Notes in Case 01: Myocardial Infarction

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Status	Last Update	Fields
Published	09/21/2023	ST elevation = {{c1::STEMI::STEMI/NSTEMI}} = infarction of {{c1::the whole wall (transmural infarct)}}
Published	09/21/2023	ST depression = {{c1::NSTEMI::STEMI/NSTEMI}} = infarction of {{c1::part of the wall (subendocardial infarct)}}
Published	09/25/2023	Skeletal muscle is innervated by the {{c1::somatic nervous system}}Smooth muscle is innervated by the {{c1::autonomic nervous system}}Cardiac muscle i…
Published	09/21/2023	Troponin C {{c1::binds calcium, causing I subunit release from tropomyosin::does what?}}
Published	09/21/2023	Troponin I {{c1::inhibits actomyosin interaction (commonly used to detect MIs)::does what?}}
Published	09/21/2023	Troponin T {{c1::binds to tropomyosin (to stabilize) (also used to detect MIs)::does what?}}
Published	09/21/2023	{{c1::Oxidized LDL}} buildup → macrophages consume {{c1::Oxidized LDL}} and become {{c2::foam cells}} → {{c2::foam cells}} rupture and die → {{c3…
Published	09/21/2023	Aspirin mechanism of action:Blocks {{c1::COX-1::enxyme}} synthesis of {{c1::prostaglandins and TXA2}} → prevents activation of {{c2::thromboxane …
Published	09/28/2023	Prasugrel mechanism of action:Inhibits {{c1::P2Y12 ADP receptor}} → prevents platelet {{c2::beta granule secretion}} → prevents conform…
Published	09/21/2023	Metoprolol mechanism of action:Inhibits {{c1::β1 receptors}}, preventing {{c1::epinephrine}} from binding→ decreases activation of the {{c2::Qs}}…
Published	09/21/2023	Lisinopril mechanism of action:Inhibits {{c1::ACE}} from converting {{c1::angiotensin I}} to {{c1::angiotensin II}} → {{c2::dialates blood vessel…
Published	09/21/2023	Statin mechanism of action:Blocks {{c1::HMG-CoA reductase}} from converting {{c1::HMG-CoA to mevalonate}} → {{c2::decreased cholesterol synthesis}} an…
Status	Last Update	Fields