Notes in OG8.4b Malignant Ovarian Masses

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Published	10/04/2024	Epithelial ovarian carcinomas:- {{c1::Serous cystadenocarcinoma }}- {{c1::Mucinous cystadenocarcinoma }}- {{c1::Clear cell ca…
Published	10/04/2024	Sex cord/stromal ovarian cancers:- {{c1::Granulosa cell tumours (secrete estrogen)}}- {{c1::Sertoli-leydig cell tumour (secrete testosterone…
Published	10/04/2024	Germ cell ovarian cancers:- {{c1::Dysgerminoma (secrete LDH)}}- {{c1::Immature malignant teratoma}}- {{c1::Endodermal sinus/yolk sac tu…
Published	10/04/2024	Women who have been pregnant have a {{c1::50}}% ↓ risk of developing ovarian cancer compared to nulliparous women
Published	10/04/2024	OCP use decreases the risk of ovarian cancer by {{c1::40 }}%
Published	10/04/2024	Genetic syndromes that are associated with ovarian cancers include {{c1::BRCA1}}, {{c1::BRCA 2 }} and {{c1::HNPCC }}
Published	10/04/2024	Imaging used in investigation of ovarian carcinoma:- {{c1::Pelvic ultrasound }}- {{c1::Abdominal ultrasound }}- {{c…
Published	10/04/2024	Blood tests used when investigating ovarian carcinoma:- {{c1::FBC}}- {{c1::LFTs}}- {{c1::U&E}}- {{c1::CA 125}}- {{c1::CA 19-9}}- {{…
Published	10/04/2024	FIGO Stage 1 ovarian cancer = {{c1::Growth limited to 1 or both ovaries::definition}}Has a {{c1::80-90::range}}% 5-year survival rate
Published	10/04/2024	FIGO Stage 2 ovarian cancer = {{c1::spread to pelvic structures::definition}}Has a {{c1::67-70::range}}% 5-year survival rate
Published	10/04/2024	FIGO Stage 3 ovarian cancer = {{c1::peritoneal implants outside the pelvis and/or positive retroperitoneal lymph nodes::definition}}Has a {{c1::29-59:…
Published	10/04/2024	FIGO Stage 4 ovarian cancer = {{c1::Distant metastases to liver +/- lung and pleural effusion::definition}}Has a {{c1::17::range}}% 5-year survival ra…
Published	10/04/2024	Aim of primary surgery in ovarian cancer:- {{c1::Confirm diagnosis }}- {{c1::Stage }}- {{c1::Remove all cancer or optima…
Published	10/04/2024	The current recommendation for debulking surgery in ovarian cancer is to aim for minimum disease, leaving deposits with a maximum individual diameter …
Published	10/04/2024	Delayed primary debulking surgery in ovarian cancer is performed once they have completed three cycles of {{c1::neoadjuvant chemotherapy}}
Published	10/04/2024	Standard chemotherapy for ovarian cancer is {{c1::taxol (paclitaxel)}} and {{c1::platinum (carboplatin)}} based chemotherapy
Published	10/04/2024	In patients that can't tolerate paclitaxel and platinum, give {{c1::carboplatin}} alone
Published	10/04/2024	T/F Radiotherapy is used often in the treatment of ovarian carcinoma.{{c1::F}}
Published	10/04/2024	Current practice for follow up of ovarian cancer if in remission and asymptomatic → follow up every {{c1::3 months}} in the first {{c1::two years…
Published	10/04/2024	Recurrent ovarian cancer is {{c1::incurable::curable/incurable}}
Published	10/04/2024	Lifetime risk of ovarian cancer is 1 in {{c1::70-80::range}} women
Published	10/04/2024	Protective factors for ovarian cancer50% risk reduction if {{c1::previously been pregnant}}{{c1::breastfeeding}}{{c1::hysterectomy}} or {{c1::tubal oc…
Published	10/04/2024	Risk factors for ovarian cancermore common in {{c1::northern Europe and USA::2 geographical areas}}5-10% of cases are {{c1::familial (BRCA1/2, HNPCC}}…
Published	10/04/2024	Types of ovarian cancers90% {{c1::epithelial (cystadenocarcinoma)}} tumors {{c1::germ cell}} tumors{{c1::sex cord}} tumors{{c1::metastatic}}…
Published	10/04/2024	Serous cell cystadenocarcinomas secrete {{c1::CA-125}}Mucinous cell cystadenocarcinomas secrete {{c1::CA-19-9}}
Published	10/04/2024	{{c1::75}}% of ovarian cancer presents as late stage (3 or 4) disease with 5-year survival or {{c1::30-40}}%
Published	10/04/2024	Symptoms of {{c1::ovarian cancer}} includeabdominal discomfroturinary frequency/pressure effects on bladder and rectumabdominal fullnessGI symptomsabn…
Published	10/04/2024	Exam findings in ovarian cancerabdominal distension, irregular wall ({{c1::omental caking}})palpable mass abdominally or during pelvic examascites - {…
Published	10/04/2024	Follow-up after treatment for ovarian cancerevery {{c1::3}} months for {{c1::2}} yearsevery {{c1::6}} months until {{c1::5}} years
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