less polar when protonated}} Solubility when pr…
Published
10/21/2024
This pertains to the volume of drug in the blood if concentration will remain constant and none of the drug will be bound to the tissues
Published
10/21/2024
Give the formula of Volume of Distribution
Published
10/21/2024
Give the different factors that can affect the distribution
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