Notes in Cushing’s syndrome

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Published	05/12/2024	Cushing's is all about an increase in what?
Published	05/12/2024	Cushing's syndrome vs. Cushing's disease?
Published	05/12/2024	Describe exogenous vs. endogenous Cushing's?
Published	05/12/2024	Is the majority of Cushing's syndrome exogenous or endogenous cause?
Published	05/12/2024	What is the most common cause of endogenous Cushing's?
Published	05/12/2024	Describe adrenocorticotropic hormone (ACTH)-dependent or ACTH-independent Cushing's syndrome?
Published	05/12/2024	What is adrenocorticotropic hormone (ACTH) and where does it come from?
Published	05/12/2024	What is corticotropin-releasing hormone (CRH) and where does it come from?
Published	05/12/2024	Is most cortisol free or bound? what happens to excess free cortisol?
Published	05/12/2024	Is cortisol higher or lower in the morning?
Published	05/12/2024	high levels of cortisol tell the hypothalamus and pituitary gland to (decrease or increase) their secretion of CRH and ACTH?
Published	05/12/2024	How does excess cortisol affect glucose and insulin levels in the blood?
Published	05/12/2024	What is symptom of Cushing's is related to elevated insulin levels?
Published	05/12/2024	How does excess cortisol affect muscle, bone and skin?
Published	05/12/2024	Most common initial diagnosis of Cushing syndrome?
Published	05/12/2024	Another option for the initial diagnosis of Cushing syndrome?
Published	05/12/2024	How do cortisol levels which increase in times of stress affect gluconeogenesis?
Published	05/12/2024	What is a feature of Cushing syndrome due to cortisol-mediated break down of muscle to produce amino acids for gluconeogenesis.
Published	05/12/2024	What are the clinical manifestations of Cushing syndrome?
Published	05/12/2024	What is the most common cause of Cushing syndrome?
Published	05/12/2024	What test is used diagnostically to identify the underlying cause of non-iatrogenic Cushing syndrome.
Published	05/12/2024	A 24-hour urine free cortisol is elevated, a late night salivary cortisol is elevated, and/or there is an inadequate suppression on 1 mg overnight dex…
Published	05/12/2024	What type of lung tumors can cause excessive ACTH production and Cushing syndrome?
Published	05/12/2024	How will cortisol levels respond to a dexamethasone suppression test in patients with Cushing syndrome caused by cortisol-producing adrenal tumor?
Published	05/12/2024	What is a drug used in Cushing syndrome that inhibits 11-beta-hydroxylase, thereby inhibiting glucocorticoid synthesis?
Published	05/12/2024	What are the causes of ectopic ACTH secretion?
Published	05/12/2024	What is the usual presentation of ectopic ACTH production?
Published	05/12/2024	Does Cushing disease present with hypokalemia or hyperkalemia?
Published	05/12/2024	Does primary adrenocortical insufficiency from a pituitary tumor present with hypokalemia or hyperkalemia?
Published	05/12/2024	What 2 screening tests are used to confirm hypercortisolism?
Published	05/12/2024	What is the radiographic test of choice for identifying suspected pituitary adenomas?
Published	05/12/2024	What is the treatment for Cushing disease?
Published	05/12/2024	What is the treatment for Cushing syndrome secondary to adrenal adenomas and carcinomas?
Published	05/12/2024	What is the radiographic test of choice for identifying suspected ectopic ACTH hypercortisolism (aka small cell lung cancer, etc.)?
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