Notes in Allergy & Hypersensitivity🦠 LECTURE 9

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Published	01/07/2025	What is an Allergy?
Published	01/07/2025	What is the following definition reffering to?Damaging immune response by the body to a substance (e.g. food, pollen, fur, dust) t…
Published	01/07/2025	What does allergy unnecessarily trigger?- increase in what 2 things?
Published	01/07/2025	What are the two types of allergic response?
Published	01/07/2025	What is a local allergic response?
Published	01/07/2025	What is a systemwide allergic response?
Published	01/07/2025	What are examples of local allergic responses?(3)
Published	01/07/2025	What is an example of a systemwide allergy?
Published	01/07/2025	What is hypersensitivity?
Published	01/07/2025	What does hypersensitivity result from?
Published	01/07/2025	The following defintion is reffering to what?An immune disorder caused by an inappropriate response to antigens that are not necessarily pat…
Published	01/07/2025	Hypersensitivites are divided into 3 categories, how do these categories differ?
Published	01/07/2025	Allergy is an example of a {{c1::hypersensitivity}} disorder, and the substances (antigens) that cause allergies are known as {{c1::allergens}}.
Published	01/07/2025	What are allergens?
Published	01/07/2025	Antigens that cause allergyWhat is this definition referring to?
Published	01/07/2025	When are antigens more likely to cause bad allergy?
Published	01/07/2025	What are the 4 categories of hypersensitivity?
Published	01/07/2025	Describe type I: antibody mediated hypersensitvity(4)- caused by which antibodies?- this antibody binds to variable regions on? that then binds to whi…
Published	01/07/2025	What type of hypersensitivity is an allergy?
Published	01/07/2025	When do healthy individuals generally produce IgE antibodies?
Published	01/07/2025	What is one requirement the allergen must have to be able to cause cross-linking?Give an example of a structure that is perfect for this.
Published	01/07/2025	What is atopy?what type of disposition leading to production of elevated levels of which antibody?
Published	01/07/2025	What is the following definition reffering to?Genetic disposition to develop an allergic reaction and produce elevated levels of IgE in response to an…
Published	01/07/2025	What happens on first exposure of allergen? And then re-exposure to the same allergen.After first exposure to antigen allergen: - production of w…
Published	01/07/2025	As degranulation occurs and vasoactive amines are released, what does the inflammatory response entail that eventually results in disease?(6)
Published	01/07/2025	Describe the asthmatic response (4)
Published	01/07/2025	During the asthmatic response, what is contraction of bronchial and smooth muscle mediated by?
Published	01/07/2025	During the asthmatic response, histamine binds to a H1 receptor where?
Published	01/07/2025	In the asthmatic response: when an individual feels a congested feeling in the nose/throat, why is this ?
Published	01/07/2025	Upon degranulation, what is the name of the enzyme that intiates enzymatic breakdown of p________ in the plasma membrane?
Published	01/07/2025	Give 2 inflammatory mediators that are 1000X more active than histamine.
Published	01/07/2025	Why do some responses in asthma take longer to develop? (5)
Published	01/07/2025	Describe the type II: cytotoxic hypersensitivity response:- which antibodies are involved?-  which 3 adaptive immune responses trigger destructio…
Published	01/07/2025	How can transfuse reactions result in hypersensitivity disorder?
Published	01/07/2025	What is haemolytic disease of the newborn? (3)
Published	01/07/2025	What happens in malaria?
Published	01/07/2025	What is drug-induced haemolytic anaemia?
Published	01/07/2025	Describe type III: Immune-complex mediated hypersensitivity disorder(4)- degranulation of? triggered by activation of which system? activation of whic…
Published	01/07/2025	In healthy individuals, immune complexes of antibody and antigens are usually cleared by what?
Published	01/07/2025	Where can immune complexes be deposited?
Published	01/07/2025	Desposition of immune complexes in kidney can lead to what?
Published	01/07/2025	Describe type IV: cell-mediated hypersensitivity- mediated by which cells?- requires these cells to be what to antigen? what phase does this happen in…
Published	01/07/2025	After how long do type IV hypersensitivity symptoms appear?
Published	01/07/2025	What are the effects of macrophage activation?(4)
Published	01/07/2025	What are examples of serious conditions that can include a cough?
Published	01/07/2025	What could trigger coughing?(3)
Published	01/07/2025	What are the red flags associated with coughing? (10)
Published	01/07/2025	In humans, what are leukotrienes thought to contribute to?
Published	01/07/2025	What is the following definition reffering to?Red blood cells that become coated in metabolites trigger immune responses that cause a breakdown of tho…
Published	01/07/2025	In type III hypersensitivity, what triggers degranulation?
Published	01/07/2025	What is type IV (cell mediated) hypersensitivity also known as?DTH is purely _____ mediated
Published	01/07/2025	Describe the sensitisation phase in type IV hypersensitivity:what is triggered during initial contact with antigen presented by an APCWhat is secreted…
Published	01/07/2025	what does the effector phase involve in type IV hypersensitivity:what does the sensitised T cell produce upon re-exposure to the antigen?what does thi…
Published	01/07/2025	what are the inducers of type IV hypersensitivity?
Published	01/07/2025	what are the diseases resulting from type III hypersensitivity?
Published	01/07/2025	87214aaf8f61425fa15fc45ae7ac1699-ao-1
Published	01/07/2025	d0013913c30947c2b4ddbb122d3ed502-ao-1
Published	01/07/2025	What are the allergens associated with type I hypersensitivity?
Published	01/07/2025	51df99f3e31040df83054c58a1bd8df7-ao-1
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