Notes in Antimicrobials

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Status	Last Update	Fields
Published	09/25/2023	9963c0e0261c4d8cb2f4b3ce7c62ce20-ao-1
Published	09/25/2023	9963c0e0261c4d8cb2f4b3ce7c62ce20-ao-2
Published	09/25/2023	9963c0e0261c4d8cb2f4b3ce7c62ce20-ao-3
Published	09/25/2023	9963c0e0261c4d8cb2f4b3ce7c62ce20-ao-4
Published	09/25/2023	9963c0e0261c4d8cb2f4b3ce7c62ce20-ao-5
Published	09/25/2023	259df9a0e985443d8ae14a28f0e72d1e-ao-1
Published	09/25/2023	259df9a0e985443d8ae14a28f0e72d1e-ao-2
Published	09/25/2023	259df9a0e985443d8ae14a28f0e72d1e-ao-3
Published	09/25/2023	259df9a0e985443d8ae14a28f0e72d1e-ao-4
Published	09/25/2023	259df9a0e985443d8ae14a28f0e72d1e-ao-5
Published	09/25/2023	259df9a0e985443d8ae14a28f0e72d1e-ao-6
Published	09/25/2023	{{c3::sulfomethoxazole}} + {{c3::trimethoprim}} (aka. combination drug {{c4::Bactrim}}) is an anti-metabolite{{c1::beta-lactams}} are inhibitors of ce…
Published	09/25/2023	Bactrim ({{c3::sulfamethozaxole (SMX)}} + {{c2::trimethoprim (TMP)}}) prevents {{c1::folic acid}} synthesis in bacteria → no AA, purine, thymidine syn…
Published	10/05/2023	inhibitors of cell wall synthesis*{{c1::50}}% of all antibiotics used → do not have any effect on human cells because they lack cell wall entirely&nbs…
Published	09/25/2023	Gram staining- crystal {{c1::violet::color}} dye binding to cell wall → gives info on shape and Gram of the bacteria - Staphylococcus aureus are …
Published	09/25/2023	Penicillin *considered the miracle drug- four carbon {{c4::beta-lactam}} ring is unstable... opened up in low pH in stomach - {{c1::Amoxicil…
Published	09/25/2023	eaa91d0270eb436999d3772148cb71d8-ao-1
Published	09/25/2023	eaa91d0270eb436999d3772148cb71d8-ao-2
Published	09/25/2023	eaa91d0270eb436999d3772148cb71d8-ao-3
Published	09/25/2023	Bactrim, Augmentin, and Zosyn are all {{c1::combination}} drugs
Published	10/05/2023	Gram-{{c1::positive}}- {{c3::staphyl}}ococcus- {{c3::strept}}ococcus- {{c3::pneum}}ococcus- {{c3::enter}}ococcus- l{{c9::isteria}}- c{{c9::lostridium}…
Published	09/27/2023	cephalosporins- inhibit {{c1::cell wall}} synthesis (like pencillins)first generation: {{c2::Cefazolin}}- very first ones isolated from fungi&nbs…
Published	10/01/2023	DNA synthesis inhibitors aka. {{c1::quinolones}} = fluoro{{c1::quinolones}}- {{c3::gyrase}}: bacterial equivalent of human topoisomerase, as…
Published	09/25/2023	43877099c3c840a383ff9b6c192bed24-ao-1
Published	09/25/2023	43877099c3c840a383ff9b6c192bed24-ao-2
Published	09/25/2023	43877099c3c840a383ff9b6c192bed24-ao-3
Published	09/25/2023	43877099c3c840a383ff9b6c192bed24-ao-4
Published	09/25/2023	af950eaa9dc4478ca9716e6b2a0f69d0-ao-1
Published	09/25/2023	af950eaa9dc4478ca9716e6b2a0f69d0-ao-2
Published	09/25/2023	af950eaa9dc4478ca9716e6b2a0f69d0-ao-3
Published	09/25/2023	af950eaa9dc4478ca9716e6b2a0f69d0-ao-4
Published	09/25/2023	Metronidazole (aka {{c5::Flagyl}})- forms {{c1::nitroso radicals}} that disrupt DNA of microbial cells → inhibits nucleic acid synthesis → inhibi…
Published	09/25/2023	Rifampin (aka. Rifa{{c1::mycin}})- only clinically useful inhibitor of {{c2::RNA}} synthesis → used in treating {{c3::TB}}*has bright {{c4::red::color…
Published	09/26/2023	Inhibitors of bacterial {{c7::protein}} synthesis - amino{{c3::glycosides}} (streptomycin), line{{c4::zolid}} – inhibits initiation - tetra…
Published	10/05/2023	Drugs that affect cell membranes- {{c1:: Isoniazid (INH)}} inhibits synthesis of {{c2::mycolic acid}} ({{c4::60::#}} carbon-long fatty acids…
Published	09/26/2023	terminology bacteri{{c5::ostatic}} (stops growth) versus bacteri{{c5::cidal}} (kills) {{c4::narrow}} spectrum (works against one specific bacteria, e…
Published	09/27/2023	bacteriostatic vs. bactericidal drugsBacter{{c4::icidal}}: Penicillins, Aminoglycosides, Cephalosporins, Ciprofloxacin*kill the bacteria"PACC"Bac…
Published	09/25/2023	d45d25a0ad154e93bf57e43e0b0f2933-ao-1
Published	09/27/2023	{{c1::Empiric}} treatment comes from experience and history.... symptoms, age, travel, season, area they live in, etc. → helps in starting t…
Published	09/25/2023	mechanisms of developing drug resistance- {{c1::degrade}} the drugex: penicillinase (beta-lactamase) - change (mutate) drug {{c3::targets}}ex: alter…
Published	09/25/2023	{{c1::antibiotic}} resistance is one of the biggest threats to global health, food security, and development today→ can affect anyone, of any age, in …
Published	09/25/2023	Antibiotics for viral infections*although not exactly effective, reasons for prescription of antibiotics to patients with viral infections...- {{c1::p…
Published	11/02/2023	side effects of antibiotics- antibiotics kills intestinal bacterial flora → microbiome gets disturbed → {{c1::diarrhea}}*taking {{c3::probiotics}} aft…
Published	09/25/2023	{{c2::cell wall}} synthesis inhibitors = Penicillins, Cephalosporins, Vancomycin {{c3::protein}} synthesis inhibitor = Tetracyclines, Streptomyci…
Published	09/26/2023	Bactrim (Sulfamethoxazole + Trimethoprim) – anti-{{c1::metabolite}} Cephalosporins – inhibits {{c2::cell wall}} synthesis Ciprofloxacin – inhibits {{c…
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