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06ConnectiveTissue
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four-florida-hotel-river-friend-uranus
Status
Last Update
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Published
07/30/2024
most abundant and most widely distributed type of tissue
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07/30/2024
Connective tissue is important because it contains {{c1::cells}} and an {{c1::extracellular matrix}} [basic components]
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07/30/2024
What is the extracellular material made out of?
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07/30/2024
Structural properties of connective tissue cells (w/ corresponding substance which lend these proeprties)
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07/30/2024
{{c3::Connective}} tissue arises from the {{c1::primitive mesenchymal cell}} / {{c2::multipotential embryonic mesenchyme cells}}
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Mesenchymal definition
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Multipotential definition
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07/30/2024
Connective tissues have high or low density?
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07/30/2024
How do the components of connective tissue look like under LM?
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07/30/2024
Where to most of the components of connective tissue proper belong to
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07/30/2024
Main protein of collagenous tissue
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07/30/2024
Collagen is the name for what
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07/30/2024
Property of collagenous tissue
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What type of tissue has collagen as its main fiber type
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How many types of collagen are there
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Appearance of collagen under the microscope (Masson trichrome stain)
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Appearance of collagen under the microscope (H&E)
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Appearance of collagen under the microscope (EM)
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Type 1 collagenous tissue
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2 types of Type 1 Collagenous tissue: Main Structural Collagen
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{{c4::Loose Areolar}} Connective Tissue{{c1::Loose and widely distributed::Distribution}}Can be found in the {{c2::superficial and deep fascia}}O…
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07/30/2024
2 Types of Dense Connective Tissue
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{{c2::Dense}} Connective TissueCollagen fibers are {{c1::closely packed}}
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{{c3::Dense Irregular}} Connective TissueCollagen fibers are {{c1::randomly oriented::orientation}}Found in the {{c2::dermis}}, {{c2::capsule of …
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07/30/2024
{{c4::Dense Regular}} Connective TissueCollagen fibers are {{c1::organized::organization}}, oriented in {{c1::one direction::direction}}, and&nbs…
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Type 2 collagenous tissue
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Type 2 collagenous tissue: Hyaline Cartilage Matrix is found in
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Type {{c5::2}} Collagenous Tissue: {{c5::Hyaline Cartilage Matrix}}{{c1::Glass-like, translucent cartilage::appearance}} found on …
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Most prevalent type of cartilage
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Type 3 collagenous tissue
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Type {{c1::3}} Collagenous Tissue: {{c1::Reticular Fiber}}Composed of type {{c1::III collagen}} secreted by {{c1::reticular}} cell…
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Type 4 collagenous tissue
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Type {{c6::4}} Collagenous Tissue: {{c6::Basement Membrane}}Found in the {{c1::basement membrane }}Forms a {{c1::sheet-l…
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Type 7 Collagenous Tissue
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Type {{c3::7}} Collagenous Tissue: {{c3::Anchoring Fibrils}}Found in {{c1::anchoring fibrils}} for the {{c1::basement membran…
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2nd component of connective tissue proper
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07/30/2024
Major protein in elastic tissue
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{{c8::ELASTIN}}Another type of protein fiber found in the extracellular matrix of connective tissueArranged as {{c1::fibers}} or {{c1::disco…
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2rd component of connective tissue proper
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{{c6::Ground Substance}}{{c1::amorphous::appearance}}; {{c1::semi-solid gel::appearance}}Contents:{{c2::Water}} and {{c2::Salts (sodium…
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07/30/2024
Complex carbohydrates of the Proteoglycans / Glycosaminoglycans (GAG) in Ground Susbtance:{{c1::Hyaluronic acid}}{{c2::Chondroitin-4-sulphate,&nb…
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4th component of connective tissue proper
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4 components of connective tissue proper
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07/30/2024
Precursor cell
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Function of precursor cells
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principal, most abundant cells of connective tissue
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07/30/2024
Function of {{c3::Fibroblasts}}synthesizes {{c1::proteins}}, {{c1::glycoproteins}}, and {{c1::glycosaminoglycans}}produces {{c2::precur…
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07/30/2024
Features of Fibroblasts
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Function of {{c2::Macrophages}}:{{c1::phagocytosis}} of particulate material (ingest bacteria, dead and dying cells)part of {{c1::immune def…
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07/30/2024
Features of {{c2::Macrophages}}:{{c1::irregular nucleus}}, {{c1::lysosomes}}, etc.When {{c1::active::active/inactive}}, they exhibit {{c1::pseudo…
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07/30/2024
{{c2::Tissue-fixed Macrophages / Histiocytes}}{{c1::histiocytes}}{{c1::Kupffer cells}}{{c1::alveolar macrophages}}{{c1::microglia}}
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07/30/2024
Function of {{c3::adipocytes}}:specialized for {{c1::fat storage}} in the form of {{c1::triglycerides (TG)}}a source of {{c2::ener…
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07/30/2024
Features of {{c2::Adipocytes}}:{{c1::signet ring}}-shaped{{c1::peripheral}} nuclei“{{c1::empty}}” cytoplasm; {{c1::H&E}} stain {{c1::dis…
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07/30/2024
infrequent cells; cells usually only seen in areas of inflammation
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07/30/2024
{{c2::Plasma}} Cells{{c1::hematopoietic}} stem cell-derivedFunction: produces {{c1::antibodies}}Features: {{c1::cartwheel}} a…
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07/30/2024
Mast cells are abundant in the following areas:{{c1::skin}}{{c1::GI lining}}{{c1::serosal lining}} of {{c1::peritoneal}} and {{c1::pleural}}…
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07/30/2024
Function of {{c4::Mast}} Cells: involved in {{c1::anaphylactic reactions }}have {{c2::granules}} containing {{c3::heparin}} a…
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Features of {{c3::Mast}} Cells: {{c1::Toluidine blue}} stain - granules become {{c2::deep purple}} (L/M)
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Collagenous Tissue Types:Type {{c1::1: Main Structural}}Type {{c1::2: Hyaline Cartilage Matrix}}Type {{c1::3: Reticular Fiber}}Type {{c1::4: Basement …
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semi-rigid form of connective tissue
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Are all forms of cartilage vascular or avascular?
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Ground substance of {{c3::Cartilage}}: {{c1::chondromucoid}} rich in {{c2::chondroitin sulfate}}Matrix of {{c3::cartilage}}: with {{c4::coll…
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dense fibrous connective tissue of cartilage
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Which forms of cartilage do not have perichondrium?
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Three major classifications of Cartilage:
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most common type of cartilage
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Matrix of hylaine cartilage: {{c1::type II collagen}} and {{c2::chondroitin sulfate}}
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3 SUBTYPES OF HYALINE CARTILAGE
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Hyaline cartilage found in respiratory system
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07/30/2024
Hyaline cartilage found between articulating surfaces (joints)
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Hyaline cartilage found in embryonic skeletal system
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Where is fetal hyaline cartilage not found in the the embryonic skeletal system?
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Hyaline cartilage with big chondroblasts in inner chondrogenic layer
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Hyaline cartilage with bigger chondrocytes; more cellular
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Hyaline cartilage with young chondroblasts (numerous, small, irregularly arranged)
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Contents of matrix of {{c1::adult}} and {{c1::articular}} hyaline cartilage:{{c2::chondrocytes}} within {{c2::lacunae (space)}}{{c2::central ovoi…
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07/30/2024
Which types of hyaline cartilage have cell families
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Hyaline cartilage for structural support
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Hyaline cartilage for low-friction surfaces and shock absorbers in weight-bearing joints
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Hyaline cartilage for framework for endochondral ossification (Skeletal model for bones); early stage in the development of ALL types of cartilage
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Where is elastic cartilage found
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Does elastic cartilage have perichondrium?
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Does elastic cartilage have cell families?
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Distinguishing feature of elastic cartilage
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modification of adult hyaline cartilage
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Where is fibrocartilage located?
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transition between dense fibrous connective tissue and hyaline cartilage
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How are chondrocytes in fibrocartilage arranged
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How are collagen fibers arranged in fibrocartilage
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Rigid form of connective tissue with cell, fibers, and ground substance / matrix
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Ground substance of {{c1::bone / Osseous Tissue}}: {{c2::calcified (becomes hard and brittle)}}
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07/30/2024
Bone calcified matrix made up of some organic elements:{{c1::collagen}}{{c1::protein polysaccharide}}{{c1::chondroitin sulfate}}and mostly inorganic e…
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The calcified matrix of bone has more organic or inorganic elements?
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Forms of bone
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in cartilage: {{c1::chondrocytes}} are in the lacunain bone: {{c1::osteocytes}} are in the lacuna
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07/30/2024
also known as cortical bone
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07/30/2024
a denser material used to create much of the hard structure of the skeleton
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formed from a number of osteons
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Compact bone forms the {{c1::cortex, or hard outer shell}} of most bones in the body
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serve a function in calcium storage and release to the body when needed
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Simplest unit of compact bone
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Components of Osteon / Haversian system
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07/30/2024
Consists of parallel bony columns made up of concentric bony layers surrounding the haversian canal
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perpendicular to the haversian canal
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Both the Haversian canal and Volkman’s channel / canal
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forms of communication between osteocytes; no blood vessels
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also known as cancellous bone or trabecular bone
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07/30/2024
makes up 20% of the human skeleton
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07/30/2024
a very porous type of bone
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07/30/2024
softer, weaker, and more flexible than compact bone
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07/30/2024
highly vascularized and contains red bone marrow
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07/30/2024
Simplest unit of Spongy bone
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07/30/2024
characterized by a lattice-like, eosinophilic matrix network called trabeculae (instead of osteons; simplest unit)
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Staining nature of matrix network of spongy bone
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07/30/2024
Where is spongy bone found
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07/30/2024
stores 99% of the body’s calcium and 85% of the phosphorus
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07/30/2024
Site of erythropoiesis RBC produced at a rate of about 2million/sec
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07/30/2024
Adds strength and flexibility to bones
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Where do the trabeculae of spongy bone form?
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07/30/2024
Mineral storagestores 99% of the body’s calcium and 85% of the phosphorus
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Does spongy bone have a a haversian system?
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Trabeculae of spongy bone are lined by
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thick-walled hollow cylinder w/ a central medullary cavity containing the yellow bone marrow
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The inside of the shaft/Diaphysis of the bone is lined with
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contains compact bone
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ends of long bone
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made up of spongy bone
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Part of the bone covered by a thin cortex of compact bone
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a layer of vascular and neural CT w/ osteogenic potential
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07/30/2024
outer fibrous covering of the bone (except at joints)
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07/30/2024
a thin cellular layer w/ osteogenic properties
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07/30/2024
lines the medullary / marrow cavity
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central cavity of bone shafts that contains yellow bone marrow
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separates the epiphysis from the diaphysis
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a transitional region connecting the epiphyseal plate to the diaphysis
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give rise to different types of blood cells: myeloid and lymphoid cells
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More abundant Hematopoietic stem cells
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For development, homeostasis, tissue repair
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Less abundant Hematopoietic stem cells
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For adaptive and cell-mediated immunity
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basophils are examples of?
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Neutrophils are examples of?
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Eosinophils are examples of?
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Macrophages are examples of?
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Erythrocytes are examples of?
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Mast cells are examples of?
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Myeloblasts are examples of?
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Megakaryocytes are examples of?
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07/30/2024
T lymphocytes (cell-mediated immunity) are examples of?
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B lymphocytes (adaptive immunity) are examples of?
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Natural killer cells (cytotoxic cells that cause death of infected cells) are examples of?
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The spongy tissue inside the bones
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Bone Marrow contains
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2 types of bone marrow
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Bone marrow that is red in color because of abundance of blood cells; very few fat cells
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07/30/2024
Bone marrow that is yellow in color because of abundance of fat cells
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Bone marrow w/ active hematopoietic tissue; produces RBC, WBC, platelets
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replaced by yellow bone marrow during aging
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Bone marrow not active in hematopoiesis
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converted into red bone marrow if needed in hematopoiesis (e.g. in case of severe blood loss)
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found in diaphysis of long bones (medullary cavity)
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When is red bone marrow found in all marrow cavities
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Where is red bone marrow found in older individuals
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Quiet macrophages are abundant in
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07/30/2024
Antibodies of Mast Cells
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07/30/2024
Which can still grow: epiphyseal line or plate?
Status
Last Update
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