Notes in Pharm 241

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Published 01/29/2024 Exclusions for Headache (cannot be solved with self-care)• {{c1::Severe headache (unlike any other headache, intolerable)}}• Headache lasting for more…
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Published 01/29/2024 what is best for anti-inflammatory?
Published 01/29/2024 What can cause liver toxicity?
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Published 01/29/2024 Acetaminophen oral suspension is available OTC in concentrations of?
Published 01/29/2024 Ibuprofen oral suspension (motrin) is available OTC in concentration of?
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Published 01/29/2024 What is Voltaren?
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Published 01/29/2024 CLASSIFICATION – Allergic RhinitisBased on time and duration of symptoms1. {{c1::Intermittent}}: symptoms occur {{c3::≤4 days per week OR ≤4 weeks}}- …
Published 01/29/2024 Allergic Rhinitis vs. ColdAllergic Rhinitis• Sneezing• Congestion (runny or stuffy nose)• Coughing•{{c1:: Thin, clear mucus• Itchy,}} red, watery…
Published 01/29/2024 EXCLUSIONS FOR SELF-CARE – Allergic Rhinitis• Children {{c1::<12 years}}• {{c1::Pregnant or lactating}} women• Symptoms of {{c2…
Published 01/29/2024 TREATMENT GOALS and GENERAL APPROACHTreatment Goals• Reduce frequency of symptoms• Improve daily functions and quality of life• Reduce or prevent adve…
Published 01/29/2024 **PHARMACOTHERAPY – Allergic Rhinitis• {{c1::Intranasal corticosteroids (INCS):}} {{c2::often first line for AR (esp. in severe AR);}}4 OTC agents• {{…
Published 01/29/2024 **Intranasal Corticosteroids• {{c1::Most effective in treatment of AR}}• Inhibit different cell types and mediators, stopping the allergic cascad…
Published 01/29/2024 **Intranasal Corticosteroids• {{c1::Intranasal spray, not oral inhalation (e.g. Flonase-OTC, not Flovent-oral inhaler-not OTC)}}Adverse Effects:•…
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Published 01/29/2024 **Antihistamines• MoA: {{c1::compete with histamine at central and peripheral H1 receptors, preventing the histamine-receptor interaction, i…
Published 01/29/2024 **AntihistaminesFirst Generation• {{c1::Lipophilic, easily crosses blood-brain barrier (BBB) - sedating}}• Quick onset, shorter duration• High anticho…
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Published 01/29/2024 Mast Cell StabilizerCromolyn sodium• Blocks {{c2::calcium influx}} into mast cells, preventing mediator release• May take {{c2::3-7 days}} for improve…
Published 01/29/2024 **Comparison of Pharmacotherapy• Intranasal corticosteroids are {{c2::most effective, considered first line, esp. withnasal symptoms; needs routine ma…
Published 01/29/2024 **CLINICAL PRESENTATION – Cold• Symptoms begin {{c1::1 to 3}} days after infection1. {{c1::Sore throat:}} first symptom to occur2. {{c1…
Published 01/29/2024 EXCLUSIONS FOR SELF-CARE – Cold• {{c1::Fever >100.4°F (38°C oral)}}• {{c1::Chest pain}}• {{c1::Shortness of breath}}• Worsening or a…
Published 01/29/2024 TREATMENT GOALS and GENERAL APPROACHTreatment Goals• Reduce and relieve symptoms (sore throat, congestion, cough, low grade fever)• Prevent transmissi…
Published 01/29/2024 **PHARMACOTHERAPY – Cold• {{c2::Decongestants}}: congestion symptoms; limit use to {{c1::3 – 7 days to avoid toxicity}}• {{c2::Local anesthetics:}} so…
Published 01/29/2024 **Decongestants• Sympathomimetic oral decongestants: indicated for {{c1::temporary relief of nasal congestion and cough associated with post-nasal dri…
Published 01/29/2024 *Decongestants• Do not use decongestants in children {{c1::younger than 4 years of age.}}• Adverse effects: {{c1::cardiac stimulation}}&nbsp…
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Published 01/29/2024 Which cold medicine does not contain decongestant (recommend for HTN)?
Published 01/29/2024 **Local Anesthetics• Indicated for {{c1::temporary relief of sore throats}}• {{c2::Benzocaine, menthol, dyclonine}}• May be used {{c2::Q2-4H}}• Avoid …
Published 01/29/2024 Pharmacotherapy in Special PopulationPregnant women: {{c1::non-pharmacological therapy}} is first line• Avoid {{c1::systemic decongesta…
Published 01/29/2024 CLINICAL PRESENTATION – CoughProductive• Wet cough to {{c1::expel secretions from lower respiratory tract to help in ventilation and ability for …
Published 01/29/2024 EXCLUSIONS FOR SELF-CARE – Cough• Difficulty in {{c1::breathing or shortness of breath}}• {{c1::Hemoptysis}} (coughing up blood)• {{c1::Weight lo…
Published 01/29/2024 TREATMENT GOALS and GENERAL APPROACHTreatment Goals• Reduce number and severity of cough episodes• Prevent complications of cough• Treat underlying ca…
Published 01/29/2024 **PHARMACOTHERAPY – CoughAntitussives: cough suppressants, used as needed within recommended daily dose; drug of choice for nonproductive cough- {{c1:…
Published 01/29/2024 Antitussives{{c1::Dextromethorphan - Products with labeling “Cough” or “DM”}}• {{c3::Non-opioid, no analgesic effect}}• Suppression of nonproduct…
Published 01/29/2024 AntitussivesCodeine• Suppression of nonproductive cough caused by respiratory tract irritation• Schedule {{c1::V}} narcotic, OTC in {{c…
Published 01/29/2024 {{c1::Expectorants}}{{c2::Guaifenesin}} –Products with labeling {{c2::“Chest Congestion”}} or {{c2::“Loosens Mucus”}}• Symptomatic…
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