Notes in Week 1 Breast cancer PBL

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Published 08/30/2023 BRCA1 and 2 mutations are {{c1::autosomal dominant}} [inheritance pattern]
Published 08/30/2023 breast cancer diagnosis usually begins with feeling a {{c1::breast lump}}
Published 08/30/2023 Breast cancer is often asymptomatic until {{c1::metastisis}}
Published 08/30/2023 breast cancer treatment is based on the cancer's {{c1::type and stage}}
Published 08/30/2023 breast carcinoma is defined as the uncontrolled growth of {{c1::epithelial}} cells within the breast
Published 08/30/2023 breast glandular tissue produces milk and are comprised of {{c1::lobules}}
Published 08/31/2023 DCIS tumor cells secrete {{c1::mobility factor}} to help invade squamous epithelium
Published 08/30/2023 hormone receptors present in glandular tissue and their function
Published 08/30/2023 describe lobule structure
Published 08/30/2023 if {{c1::ductal caricinoma in situ}} is not treated it can cross the basement membrane to become {{c2::an invasive ductal carcinoma}}
Published 08/30/2023 in situ carcinomas from mutated epithelial cells initially localize to the {{c1::basement membrane}} of alveoli
Published 08/31/2023 lymphatics lie directly below the skin of the breast and drain into the {{c1::axillary lymph nodes}}
Published 08/30/2023 metastis to the axillary lymph nodes or other breast is via {{c1::lymph}}
Published 08/30/2023 metastis to the brain, bone, or spine is by {{c1::blood}}
Published 08/30/2023 mutations in {{c1::BRCA1, BRCA2, TP53, and ERBB2}} are common causes of breast cancer
Published 08/30/2023 risk factors associated with increased/decreased risk of breast cancer
Published 08/30/2023 the breasts are kept in place by {{c1::cooper's ligaments}}
Published 08/31/2023 the {{c1::TNM system}} is used to assign the {{c2::stage group}} of the breast cancer
Published 08/31/2023 tumor formation typically occurs where? In {{c1::epithelial cells lining a duct or a lobule}}
Published 08/30/2023 what are some complications of breast cancer?
Published 08/30/2023 what are some symptoms of breast cancer?
Published 08/30/2023 {{c1::alveolar cells}} secrete milk into alveolus lumen
Published 08/30/2023 {{c1::lobular carcinoma in situ (LCIS)}} happens when tumors grow in clusers and cause the alveoli to enlargent
Published 08/30/2023 {{c1::Paget disease of the nipple}} is caused by DCIS migration to nipple skin
Published 08/30/2023 {{c1::peau d'orange}} occurs when {{c2::inflammatory edema}} from restricted lymphatics is restricted by suspesory ligament attachment
Published 08/30/2023 {{c1::stroma}} make up most of breast tissue
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