Notes in Osmosis

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Published	10/11/2024	What is the MOA of Argatroban and Bivalirudin (hirudin anticoagulants)?
Published	10/11/2024	What is the most common adverse effect of Apixaban and Rivaroxaban (Factor Xa inhibitors)?
Published	10/11/2024	Deep Vein Thrombosis Low molecular weight heparin, such as enoxaparin, is used to treat {{c1::acute::acute/ chronic}} deep vein thrombosis.
Published	10/11/2024	In a patient with patent foramen ovale, deep vein thrombosis is a risk factor for a {{c1::paradoxical embolism}}.
Published	10/11/2024	{{c1::Heparin}} is an anticoagulant that is preferentially used to prevent and acutely manage deep venous thrombosis.
Published	10/11/2024	The most common symptom of deep venous thrombosis is {{c1::leg swelling}}.
Published	10/11/2024	{{c1::Homans sign}} is a clinical maneuver to detect deep vein thrombosis and is characterized by calf pain upon dorsiflexion of the foot.
Published	10/11/2024	{{c1::Well's score}} is the scoring system used to stratify the risk of having deep venous thrombosis.
Published	10/11/2024	{{c1::Compression ultrasound with doppler}} is the imaging test of choice to diagnose deep venous thrombosis.
Published	10/11/2024	{{c1::Venography}} is the most specific test for diagnosing deep venous thrombosis.
Published	10/11/2024	Most pulmonary emboli arise from {{c1::proximal::proximal/distal}} deep veins of lower limbs.
Published	10/11/2024	{{c1::Warfarin}} is an oral vitamin K antagonist that is used for prophylaxis against deep venous thrombosis and has a teratogenic effect.
Published	10/11/2024	Deep venous thrombosis is a clotting disorder that involves the development of a {{c1::blood clot within a deep vein of the leg}}.
Published	10/11/2024	The {{c1::D-dimer}} laboratory serum test is a diagnostic test used to clinically rule out deep vein thrombosis due to its high sensitivity.
Published	10/11/2024	Deep venous thrombosis is the most common cause of {{c1::pulmonary embolism}}.
Published	10/11/2024	Virchow's triad, used to describe the pathogenesis of deep vein thrombosis, includes {{c1::venous stasis}}, {{c2::endothelial cell damage}}, and a {{c…
Published	10/11/2024	Anticoagulants : Direct factor inhibitors Either {{c1::direct thrombin inhibitors::medication class}} or fondaparinux are used instead of heparin in p…
Published	10/11/2024	{{c1::Rivaroxaban}} is an anticoagulant that is used to treat and prevent pulmonary embolism by directly binding to and inhibiting the activity of Fac…
Published	10/11/2024	{{c1::Dabigatran etexilate}} is an anticoagulant that is a prodrug. Once activated it directly inhibits both free and clot-bound thrombin.
Published	10/11/2024	{{c1::Lepirudin}}, {{c2::bivalirudin}}, and {{c3::desirudin}} are hirudin analogs that act as direct thrombin inhibitors; these compounds were origina…
Published	10/11/2024	{{c1::Apixaban}} and {{c2::Rivaroxaban}} are anticoagulants that function by binding to and directly inhibiting the activity of Factor Xa.
Published	10/11/2024	Anticoagulants : Heparin The most common adverse effect of heparin is {{c1::bleeding}}.
Published	10/11/2024	The half-life of heparin is {{c1::short::short/long}}.
Published	10/11/2024	{{c1::Low molecular weight heparin}} is the form of heparin that does not require laboratory monitoring.
Published	10/11/2024	{{c1::Thrombin (Factor IIa) and factor Xa}} are two coagulation factors primarily targeted by heparin.
Published	10/11/2024	{{c1::Low molecular weight heparin}} is the type of heparin which has better bioavailability and two to four times longer half-life.
Published	10/11/2024	Heparin is the drug of choice for the prevention and acute management of {{c1::deep venous thrombosis}}.
Published	10/11/2024	{{c1::Partial thromboplastin time}} is the bleeding parameter that we use to monitor the effect of heparin.
Published	10/11/2024	{{c1::Thrombocytopenia}} is the hematological toxicity of heparin.
Published	10/11/2024	The route of administration of heparin is {{c1::parenteral; intravenous or subcutaneous}}.
Published	10/11/2024	Heparin is an anticoagulant medication that enhances the activity of {{c1::antithrombin}}.
Published	10/11/2024	Heparin is an anticoagulant that can be found in the dense granules of {{c1::basophils}}.
Published	10/11/2024	{{c1::Heparin}} is the medication of choice to achieve immediate anticoagulation.
Published	10/11/2024	{{c1::Enoxaparin}} and {{c2::Dalteparin}} are two low-molecular-weight heparins that function similarly to normal heparin, however they act more on fa…
Published	10/11/2024	{{c1::Protamine sulfate}} is the treatment for Heparin toxicity.
Published	10/11/2024	{{c1::Factors II, IX, X, XI, XII}} are the coagulation factors that high molecular weight heparin inhibits.
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