Notes in OG9.4 Pathophysiology of infertility

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Status	Last Update	Fields
Published	10/04/2024	Definition of infertility: {{c1::Failure  to conceive a clinical pregnancy after 12 months or more of regular unprotected intercourse}}
Published	10/04/2024	Primary infertility → {{c1::Couple has never conceived::Definition }}
Published	10/04/2024	Secondary infertility → {{c1::Couple has had at least 1 previous conception together::Definition }}
Published	10/04/2024	Cumulative pregnancy rate over 2 years is {{c1::90%::%}}
Published	10/04/2024	Most common cause of infertility → {{c1::male factors }}
Published	10/04/2024	Spermatogenesis occurs in the {{c1::seminiferous tubules::anatomic location}}
Published	10/04/2024	Testosterone is produced by {{c1::Leydig cells }}
Published	10/04/2024	FSH stimulates {{c1::spermatogenesis }} in males
Published	10/04/2024	LH stimulates {{c1::testosterone production }} in males
Published	10/04/2024	Congenital causes of primary testicular dysfunction:- {{c1::Klinefelter's syndrome }}- {{c1::Cryptorchidism }}- {{c1::infecti…
Published	10/04/2024	Chemotherapy can cause {{c1::irreversible::reversible/irreversible}} azoospermia
Published	10/04/2024	Anabolic steroids, sulfasalazine and antifungals can cause {{c1::reversible::reversible/irreversible}} azoospermia
Published	10/04/2024	Surgical correction of a varicocoele {{c1::does not::does/does not }} improve sperm count
Published	10/04/2024	FSH promotes {{c1::follicular development }} in the female
Published	10/04/2024	LH allows {{c1::ovulation}} and {{c1::maintenance of the corpus luteum }} in the female
Published	10/04/2024	Genetic cause of hypergondotrophic hypogonadism:- {{c1::Turner syndrome }}
Published	10/04/2024	How does endometriosis cause impaired fertility:- {{c1::Anatomic distortion from pelvic adhesions }}- {{c1::Damage to ovarian tissue by…
Published	10/04/2024	{{c1::20-25}}% of infertility is unexplained
Status	Last Update	Fields