Notes in Urea Cycle

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Status	Last Update	Fields
Published	08/28/2024	Carbamoyl phosphate synthetase I is regulated via positive feedback by {{c1::N-acetylglutamate}}
Published	08/28/2024	Where can the body get amino acids?{{c1::Diet}}{{c1::Break down of cells / proteins}}
Published	08/28/2024	What is the purpose of the Urea Cycle?Converts {{c1::NH4}} + to {{c1::urea}}
Published	08/28/2024	When Amino Acids are broken down, what happen to the constituents?NH4+: {{c1::Urea Cycle}}Carbon Skeleton: {{c1::TCA Cycle}}
Published	08/28/2024	What are the three steps of Nitrogen Excretion?1) AA does {{c1::transamination}} via an {{c1::Aminotransferase + PLP}}2) {{c1::Oxidative Dea…
Published	08/28/2024	^ [NH4+] / hyperammonemia --> {{c1::severe brain injury}}
Published	08/28/2024	What is the committed step of the Urea Cycle?Step #1: Making carbamoyl phosphate via {{c1::Carbamoyl Phosphate Sythetase I}}
Published	08/28/2024	Does the Urea Cycle happen in the mito. matrix or the cytoplasm?{{c1::Both. First 2 steps in mito, the rest = in cytoplasm}}
Published	08/28/2024	Which 2 intermediates of the Urea Cycle can cross the inner mito. membrane?{{c1::Citrulline}}{{c1::Ornithine}}
Published	08/28/2024	Draw out the Urea Cycle{{c1:::)}}Arginase only found in {{c1::liver}}
Published	08/28/2024	How can you ^ activity of Carbamoyl Phosphate Synthetase I?{{c1::N-acetylglutamate}}
Published	08/28/2024	Ultimately, why do we need the Urea Cycle?Cant {{c1::store AAs :(}}
Published	08/28/2024	{{c1::Glucogenic AAs}} produce carbon skeletons that can turn into glucose{{c1::Ketogenic AAs}} produce carbon skeletons that can turn into ketone bod…
Published	08/28/2024	What disease happens when phenylalanine hydroxylase is missing?{{c1::PKU (phenylketonuria)}}Treat by diet: dont eat {{c1::phenylalanine}}, eat ex…
Published	08/28/2024	Which organ is where the urea cycle takes place?{{c1::Liver}}
Published	08/28/2024	What enzyme forms NH4+ during oxidative deamination in nitrogen metabolism?{{c1::glutamate dehydrogenase}}
Published	08/28/2024	In the urea cycle, what regulates N-acetylglutamate synthase?{{c1::arginine}}
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