Notes in David Beatty + Ivan Nettar

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Published 05/25/2025 Q: When BLANK is bound to myosin, the myosin head is in a cocked state
Published 05/25/2025 Q: During crossbridge formation, Ca2+ binds BLANK to displace tropomyosin from the myosin binding site
Published 05/25/2025 Q: What is the name of the microscopic barrier between sarcomeres, to which actin filaments are attached to
Published 05/25/2025 Q: What is the function of Dystrophin?
Published 05/25/2025 Q: What Neurotransmitter is released at the NMJ in Parasympathetic and autonomic neurons?
Published 05/24/2025 Q: What condition is characterized by autoantibodies targeting Ca2+ channels that prevent the release of ACh from the presynaptic terminal
Published 05/25/2025 Q: List 4 clinical features of LEMS?
Published 05/24/2025 Q: What substance cleaves SNARE proteins, thus preventing the release of ACh from the presynaptic terminal?
Published 05/25/2025 Q: What condition is characterized by antibodies that act against AChR and MuSK?
Published 05/25/2025 Q: What is typically the first symptom that appears in generalized Myasthenia Gravis?
Published 05/24/2025 Q: What enzyme has elevated serum levels associated with muscle damage?
Published 05/24/2025 Q: What type of muscle weakness do myopathies typically present with?
Published 05/24/2025 Q: TRUE/FALSE - 67% of people with Duchenne Muscular dystrophy are assigned Female at birth
Published 05/25/2025 Q: Why is the dystrophin gene more susceptible to spontaneous mutation
Published 05/24/2025 Q: Why do patient’s with Duchenne Muscular Dystrophy seem to have increased muscle bulk - especially at the calves?
Published 05/25/2025 Q: What condition has reduced amounts of dystrophin protein
Published 05/25/2025 Q: Duchenne Muscular dystrophy can cause cardiac complications such as BLANK
Published 05/25/2025 Q: What type of gait is often associated with Duchenne Muscular dystrophy?
Published 05/25/2025 Q: What two enzymes have typically elevated serum levels in Duchenne Muscular dystrophy?
Published 05/24/2025 Q: Name two pharmacological therapies used to treat Duchenne Muscular dystrophy
Published 05/24/2025 Q: The most common autoantibodies implicated in Myasthenia Gravis. BONUS: Name two other antibodies
Published 05/25/2025 Q: What is a condition often associated with Myasthenia Gravis?
Published 05/24/2025 : Why are thymomas often associated with Myasthenia Gravis
Published 05/24/2025 Q: Name four muscle groups typically affected in generalized Myasthenia Gravis and their corresponding impairments (at least 1 per category)
Published 05/24/2025 Q: Is limb and ocular weakness symmetrical or asymmetrical in Myasthenia Gravis?
Published 05/24/2025 Q: What is first tested in diagnosis of Myasthenia Gravis
Published 05/24/2025 Q: What imaging modality is used to diagnose Myasthenia Gravis and why is it relevant?
Published 05/25/2025 Q: What is the first line pharmacological treatment for Myasthenia Gravis?
Published 05/25/2025 Q: List 7 symptoms of a Myasthenic Crisis
Published 05/24/2025 Q: List 5 ways to differentiate between cholinergic and Myasthenic crisis 
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