Notes in Week 14 - Pharmacology of Muscle Relaxants & Anti-Spastic Drugs

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Published	11/01/2024	What route of administration are neuromuscular blockers administered?{{c1::IV}}
Published	11/01/2024	Do neuromuscular blockers cross the blood-brain barrier?{{c1::No}}
Published	11/01/2024	Nondepolarizing neuromuscular blockers are most effective at {{c1::low}} doses
Published	11/01/2024	Sugammadex acts by binding to {{c1::steroid::steroid or isoquinoline}}-type {{c1::non-depolarizing::depolarizing or non-depolarizing}} neuro…
Published	11/01/2024	Which non-depolarizing neuromuscular blockers are associated with histamine release?- {{c1::Atracurium}}- {{c1::Mivacurium}}- {{c1…
Published	11/01/2024	Non-depolarizing neuromuscular blockers are associated with {{c1::less}} autonomic side effects
Published	11/01/2024	What class of antibiotics enhances the effects of neuromuscular blockers?{{c1::Aminoglycosides}}
Published	11/01/2024	{{c1::Isoflurane}} is an inhaled anesthetic that most significantly enhances the effects of neuromuscular blockers
Published	11/01/2024	Which class of cardiovascular drugs enhances the effects of neuromuscular blockers?{{c1::Antiarrhythmics}}
Published	11/01/2024	{{c2::Depolarizing}} neuromuscular blockers are often administered {{c1::after}} anesthesia induction over the chest and abdomen
Published	11/01/2024	{{c2::Non-depolarizing}} neuromuscular blockers are often administered {{c1::during}} anesthesia induction over skeletal muscle
Published	11/01/2024	{{c1::Rocuronium}} is a non-depolarizing neuromuscular blocker with the fastest onset
Published	11/01/2024	{{c1::Atracurium}} is a non-depolarizing neuromuscular blocker that can cause seizures
Published	11/01/2024	{{c1::Vecuronium}} and {{c1::rocuronium}} are non-depolarizing neuromuscular blockers that are metabolized by the {{c2::liver}}
Published	11/01/2024	{{c1::Pancuronium}} is a non-depolarizing neuromuscular blocker that is metabolized by the {{c2::kidney}}
Published	11/01/2024	{{c1::Pancuronium}} is a non-depolarizing neuromuscular blocker with the longest duration of action
Published	11/01/2024	{{c1::Mivacurium}} is a non-depolarizing neuromuscular blocker with the shortest duration of action
Published	11/01/2024	The {{c1::dibucaine number}} is a measurement of the percentage of pseudocholinesterase activity that is inhibited by dibucaine
Published	11/01/2024	What enzyme breaks down succinylcholine?{{c1::Plasma cholinesterase / butyryl-cholinesterase / pseudocholinesterase}}
Published	11/01/2024	{{c1::Mivacurium}} is the only non-depolarizing neuromuscular blocker that is metabolized by pseudocholinesterase
Published	11/01/2024	{{c1::Baclofen}} is a spasmolytic drug that decreases type {{c2::Ia}} sensory nerve fiber activity
Published	11/01/2024	{{c1::Baclofen}} is a spasmolytic that does not reduce muscle strength
Published	11/01/2024	{{c1::Cyclobenzaprine}} is a spasmolytic drug that is primarily used for acute, local muscle spasms
Published	11/01/2024	Non-depolarizing neuromuscular blockers are {{c1::competitve}} antagonists of acetylcholine
Published	11/01/2024	Which one of the above produces muscle paralysis by depolarizing muscle cell membranes?A. baclofenB. cyclobenzaprineC. dantroleneD. rocuroniumE. succi…
Published	11/01/2024	The effects of this drug can be shortened by addition of acetylcholinesterase inhibitors like neostigmineA. baclofenB. cyclobenzaprineC. dantroleneD. …
Published	11/01/2024	A 47-year-old man has a routine surgical procedure. He is anesthetized with an inhaled anesthetic. Shortly after the use of the anesthetic agent he ex…
Published	11/01/2024	A 34-year-old woman with multiple sclerosis is being treated for muscle spasm and pain with a drug that activates GABA-B, g-protein coupled, receptors…
Published	11/01/2024	The use of this drug is associated with histamine release, bradycardia, and stimulation of autonomic ganglionic nicotinic receptorsA. baclofenB. cyclo…
Published	11/01/2024	A 47-year-old has an acute spasm that results from a muscle injury. He is treated with an oral drug that has pronounced antimuscarinic action and prod…
Published	11/01/2024	A 15-year-old patient with cerebral palsy is treated with a drug that activates GABA-b-metabotropic receptors in the spinal column to reduce neuronal-…
Published	11/01/2024	Which one of the above produces muscle paralysis by depolarizing muscle cell membranes?A. Botulinum Toxin B. Dantrolene C. Diazepam D. Rocuronium E. S…
Published	11/01/2024	Increases in acetylcholine at the neuromuscular junction reduce the effects of this drug by displacing it from the nicotinic-Ach receptor.A. Botulinum…
Published	11/01/2024	Injection of this drug cleaves synaptic vesicle docking-and-fusion-proteins preventing release of acetylcholine. A. Botulinum Toxin B. Dantrolene C. D…
Published	11/01/2024	Based on its mechanism of action what would be the expected toxicities of a depolarizing muscle relaxant? (if A-C are all correct mark D, if A-C are n…
Published	11/01/2024	A 25-year-old man requires skeletal muscle relaxation prior to a short surgical procedure. The surgeon commands that the entire procedure must last ap…
Published	11/01/2024	Administration of this drug is associated with hyperkalemia, increased intraocular pressure, post-operative muscle pain and stimulation of both nicoti…
Published	11/01/2024	The effects of this drug can be greatly shortened by administration of neostigmineA. BaclofenB. DantroleneC. SuccinylcholineD. TizanidineE. Vecuronium…
Published	11/01/2024	A 30-year-old man previously diagnosed with multiple sclerosis requires a therapy to provide symptomatic relief from painful spasm in his legs. After …
Published	11/01/2024	A 30-year-old man previously diagnosed with multiple sclerosis requires a therapy to provide symptomatic relief from painful spasm in his legs. After …
Published	11/01/2024	Which statement is correct?A. Baclofen enzymatically cleaves synaptic vesicle docking and fusion proteinsB. Botulinum Toxin use is reserved for patien…
Published	11/01/2024	A 44-year-old male patient is undergoing calf-implant augmentation surgery. He has been embarrassed for years about his spindly lower limbs. The patie…
Published	11/01/2024	A difference between vecuronium and succinylcholine is thatA. Succinylcholine produces less histamine releaseB. Vecuronium has a faster onset and shor…
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