Notes in 01_Haemophilia A and B

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Published 02/10/2024 {{c1::Haemophilia A}} is a genetic clotting disorder caused by deficiency of factor {{c2::VIII}}
Published 02/10/2024 {{c1::Haemophilia B}} is an X-linked recessive clotting disorder caused by deficiency of factor {{c2::IX}}
Published 02/10/2024 Presentation of {{c2::Severe Haemophilia A and B}} {{c1::Haemarthrosis and Haematomas (bleeding into muscles and joints >30 times a year)}} {{c1::G…
Published 02/10/2024 Investigations of {{c2::Haemophilia A}} {{c1::Low Hb (if frequent or recent bleeding)}} {{c1::Mixing Study: Prolonged aPTT }} {{c1::Factor VIII a…
Published 02/10/2024 Investigations of {{c2::Haemophilia B}} {{c1::Low Hb (if frequent or recent bleeding)}} {{c1::Mixing Study: Prolonged aPTT }} {{c1::Factor IX ass…
Published 02/10/2024 Prevention of Bleeding in Haemophilia A and B {{c1::Prophylactic infusions of factor VIII for Haemophilia A}} {{c1::Prophylactic infusions of factor I…
Published 02/10/2024 Treatment of Acute Bleeding Episodes of Haemophilia A {{c1::Administer dose of recombinant factor VIII}} {{c1::If unsuccessful or unavailable, use Fre…
Published 02/10/2024 Treatment of Acute Bleeding Episodes of Haemophilia B {{c1::Administer dose of recombinant factor IX}}{{c1::If unsuccessful or unavailable, use Fresh …
Published 02/10/2024 Treatment of Haemarthrosis Secondary to Haemophilia {{c1::Splints}} {{c1::Physiotherapy}} {{c1::Analgesia}} {{c1::Synovectomy}} {{c1::Joint repla…
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