Notes in 04 Iron Metabolism, Anemia

To Subscribe, use this Key

Status	Last Update	Fields
Published	11/30/2023	The Fe3+ iron in the plasma is bound to {{c1::transferrin}} for transport in the blood
Published	11/30/2023	{{c1::Hepcidin}} binds to the {{c2::ferroportin}} transporter on intestinal mucosal cells and macrophages, thus {{c3::inhibiting}} iron absorption
Published	11/30/2023	Some of the iron absorbed in the duodenum is taken up by {{c1::hepatocytes}} for storage as {{c2::ferritin}}
Published	09/03/2024	{{c1::Total iron-binding capacity (TIBC)}} is approximately 2x the number of {{c2::transferrin}} molecules in the blood
Published	11/30/2023	{{c1::% saturation}} is a measure of the percent of transferrin molecules that are bound by iron
Published	09/03/2024	Serum {{c1::ferritin}} is a reflection of iron stores in macrophages and the liver
Published	09/03/2024	In general, iron deficiency is usually caused by {{c1::dietary lack}} or {{c2::blood loss}}
Published	09/03/2024	In addition to symptoms of anemia, iron deficiency also presents with {{c1::pica::chewing}} and {{c2::koilonychia (spoon nails)::nails}}
Published	09/03/2024	Iron deficiency anemia is characterized by {{c1::hypo}}-chromic RBCs
Published	09/03/2024	Treatment of iron deficiency anemia involves supplemental {{c1::iron (ferrous sulfate)}}
Published	09/03/2024	{{c1::Anemia of chronic disease}} is an anemia associated with cancer and chronic inflammation
Published	09/03/2024	Chronic inflammatory disease results in {{c1::increased}} hepcidin release from the {{c2::liver}}
Published	09/03/2024	Treatment for anemia of chronic disease involves addressing the {{c1::underlying cause}}
Published	09/03/2024	What histological stain is used to visualize iron? {{c1::Prussian blue}}
Published	11/30/2023	What happens to the iron (from heme) within macrophages that have consumed RBCs?{{c1::It is recycled}}
Published	11/30/2023	{{c2::Iron deficiency}} anemia in males (especially > 50) and postmenopausal females raises suspicion of {{c1::colorectal}} carcinoma
Published	11/30/2023	How do the following laboratory values change in anemia of chronic disease? Serum iron: {{c1::decreased}}TIBC: {{c1::decreased}}% Saturation: {{c1::de…
Published	11/30/2023	What acute phase reactant is upregulated during inflammation to bind and sequester iron to inhibit microbial iron scavenging?{{c1::Ferritin}}
Published	11/30/2023	Anisocytosis = variation in RBC {{c1::size::characteristic}}
Published	11/30/2023	Iron deficiency anemia is most commonly caused by excessive {{c1::bleeding}} in young females
Published	11/30/2023	How do the following laboratory values change in iron deficiency anemia? Serum iron: {{c1::decreased}}TIBC: {{c1::increased}}% Saturation: {{c1::decre…
Published	11/30/2023	What type of anemia is characterized the following laboratory values?MCV: normalSerum iron: lowFerritin: high TIBC: low{{c1::Anemia of chronic disease…
Published	11/30/2023	Celiac disease may cause {{c1::iron deficiency anemia::anemia}} in the early stages* bonus: why?
Published	11/30/2023	The signs and symptoms of iron deficiency anemia occur after {{c1::ferritin}} in the bone marrow is depleted
Published	11/30/2023	Severe {{c1::iron deficiency anemia::type of anemia}} may cause a hyperdynamic state with tachycardia, palpitations, and angi…
Published	11/30/2023	{{c1::Anisocytosis}} is a variation in RBC {{c2::size}}
Published	11/30/2023	{{c1::Poikilocytosis}} is a variation in RBC {{c2::shape}}
Published	11/30/2023	Iron from old RBCs is recycled by {{c1::macrophages}}
Published	11/30/2023	The main risk with IV iron is {{c1::anaphylaxis}}
Published	11/30/2023	What type of anemia is characterized by the following laboratory values?MCV: lowSerum iron: lowFerritin: low{{c1::Iron deficiency anemia}}
Published	11/30/2023	What type of anemia is characterized by the following laboratory values?MCV: lowSerum iron: lowFerritin: high{{c1::Anemia of chronic disease…
Published	11/30/2023	The gold standard test to confirm iron deficiency anemia: {{c1::Bone marrow biopsy stained with Prussian blue (Perl’s stain).}}
Published	11/30/2023	What is the single best non-invasive test to rule in or rule out iron deficiency anemia?
Status	Last Update	Fields