Notes in Upper GI

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Published	02/18/2024	List the three broad categories of genetic mutations that are involved in the molecular pathogenesis of pancreatic cancer. (2 marks)
Published	02/18/2024	List risk factors for development of exocrine pancreatic cancer
Published	02/18/2024	List inherited cancer syndromes and associated genes in pancreatic cancer
Published	02/18/2024	List the poor prognostic factors for survival in a patient who has undergone a pancreaticoduodenectomy for pancreatic ductal adenocarcinoma
Published	02/18/2024	Pancreatic ductal adenocarcinoma - macroscopic and microscopic features
Published	02/18/2024	Pancreatic adenocarcinoma - biological behaviour
Published	02/18/2024	List differential diagnosis for a solitary liver lesion
Published	02/18/2024	Describe key clinical and investigative measures to establish a diagnosis of HCC
Published	02/18/2024	HCC - epidemiology
Published	02/18/2024	HCC - risk factors
Published	02/18/2024	HCC - macroscopic and microscopic features
Published	02/18/2024	Describe the mechanism of viral carcinogenesis in the development of HCC
Published	02/18/2024	Differentials for malignant stomach lesion
Published	02/18/2024	Gastric carcinoma - describe risk factors and aetiology
Published	02/18/2024	Gastric adenocarcinoma - Gross macroscopic classification
Published	02/18/2024	Gastric adenocarcinoma - WHO classification of microscopic subtypes (5 major ones)
Published	02/18/2024	Compare and contrast the epidemiological, clinical and histopathological features of Intestinal Vs Diffuse Gastric Adenocarcinomas.
Published	02/18/2024	Barrett’s oesophagus: Macroscopic and microscopic appearance
Published	02/18/2024	Barrett's oesophagus: Pathogenesis and clinical significance
Published	02/18/2024	Regarding adenocarcinoma and squamous cell carcinoma of the oesophagus: Compare and contrast the epidemiology and risk factors
Published	02/18/2024	Regarding adenocarcinoma and squamous cell carcinoma of the oesophagus: List the microscopic and immunohistochemical features.
Published	02/18/2024	After neoadjuvant chemoradiotherapy: i. Describe the microscopic changes in the tumour and adjacent tissues.
Published	02/18/2024	List the pathological prognostic factors in an oesophagectomy specimen
Published	02/18/2024	Assessment of ACUP
Published	02/18/2024	Value of tumour markers in diagnosis and management of ACUP
Published	02/18/2024	Favourable prognostic factors in ACUP
Published	02/18/2024	Name suitable empirical chemotherapy combinations for ACUP
Published	02/18/2024	Taxane toxicities
Published	02/18/2024	Outline possible causes of cahexia in a patient with advanced gastric cancer
Published	02/18/2024	Describe pharmacological and non-pharmacological measures in the management of cahexia in advanced malignancy
Published	02/18/2024	What are the options for local palliation of gastric cancer bleeding? Include in your answer the advantages and disadvantages of each option. (3)
Published	02/18/2024	In general, what palliative options are there to manage malignant haemorrhage?
Published	02/18/2024	Discuss the treatment options for resectable adenocarcinoma of the stomach with no evidence of distant metastatic disease
Published	02/18/2024	Gastric adenocarcinoma - describe your radiation technique for post-operative chemotherapy
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