Notes in Week 7

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Published 11/14/2023 The glomerular basement membrane contains {{c1::heparan sulfate}}, which has a {{c2::negative}} charge to keep out molecules like {{c3::albumin}} in t…
Published 11/14/2023 Minimal change disease: Pathophys: cytokine damages {{c1::podocyte foot processes}}Imaging: Foot process {{c2::effacement}} on {{c3::electron microsco…
Published 11/14/2023 Diabetic nephropathy:Pathophys: glycosylation of GBM in {{c2::efferent}} arterioles causing {{c3::constriction}}, eventually leading to {{c4::fibrosis…
Published 11/14/2023 Focal segmental glomerulosclerosis:Pathophys: damage to {{c1::podocytes}}Imaging: {{c2::localized}} sclerosis on light microscopy
Published 11/14/2023 Membranous nephropathy:Pathophys: Antibodies against {{c3::phospholipase A2}} receptor deposit in subepithelial spaceImaging: {{c1::spike-and-dome}} o…
Published 11/14/2023 Membranoproliferative glomerulonephritis:Pathophys: immune complex deposits in {{c1::subendothelial}} spaceImaging: {{c2::tram-track}} appearance on {…
Published 11/14/2023 Post-infectious glomerulonephritis:Pathophys: After infection, circulating immune complexes lodge in {{c2::GBM}}Imaging: "{{c1::subepithelial humps}}"…
Published 11/14/2023 IgA nephropathy:Pathophys: IgA antibodies react and lodge in {{c1::mesangium}}Imaging: {{c1::mesangial}} expansion, high serum IgA
Published 11/14/2023 Anti-GBM nephritis:Pathophys: antibodies against {{c4::type IV collagen}}Imaging: {{c2::crescent}} lesion (indicates {{c3::rapidly progressive glomeru…
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