Notes in Lecture 20

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Published 03/09/2024 Define peripheral and central tolerance and discuss theirimportance in regulation of immune response.
Published 03/09/2024 Differentiate between mechanisms of B cell- and T cell-tolerance.
Published 03/09/2024 Discuss how antigens can cause tolerance.
Published 03/09/2024 Explain how maternal immunity prevents successfulvaccination of newborn animals.
Published 03/09/2024 Discuss characteristics and functions of Treg cells.
Published 03/09/2024 Explain how Treg and Th17 cells regulate immune responses.
Published 03/09/2024 What is tolerance?
Published 03/09/2024 Why is it important to regulate the immune system? What happens if it is too high or too low?
Published 03/09/2024 How is developing T cells exposed to self antigens in the thymus?
Published 03/09/2024 What leads to peripheral T-cell Tolerance? pg11
Published 03/09/2024 What is anergy? pg 11
Published 03/09/2024 How is anergy stimulated? pg 11
Published 03/09/2024 What are Tolerogenic Self-Antigens VS Immunogenic Foreign Antigens? pg 18
Published 03/09/2024 What is central B cell tolerance? pg 19
Published 03/09/2024 Why are B-cells more likely to become self reactive than T cells? pg 19
Published 03/09/2024 Why do we vaccinate animals at a few weeks old? pg21
Published 03/09/2024 How do we regulate this T cell response? pg 23
Published 03/09/2024 What is T regs? pg24
Published 03/09/2024 What do T regs express? pg 24
Published 03/09/2024 What is foxp3? pg 24
Published 03/09/2024 What is a Natural Treg cells (nTreg)?
Published 03/09/2024 What is a Induced Treg cells (iTreg)?
Published 03/09/2024 What is the function of the cytokine TGF-B? pg 27
Published 03/09/2024 What is the function of the cytokine IL-10? pg 27
Published 03/09/2024 What is the function of the cytokine IL-35? pg 27
Published 03/09/2024 What cytokines are immunosuppressive mediators? pg 27
Published 03/09/2024 Explain tolerance in Dizygotic twins? How is this different from Monozygotic? 
Published 03/09/2024 What would be expected if there was an absence of Tregs in the body?
Published 03/09/2024 What is unique to expression in terms of Tregs?
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